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Vaccination: Whooping Cough (Pertussis) Vaccine
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Total 1097 results found since Jan 2013.
Shotgun proteomic analysis of Bordetella parapertussis provides insights into the physiological response to iron starvation and potential new virulence determinants absent in Bordetella pertussis.
This study reports the first extensive proteome analysis of this bacterium. In an attempt to gain some insight into the infective phenotype, we evaluated the response of B. parapertussis to iron starvation, a critical stress the bacteria face during infection. Among other relevant findings, we observed that the adaptation to this condition involves significant changes in the abundance of two important virulence factors of this pathogen, namely, adenylate cyclase and the O-antigen. We further used the proteomic data to search for B. parapertussis proteins that are absent or classified as pseudogenes in the genome of Bordete...
Source: Journal of Proteomics - July 16, 2019 Category: Biochemistry Authors: Oviedo JM, Surmann K, Gorgojo JP, Valdez H, Dhople VM, Lamberti Y, Völker U, Rodriguez ME Tags: J Proteomics Source Type: research
Bordetella pertussis in School-Age Children, Adolescents, and Adults: A Systematic Review of Epidemiology, Burden, and Mortality in Africa
In conclusion, the highest burden of pertussis in Africa is amon g infants, and surveillance is lacking in many African countries meaning that the burden of pertussis among infants and infection rates among older children and adults are not well reported, and likely underestimated.
Source: Infectious Diseases and Therapy - April 21, 2021 Category: Infectious Diseases Source Type: research
Bordetella pertussis in School-Age Children, Adolescents, and Adults: A Systematic Review of Epidemiology, Burden, and Mortality in the Middle East
AbstractDespite modern diphtheria-tetanus-pertussis (DTP) vaccines and high vaccine coverage, a resurgence of pertussis (whooping cough) has been observed globally. In North America and Europe, high vaccine coverage in children has led to a shift in the age-specific peak incidence of infection away from infants and towards older children and adolescents. However, much less is known about the prevalence of pertussis in older children and adults in the Middle East. A systematic search of MEDLINE, EMBASE, and BIOSIS was undertaken to identify studies published between 1 January 1990 and 17 June 2019, with information on pertu...
Source: Infectious Diseases and Therapy - April 27, 2021 Category: Infectious Diseases Source Type: research
Bordetella pertussis in School-Age Children, Adolescents, and Adults: A Systematic Review of Epidemiology, Burden, and Mortality in Asia
AbstractCyclic epidemics of pertussis (whooping cough) have been observed globally over the past twenty years despite high infant vaccine coverage. The resurgence of pertussis in high-income countries is partly due to waning vaccine immunity in older children and adults, as well as better surveillance and diagnostics. Moreover, in adolescents and adults, pertussis symptoms are mild and similar to common cough syndromes, meaning that it is under-diagnosed in older populations. A systematic search of MEDLINE, EMBASE, and BIOSIS was undertaken to identify studies published between 1 January 1990 and 17 June 2019, with info...
Source: Infectious Diseases and Therapy - April 29, 2021 Category: Infectious Diseases Source Type: research
Vaccination in Pregnancy
CONCLUSION: Maternal immunization is a safe and effective strategy for giving neo - nates passive immune protection against life-threatening infections by the vertical transmission of maternal antibodies until they are able to build up their own adaptive immunity.PMID:34114547 | DOI:10.3238/arztebl.m2021.0020
Source: Deutsches Arzteblatt International - June 11, 2021 Category: General Medicine Authors: Marianne R öbl-Mathieu Ariane Kunstein Johannes Liese Thomas Mertens Michael Wojcinski Source Type: research
Mucosal Immunization Against Pertussis: Lessons From the Past and Perspectives
ConclusionThree vaccination strategies drew our attention, as they provided protective and durable immunity in the respiratory tract, including the upper respiratory tract: acellular vaccines adjuvanted with lipopeptide LP1569 and c-di-GMP, outer membrane vesicles and the live attenuated BPZE1 vaccine. Among all experimental vaccines, BPZE1 is the only one that has advanced into clinical development.
