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Therapy: Cardiac Resynchronization Therapy

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Total 150 results found since Jan 2013.

Echocardiography and cardiac resynchronization therapy
Publication date: Available online 12 September 2015 Source:Cor et Vasa Author(s): Josef Marek, Jana Gandalovičová, Eva Kejřová, Miroslav Pšenička, Aleš Linhart, Tomáš Paleček Cardiac resynchronization therapy (CRT) is an effective therapeutic option in patients with congestive heart failure, left ventricular ejection fraction≤35%, and a widened QRS complex. However, a significant proportion of individuals do not respond to CRT favorably. Understandably, a large number of studies have addressed various techniques to improve patient selection for CRT and to improve responder rate in patients with CRT dev...
Source: Cor et Vasa - September 12, 2015 Category: Cardiology Source Type: research

Letter by Cacko, et al Regarding Article, "Improvement of Cardiac Function by Increasing Stimulus Strength During Left Ventricular Pacing in Cardiac Resynchronization Therapy".
Authors: Cacko A, Michalak M, Główczyńska R, Kochanowski J, Grabowski M Abstract Dear Editor,We have read with great interest the article discussing an improvement of cardiac function by increasing stimulus strength during left ventricular pacing in cardiac resynchronization therapy (CRT) by Ishibashi, et al.(1)) The authors investigated whether increasing stimulus strength of left ventricle (LV) pacing improves LV mechanical dyssynchrony and cardiac function in patients treated with CRT. According to their observation higher stimulus strength may result in statistically significant decreases in QRS duration, se...
Source: International Heart Journal - September 16, 2015 Category: Cardiology Tags: Int Heart J Source Type: research

A Pilot Study Assessing ECG vs. ECHO Ventriculo‐Ventricular Optimization in Pediatric Resynchronization Patients
Conclusion: ECHO optimization of synchrony was not superior to ECG optimization in this pilot study. ECG optimization required less time and cost than ECHO optimization.This article is protected by copyright. All rights reserved
Source: Journal of Cardiovascular Electrophysiology - October 30, 2015 Category: Cardiology Authors: RAJESH PUNN, DEBRA HANISCH, KARA S. MOTONAGA, DAVID N. ROSENTHAL, SCOTT R. CERESNAK, ANNE M. DUBIN Tags: Original Article Source Type: research

Non-invasive hemodynamic analysis in cardiac resynchronization therapy patients wearing quadripolar left ventricular leads: the importance of pacing electrode selection.
CONCLUSION: Our study demonstrates that different bipolar pacing configurations, even if arising from a single CS branch, substantially modify the hemodynamic effect of LV pacing in CRT patients. Moreover, the non-invasive hemodynamic analysis suggests the better pacing configuration should be established individually and could represent an important issue in optimizing CRT during follow-up. PMID: 25275712 [PubMed - indexed for MEDLINE]
Source: Minerva Cardioangiologica - November 18, 2015 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Dynamic Changes in High‐Sensitivity Cardiac Troponin I Are Associated with Dynamic Changes in Sum Absolute QRST Integral on Surface Electrocardiogram in Acute Decompensated Heart Failure
ConclusionPatient‐specific time‐varying changes in the surface ECG scalar measure of global electrical heterogeneity, as measured by SAI QRST, and in myocardial injury as measured by hsTnI, are independently and directly associated with each other, likely reflecting a common underlying mechanism.
Source: Annals of Noninvasive Electrocardiology - June 5, 2016 Category: Cardiology Authors: Larisa G. Tereshchenko, Albert Feeny, Erica Shelton, Thomas Metkus, Andrew Stolbach, Ernest Mavunga, Shannon Putman, Frederick K. Korley Tags: Original Article Source Type: research

Changes in Implantation Patterns and Therapy Rates of Implantable Cardioverter Defibrillators over Time in Ischemic and Dilated Cardiomyopathy Patients
ConclusionThese changes in clinical practice with a shift to primary prevention and rise in non‐ICM implants caused a significant decrease in AS incidence, while IAS remained stable. Receiving AS or IAS was not an independent predictor of mortality in our real‐life cohort.
Source: Pacing and Clinical Electrophysiology : PACE - June 6, 2016 Category: Cardiology Authors: BERT VANDENBERK, CHRISTOPHE GARWEG, GABOR VOROS, VINCENT FLORÉ, THOMAS MARYNISSEN, CHRISTIAN STICHERLING, MARKUS ZABEL, JORIS ECTOR, RIK WILLEMS Tags: ORIGINAL Source Type: research

Bifocal left ventricular stimulation or the optimal left ventricular stimulation site in cardiac resynchronization therapy: a pressure-volume loop study
Conclusion Stimulation at the optimal LV site showed a significantly higher pump function improvement compared with bifocal LV stimulation. Mechanical activation at the optimal LV site was significantly more delayed compared with the non-optimal LV site. In general, these results suggest that implantation of a second LV lead yields no additional benefit over implantation of one optimally placed LV lead. However, a bifocal approach might be beneficial in the individual patient.
Source: Europace - June 28, 2016 Category: Cardiology Authors: de Roest, G. J., Wu, L., de Cock, C. C., Delnoy, P.-P. H. M., Hendriks, M. L., van Rossum, A. C., Allaart, C. P. Tags: Pacing and resynchronization therapy Source Type: research

Mortality After Atrioventricular Nodal Radiofrequency Catheter Ablation With Permanent Ventricular Pacing in Atrial Fibrillation: Outcomes From a Controlled Nonrandomized Study Original Article
Conclusions— In sick AF patients with multiple comorbidities, AVNA with permanent ventricular pacing for rate control seems safe during follow-up and may be associated with lower mortality.
Source: Circulation: Arrhythmia and Electrophysiology - June 29, 2016 Category: Cardiology Authors: Garcia, B., Clementy, N., Benhenda, N., Pierre, B., Babuty, D., Olshansky, B., Fauchier, L. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Original Article Source Type: research

