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A review of neurological side effects of COVID-19 vaccination
AbstractFollowing the COVID-19 virus epidemic, extensive, coordinated international research has led to the rapid development of effective vaccines.  Although vaccines are now considered the best way to achieve collective safety and control mortality, due to the critical situation, these vaccines have been issued the emergency use licenses and some of their potential subsequence side effects have been overlooked. At the same time, there are many reports of side effects after getting a COVID-19 vaccine. According to these reports, vaccination can have an adverse event, especially on nervous system. The most important a...
Source: European Journal of Medical Research - February 25, 2023 Category: Research Source Type: research

A Systematic Review and Meta-Analysis of the Relationship between Receiving the Flu Vaccine with Acute Cerebrovascular Accident and Its Hospitalization in the Elderly
CONCLUSION: Getting the flu vaccine can reduce the risk of occurrence and hospitalization of stroke in the elderly by 16% (10%-22%). Therefore, receiving this vaccine as a preventive intervention for stroke in the elderly may be promising.PMID:36814798 | PMC:PMC9940958 | DOI:10.1155/2023/2606854
Source: Biomed Res - February 23, 2023 Category: Research Authors: Nilay Rezaei Tavabe Soleiman Kheiri Mohsen Dehghani Abdollah Mohammadian-Hafshejani Source Type: research

Mayo Clinic Minute: Flu vaccine may reduce risk of stroke
Getting a flu shot may offer an added benefit. A recent study published in Stroke, an American Heart Association journal, suggests flu vaccination might lower the chances of stroke among adults, especially people under 45. Dr. Gyanendra Kumar, a Mayo Clinic neurologist not involved in the study, says it's long been known that respiratory infections increase the risk of stroke in the days following infection. Watch: The Mayo Clinic Minute https://youtu.be/RuTvvyd_A24 Journalists: Broadcast-quality video pkg (1:00) is in the downloads at the end of the…
Source: Mayo Clinic Research News - October 24, 2022 Category: Research Source Type: news

Hyperviscosity syndrome in COVID-19 and related vaccines: exploring of uncertainties
In conclusion, COVID-19 and related vaccines are linked with the development of HVS, mainly in patients with previous COVID-19 and underlying metabolic derangements. The possible mechanism of HVS in COVID-19 and related vaccines is increasing levels of fibrinogen and immunoglobulins. However, dehy dration, oxidative stress, and inflammatory reactions are regarded as additional contributing factors in the pathogenesis of HVS in COVID-19. However, this critical review cannot determine the final causal relationship between COVID-19 and related vaccines and the development of HVS. Prospective and retrospective studies are warranted in this field.
Source: Clinical and Experimental Medicine - May 24, 2022 Category: Research Source Type: research

SARS-CoV-2: Pathogenic Mechanisms and Host Immune Response
Adv Exp Med Biol. 2021;1313:99-134. doi: 10.1007/978-3-030-67452-6_6.ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense RNA coronavirus responsible for the COVID-19 pandemic. Since December 2019, coronavirus disease 2019 (COVID-19) has affected more than 127 million people, 2.7 million deaths globally (as per WHO dashboard, dated 31 March, 2020), the virus is capable of transmitting from human to human via inhalation of infected respiratory droplets or aerosols or contact with infected fomites. Clinically, patients with COVID-19 present with severe respiratory distress synd...
Source: Advances in Experimental Medicine and Biology - October 18, 2021 Category: Research Authors: Hadida Yasmin Sudipta Saha Mariam Tariq Butt Rishab Kumar Modi Andrew J T George Uday Kishore Source Type: research

A cluster randomized controlled trial comparing relative effectiveness of two licensed influenza vaccines in US nursing homes: Design and rationale.
CONCLUSIONS: This high-dose influenza vaccine trial uniquely offers a paradigm for future studies of clinical and programmatic interventions within the framework of efforts designed to test the impact of changes in usual treatment practices adopted by health care systems. TRIAL REGISTRATION: NCT01815268. PMID: 26908539 [PubMed - as supplied by publisher]
Source: Clinical Trials - February 11, 2016 Category: Research Authors: Gravenstein S, Dahal R, Gozalo PL, Davidson HE, Han LF, Taljaard M, Mor V Tags: Clin Trials Source Type: research

Ixodes scapularis Tissue Factor Pathway Inhibitor
Ixodes scapularis is a blood-sucking tick and the principal vector of Lyme disease, a spirochetal illness caused by Borrelia burgdorferi and now the most common vector-borne infection in the United States; more than 50,000 cases have been reported during the last ten years. The salivary gland of I. scapularis has a number of pharmacologically active molecules that help the tick to successfully feed on blood, such as inhibitors of complement system, in addition to coagulation and platelet aggregation inhibitors. This invention describes Ixolaris, a protein that inhibits the initiation of blood coagulation by inhibition of c...
Source: NIH OTT Licensing Opportunities - December 1, 2000 Category: Research Authors: admin Source Type: research