Source: Frontiers in Immunology - June 15, 2021 Category: Allergy & Immunology Source Type: research
Vaccination in Pregnancy
CONCLUSION: Maternal immunization is a safe and effective strategy for giving neo - nates passive immune protection against life-threatening infections by the vertical transmission of maternal antibodies until they are able to build up their own adaptive immunity.PMID:34114547 | DOI:10.3238/arztebl.m2021.0020
Source: Deutsches Arzteblatt International - June 11, 2021 Category: General Medicine Authors: Marianne R öbl-Mathieu Ariane Kunstein Johannes Liese Thomas Mertens Michael Wojcinski Source Type: research
Adult Vaccination as a Protective Factor for Dementia: A Meta-Analysis and Systematic Review of Population-Based Observational Studies
ConclusionRoutine adult vaccinations are associated with a significant reduction in dementia risk and may be an effective strategy for dementia prevention. Further research is needed to elucidate the causal effects of this association and the underlying mechanisms.
Source: Frontiers in Immunology - May 3, 2022 Category: Allergy & Immunology Source Type: research
Influence of the COVID-19 pandemic and social media on the behaviour of pregnant and lactating women towards vaccination: a scoping review
Discussion and conclusion
Vaccine hesitancy in pregnant and lactating women remains an important issue, expressing the need for effective interventions to increase vaccine confidence and coverage. The role social media plays in vaccine uptake remains unclear.
Source: BMJ Open - February 10, 2023 Category: General Medicine Authors: De Brabandere, L., Hendrickx, G., Poels, K., Daelemans, W., Van Damme, P., Maertens, K. Tags: Open access, Public health, COVID-19 Source Type: research
Barriers to and facilitators of populational adherence to prevention and control measures of COVID-19 and other respiratory infectious diseases: a qualitative evidence synthesis
Conclusions:
This review suggests that financial and social support, assertive communication, trust in political authorities and greater regulation of social media enhance adherence to prevention and control measures for COVID-19 and infectious respiratory diseases. Designing and implementing effective educational public health interventions targeting the findings of barriers and facilitators highlighted in this review are key to reducing the impact of infectious respiratory diseases at the population level.
Source: European Respiratory Review - June 21, 2023 Category: Respiratory Medicine Authors: Zaildo, T., Santino, T. A., Chaves, G., da Silva, B. A. K., Alchieri, J. C., Patino, C. M., Leite, S., Luz, K. G., Guerra, R. O., da Penha, T. H. S., da Silva, G. R., Jacome, A. C., Monteiro, K. S., de Mendonca, K. M. P. P. Tags: Respiratory infections and tuberculosis Reviews Source Type: research
Investigation of a pertussis outbreak and comparison of two acellular booster pertussis vaccines in a junior school in South East England, 2019
Euro Surveill. 2021 Mar;26(12):2000244. doi: 10.2807/1560-7917.ES.2021.26.12.2000244.ABSTRACTIn March 2019, a pertussis outbreak occurred in children in a junior school (7-11 years) in England who had been offered pertussis-containing booster vaccine at 40 months of age. In a case-control investigation, we assessed the extent of transmission and any difference in protection afforded to those who had previously received a booster 3- or 5-component acellular pertussis vaccine (aP). We took oral fluid specimens from the students to determine IgG antibodies against pertussis toxin (anti-PT). Parents of students attending the s...
Source: Euro Surveill - March 26, 2021 Category: Infectious Diseases Authors: Elise Tessier Helen Campbell Sonia Ribeiro Nick Andrews Julia Stowe Margot Nicholls Jaime Morgan David Litt Norman K Fry Gayatri Amirthalingam Source Type: research
Immunity to vaccine-preventable diseases among paediatric healthcare workers in Denmark, 2019
ConclusionThe immunity gaps found primarily in young HCW indicate a need for a screening and vaccination strategy for this group. Considering the poor correlation between self-reported immunity and seropositivity, efforts should be made to check HCW's immune status in order to identify those who would benefit from vaccination.PMID:33928900 | PMC:PMC8086246 | DOI:10.2807/1560-7917.ES.2021.26.17.2001167
Source: Euro Surveill - April 30, 2021 Category: Infectious Diseases Authors: Marie-Louise von Linstow Alex Yde Nielsen Nikolai Kirkby Anna Eltvedt Thilde Nordmann Winther Allan Bybeck Nielsen Didi Bang Anja Poulsen Source Type: research
