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Specialty: Radiology
Therapy: Radiation Therapy

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Total 1016 results found since Jan 2013.

Dosimetry in Lu-177-DOTATATE peptide receptor radionuclide therapy: a systematic review
ConclusionAccording to the present dosimetric review,177Lu-DOTATATE PRRT appears to be a safe and reliable treatment option for advanced GEP-NETs. From the dosimetric point of view, kidneys are theoretically the major organs at risk in177Lu-DOTATATE treatment. The optimization of the number of treatment cycles beyond the prescribed limit of four and the maximum administered activity in each cycle must be determined by individual patient dosimetry in order to reduce the risk of organ toxicities whilst maximizing therapeutic efficacy.
Source: Clinical and Translational Imaging - September 20, 2023 Category: Radiology Source Type: research

Trauma-Informed Care in Medical Imaging and Radiation Therapy to Reduce Retraumatization
CONCLUSION: Because many aspects of care, including routine care in medical imaging and radiation therapy, can be an unintentional reminder of a traumatic experience, health care professionals should be trauma-informed when they are interacting with and caring for patients.PMID:37709517
Source: Radiologic Technology - September 14, 2023 Category: Radiology Authors: Kevin R Clark Jennifer S Sonsiadek Source Type: research

Monte Carlo-based optimization of glioma capsule design for enhanced brachytherapy
Appl Radiat Isot. 2023 Sep 5;201:111014. doi: 10.1016/j.apradiso.2023.111014. Online ahead of print.ABSTRACTThe use of radiotherapy in tumor treatment has become increasingly prominent and has emerged as one of the main tools for treating malignant tumors. Current radiation therapy for glioma employs 125I seeds for brachytherapy, which cannot be combined with radiotherapy and chemotherapy. To address this limitation, this paper proposes a dual-microcavity capsule structure that integrates radiotherapy and chemotherapy. The Monte Carlo simulation method is used to simulate the structure of the dual-microcavity capsule with ...
Source: Applied Radiation and Isotopes - September 9, 2023 Category: Radiology Authors: Dongjie Li Yu Liang Gang Yao Zhongbao Guan Hongtao Zhao Nan Zhang Jicheng Jiang Weida Gao Source Type: research

Development and clinical implementation of a digital system for risk assessments for radiation therapy
Z Med Phys. 2023 Sep 2:S0939-3889(23)00092-2. doi: 10.1016/j.zemedi.2023.08.003. Online ahead of print.ABSTRACTBefore introducing new treatment techniques, an investigation of hazards due to unintentional radiation exposures is a reasonable activity for proactively increasing patient safety. As dedicated software is scarce, we developed a tool for risk assessment to design a quality management program based on best practice methods, i.e., process mapping, failure modes and effects analysis and fault tree analysis. Implemented as a web database application, a single dataset was used to describe the treatment process and its...
Source: Zeitschrift fur Medizinische Physik - September 4, 2023 Category: Radiology Authors: Dominik Kornek David Menichelli J örg Leske Michael Hofmann David Antkiewicz Tobias Brandt Oliver J Ott Michael Lotter Marga Lang-Welzenbach Rainer Fietkau Christoph Bert Source Type: research

SpaceOAR hydrogel distribution and early complications in patients undergoing radiation therapy for prostate cancer
CONCLUSIONS: Transperineal hydrogel placement separates the prostate from the rectum with a symmetrical distribution in the majority of cases prior to radiation therapy with a low rate of rectal wall injection and immediate complications.ADVANCES IN KNOWLEDGE: SpaceOAR hydrogel can be safely injected into radiation naive patients with low or intermediate-risk organ-confined prostate cancer. The spacer separates the prostate from the rectum with a symmetrical distribution in the majority of cases prior to radiation therapy.PMID:37660394 | DOI:10.1259/bjr.20220947
Source: The British Journal of Radiology - September 3, 2023 Category: Radiology Authors: Andrew H Yates Jack W Power Philip J Dempsey Adam Agnew Brian D Murphy Richard Moore Mazen El Bassiouni Michelle M J McNicholas Source Type: research