Dynamic Changes in High ‐Sensitivity Cardiac Troponin I Are Associated with Dynamic Changes in Sum Absolute QRST Integral on Surface Electrocardiogram in Acute Decompensated Heart Failure
ConclusionPatient‐specific time‐varying changes in the surface ECG scalar measure of global electrical heterogeneity, as measured by SAI QRST, and in myocardial injury as measured by hsTnI, are independently and directly associated with each other, likely reflecting a common underlying mechanism.
Source: Annals of Noninvasive Electrocardiology - June 5, 2016 Category: Cardiology Authors: Larisa G. Tereshchenko, Albert Feeny, Erica Shelton, Thomas Metkus, Andrew Stolbach, Ernest Mavunga, Shannon Putman, Frederick K. Korley Tags: Original Article Source Type: research

Gauging the response to cardiac resynchronization therapy: The important interplay between predictor variables and definition of a favorable outcome
ConclusionThe definition of a favorable CRT response influenced the optimal predictor variable(s). Standardization of defining a favorable response to CRT is needed to guide clinical decision making processes.
Source: Echocardiography - January 10, 2017 Category: Cardiology Authors: Milan Petrovic, Marija Petrovic, Goran Milasinovic, Bosiljka Vujisic Tesic, Danijela Trifunovic, Olga Petrovic, Ivana Nedeljkovic, Ivana Petrovic, Marko Banovic, Marija Boricic ‐Kostic, Jelena Petrovic, Ross Arena, Dejana Popovic Tags: ORIGINAL INVESTIGATION Source Type: research

Atrioventricular dyssynchrony from empiric device settings is common in cardiac resynchronization therapy and adversely impacts left ventricular morphology and function
ConclusionOur study suggests that up to 50% of patients with empiric device settings have AV dyssynchrony at 6 months despite atrioventricular delay optimization (AVO) algorithms. As AV dyssynchrony is common and has proven to be modifiable, a strategic approach to Doppler echocardiography‐guided AVO after CRT is warranted, particularly in nonresponders where the LV filling pattern is fused or truncated.
Source: Echocardiography - February 28, 2017 Category: Cardiology Authors: Gregory J. Sinner, Vedant A. Gupta, Arash Seratnahaei, Richard J. Charnigo, Yousef H. Darrat, Samy C. Elayi, Steve W. Leung, Vincent L. Sorrell Tags: ORIGINAL INVESTIGATION Source Type: research

Heart rate and dyssynchrony in patients with cardiac resynchronization therapy: a pilot study.
The objective of this pilot study was to describe the impact of paced heart rate on left ventricular (LV) mechanical dyssynchrony in synchronous compared to dyssynchronous pacing modes in patients with heart failure. METHODS: Echocardiography was performed in 14 cardiac resynchronization therapy (CRT) patients at paced heart rates of 70 and 90 bpm in synchronous- (CRT), and dyssynchronous (atrial pacing + wide QRS activation) pacing modes. LV dyssynchrony was quantified using the 12-segment standard deviation model (Ts-SD) derived from Tissue Doppler Imaging. In addition, cardiac cycle intervals were assessed using...
Source: Scandinavian Cardiovascular Journal - March 27, 2017 Category: Cardiology Tags: Scand Cardiovasc J Source Type: research

Clinical implications of long term ECG monitoring: from loop recorder to devices remote control.
Authors: DI Cori A, DE Lucia R Abstract Long term ECG monitoring has become nowadays an indispensable technology for prevention, management and treatment of many cardiac issues. Today long term ECG monitoring is achievable through loop recorders (LR) and cardiac devices (CIED) like pacemaker (PM), implantable cardioverter-defibrillators (ICDs) and cardiac resynchronization therapy device-defibrillators (CRT- Ds), all of which associated with remote monitoring (RM). Targeted long term ECG monitoring Patients who have recurrent non documented episodes of palpitations, unexplained episodes of syncope, cryptogenic stro...
Source: Minerva Cardioangiologica - July 20, 2017 Category: Cardiology Tags: Minerva Cardioangiol Source Type: research

Improved patient selection for cardiac resynchronization therapy by normalization of QRS duration to left ventricular dimension
ConclusionSince normalized QRSd reflects myocardial conduction properties, these findings suggest that myocardial conduction velocity rather than increased path length mainly determines response to CRT. Normalizing QRSd to LV dimension might provide a relatively simple method to improve patient selection for CRT.
Source: Europace - October 5, 2016 Category: Cardiology Source Type: research

Heart failure study of multipoint pacing effects on ventriculoarterial coupling: Rationale and design of the HUMVEE trial
Cardiac resynchronization therapy (CRT) is an established therapy for symptomatic heart failure (HF). Unfortunately, many recipients remain nonresponders. Studies have revealed the potential role of multipoint pacing (MPP) in improving response and outcomes. The aim of this study is to compare the effects of MPP against those of standard biventricular pacing (BVP) on (i) ventriculoarterial coupling (VAC) and energy efficiency of the failing heart, (ii) diastolic function, (iii) quality of life, and (iv) NT‐proBNP levels and glomerular filtration rate (GFR) during a follow‐up of 13 months. HUMVEE is a single‐center, ...
Source: Annals of Noninvasive Electrocardiology - October 15, 2017 Category: Cardiology Authors: Christina Chrysohoou, Polychronis Dilaveris, Christos ‐Konstantinos Antoniou, Ioannis Skiadas, Konstantinos Konstantinou, Konstantinos Gatzoulis, Ioannis Kallikazaros, Dimitrios Tousoulis Tags: ORIGINAL ARTICLE Source Type: research