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Specialty: Neurology
Procedure: Perfusion
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Total 1377 results found since Jan 2013.
Preliminary Application of a Quantitative Collateral Assessment Method in Acute Ischemic Stroke Patients With Endovascular Treatments: A Single-Center Study
Conclusion: The quantitative evaluation of collateral circulation on tMIP CTA is associated with clinical outcomes in AIS patients with endovascular treatments.
Source: Frontiers in Neurology - December 23, 2021 Category: Neurology Source Type: research
Association Between CT Angiogram Collaterals and CT Perfusion in Delayed Time Windows for Large Vessel Occlusion Ischemic Strokes
Recent endovascular trials have established the use of CT perfusion (CTP) in endovascular treatment selection for patients with large vessel occlusions (LVO). However, the relationship between CTP and collateral circulation is unclear in delayed time windows. We explored the relationship between CT Angiogram (CTA) collaterals and CTP parameters in delayed time windows (6-24 hours).
Source: Journal of Stroke and Cerebrovascular Diseases - December 23, 2021 Category: Neurology Authors: Sriharsha Voleti, Yasmin N Aziz, Johnathan Vidovich, Brendan Corcoran, Bin Zhang, Eva Mistry, Vivek Khandwala, Pooja Khatri, Thomas Tomsick, Lily Wang, Abdelkader Mahammedi, Achala Vagal Source Type: research
Real-World Cost-Effectiveness of Late Time Window Thrombectomy for Patients With Ischemic Stroke
Conclusions: Treating patients not meeting the DAWN or DEFUSE 3 clinical trial criteria in the extended time window for EVT was associated with less gain in QALYs and higher cost. Caution should be exercised when considering this procedure for patients not satisfying the trial perfusion imaging criteria for EVT.
Source: Frontiers in Neurology - December 14, 2021 Category: Neurology Source Type: research
Association of Multiple Passes during Mechanical Thrombectomy with Incomplete Reperfusion and Lesion Growth
Conclusions: Our findings suggest that incomplete reperfusion on post-EVT MRI is present even in some patients with successful recanalization at the time of EVT and is associated with multiple-pass thrombectomy, lesion growth, and worse outcome. Future studies are needed to investigate whether patients with residual hypoperfusion may benefit from immediate adjunctive therapy to limit lesion growth and improve clinical outcome.Cerebrovasc Dis
Source: Cerebrovascular Diseases - December 13, 2021 Category: Neurology Source Type: research
Caveats to Acute Imaging for Acute Stroke in the Setting of Venoarterial Extracorporeal Membrane Oxygenation
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for cardiorespiratory support in medically refractory cases. The high rate of neurologic complications, specifically cerebrovascular disorders such as acute ischemic stroke, in VA-ECMO patients frequently prompts the acquisition of neuroimaging studies such as CT with angiography and perfusion imaging. Clinicians must be familiar with the ECMO-related artifacts when interpreting such studies. Here, we describe a case of asymmetric contrast opacification in a VA-ECMO patient with axillary artery cannulation.
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Viamonte, M. A., Yu, J., Echevarria, F. D., Nagae, L., Youn, T. S., Tahsili-Fahadan, P., Simpkins, A. N. Tags: Stroke in young adults, CT, All Cerebrovascular disease/Stroke Case Source Type: research
Clinical characteristics and perfusion-computed tomography alterations in a series of patients with migraine with aura attended as stroke code
CONCLUSION: This is, to the best of our knowledge, the largest series of patients with MA managed as presumed stroke with clinical characteristics and PCT. In our study, most patients were young and had a prior history of migraine. PCT was normal in 88% of cases, with patients being still symptomatic by the time they were scanned. Further research will clarify the presence and type of PCT alterations in this entity.PMID:34862603 | DOI:10.1111/head.14243
Source: Headache - December 4, 2021 Category: Neurology Authors: Alicia Gonzalez-Martinez Santiago Trillo Sen ín Carmen Benavides Bernaldo de Queir ós Laura Casado Fern ández Antonio Barbosa Del Olmo Rafael Manzanares L ópez Ana Beatriz Gago-Veiga Jos é Vivancos Source Type: research
Telestroke Assessment With Perfusion CT Improves the Diagnostic Accuracy of Stroke vs. Mimic
Conclusions: In the telehealth setting, the absence of an ischaemic lesion on CTP adds to the diagnostic accuracy in distinguishing mimic from stroke, above that from clinical features.