Accounting for fractionation and heterogeneous dose distributions in the modelling of osteoradionecrosis in oropharyngeal carcinoma treatment
CONCLUSION: Risk models for ORN based on conventional DVH parameters cannot be directly applied to HF-SBRT fractionation schemes and dose distributions. However, after correcting for fractionation and non-uniform dose distributions using EUD, a single model can distinguish between ORN and non-ORN after conventionally fractionated radiotherapy and hypofractionated boost treatments.PMID:37659662 | DOI:10.1016/j.radonc.2023.109889
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Gerda M Verduijn Nienke D Sijtsema Yvette van Norden Wilma D Heemsbergen Hetty Mast Aniel Sewnaik Denzel Chin Sarah Baker Marta E Capala Aad van der Lugt Esther van Meerten Mischa S Hoogeman Steven F Petit Source Type: research

Primary tumor site for localized Merkel cell carcinoma drives different management strategies without impacting oncologic outcomes
CONCLUSIONS: Among patients with primary MCC who had RT as a component of their initial treatment strategy, anatomically-driven heterogeneous treatment approaches were associated with equally excellent locoregional disease control.PMID:37659660 | DOI:10.1016/j.radonc.2023.109892
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Samuel Cass Brandon Cope Andrew J Bishop Yi-Ju Chiang B Ashleigh Guadagnolo Ahsan Farooqi William Morrison Russell G Witt Riyad N H Seervai Adam S Garden Clifton D Fuller Ryan P Goepfert Merrick Ross Jeffrey E Gershenwald Michael Wong Phyu P Aung Emily Z Source Type: research

Need for standardization in the use of structures in the intensity-modulated radiation therapy planning of head and neck cancers, a GORTEC study
Conclusion Use of nsRS is frequent but heterogeneous and should be standardized further in line with ICRU initiatives in IMRT planning. Use of nsRS should be documented with respect to the need for nsRS from dose computation algorithms of treatment planning systems and IMRT machines in terms of modulation capacity and plan robustness.PMID:37659657 | DOI:10.1016/j.radonc.2023.109895
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Özgür Özer Hanaan Shafi David O'Reilly Cedric Loiseau Catherine Dejean Jean Bourhis Juliette Thariat Source Type: research

Accounting for fractionation and heterogeneous dose distributions in the modelling of osteoradionecrosis in oropharyngeal carcinoma treatment
CONCLUSION: Risk models for ORN based on conventional DVH parameters cannot be directly applied to HF-SBRT fractionation schemes and dose distributions. However, after correcting for fractionation and non-uniform dose distributions using EUD, a single model can distinguish between ORN and non-ORN after conventionally fractionated radiotherapy and hypofractionated boost treatments.PMID:37659662 | DOI:10.1016/j.radonc.2023.109889
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Gerda M Verduijn Nienke D Sijtsema Yvette van Norden Wilma D Heemsbergen Hetty Mast Aniel Sewnaik Denzel Chin Sarah Baker Marta E Capala Aad van der Lugt Esther van Meerten Mischa S Hoogeman Steven F Petit Source Type: research

Primary tumor site for localized Merkel cell carcinoma drives different management strategies without impacting oncologic outcomes
CONCLUSIONS: Among patients with primary MCC who had RT as a component of their initial treatment strategy, anatomically-driven heterogeneous treatment approaches were associated with equally excellent locoregional disease control.PMID:37659660 | DOI:10.1016/j.radonc.2023.109892
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - September 2, 2023 Category: Radiology Authors: Samuel Cass Brandon Cope Andrew J Bishop Yi-Ju Chiang B Ashleigh Guadagnolo Ahsan Farooqi William Morrison Russell G Witt Riyad N H Seervai Adam S Garden Clifton D Fuller Ryan P Goepfert Merrick Ross Jeffrey E Gershenwald Michael Wong Phyu P Aung Emily Z Source Type: research