Source: Frontiers in Neurology - December 3, 2021 Category: Neurology Source Type: research
Cost-Consequence Analysis of Advanced Imaging in Acute Ischemic Stroke Care
Conclusions: Our study reveals that adoption of advanced CTAP imaging at presentation increases the demand for treatment of acute ischemic stroke patients as more patients are diagnosed within the treatment time window compared to standard-of-care imaging. Advanced imaging also leads to more patients with good functional outcomes and fewer patients with dependent functional status.
Source: Frontiers in Neurology - November 26, 2021 Category: Neurology Source Type: research
Perfusion Imaging Collateral Scores Predict Infarct Growth in Non-Reperfused DEFUSE 3 Patients
This study evaluated the associations of perfusion imaging collateral profiles with radiographic and clinical outcome in late presenting, non-reperfused patients in the DEFUSE 3 clinical trial.
Source: Journal of Stroke and Cerebrovascular Diseases - November 22, 2021 Category: Neurology Authors: Adam MacLellan, Michael Mlynash, Stephanie Kemp, Santiago Ortega-Gutierrez, Jeremy J. Heit, Michael P. Marks, Maarten G. Lansberg, Gregory W. Albers, DEFUSE 3 Investigators Source Type: research
Multimodal CT Imaging Characteristics in Predicting Prognosis of Wake-Up Stroke
Conclusions:Penumbra volume and collateral score are the most relevant baseline imaging characters in predicting outcome of WUS patients. These imaging characteristics might be instructive to treatment selection. As the small sample size of current study, further studies with larger sample size are needed to confirm these observations.
Source: Frontiers in Neurology - November 15, 2021 Category: Neurology Source Type: research
De Novo Cerebral Microbleeds and Cognitive Decline in Cerebral Hyperperfusion After Direct Revascularization for Adult Moyamoya Disease
Adult patients with moyamoya disease (MMD) occasionally develop cognitive decline due to cerebral hyperperfusion following direct revascularization surgery. However, how the hyperperfusion phenomenon contributes to declines in cognitive function remains unclear. The present supplementary analysis of a prospective study aimed to determine whether cerebral hyperperfusion following direct revascularization surgery for adult MMD with ischemic presentation and misery perfusion leads to development of de novo cerebral microbleeds (CMBs) and whether postoperative cognitive decline is related to these CMBs.
Source: Journal of Stroke and Cerebrovascular Diseases - November 9, 2021 Category: Neurology Authors: Kazumasa Dobashi, Yoshitaka Kubo, Kazuto Kimura, Yasukazu Katakura, Kohei Chida, Masakazu Kobayashi, Kenji Yoshida, Shunrou Fujiwara, Kazunori Terasaki, Kuniaki Ogasawara Source Type: research
Noncontrast CT vs CT Perfusion or MRI Selection in Late Presentation of Large-Vessel –Occlusion Stroke
This cohort study compares the clinical outcomes of patients with stroke who presented 6 to 24 hours after symptom onset and were selected for mechanical thrombectomy by noncontrast computed tomography vs those selected by computed tomography perfusion or magnetic resonance imaging.
Source: JAMA Neurology - November 8, 2021 Category: Neurology Source Type: research
Ischemic Penumbra: A Personal View
The concept of the ischemic penumbra was defined over 40 years ago by Lindsay Symon and his group and is now an established principle of all acute ischemic stroke therapies. These reperfusion treatments rescue threatened, critically hypoperfused brain tissue and have been proven to improve clinical outcomes. We have been fortunate to have observed and played a small part in the penumbral story from its beginnings in the 1970s to its pivotal position today. Over this period, we have witnessed penumbral imaging evolve from positron emission tomography through to magnetic resonance imaging and now predominantly computed tomog...
Source: Cerebrovascular Diseases - November 4, 2021 Category: Neurology Source Type: research
