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Total 6766 results found since Jan 2013.

Too Much and Too Little: Antidepressant Treatment in Stroke Survivors during the First Year
CONCLUSIONS: Depression occurred in one in three stroke survivors. Among these, only one in two received ADT, irrespective of PSD severity after discharge. In contrast, one in eight stroke survivors without depressive disorder received ADT, about half of them in the absence of earlier PSD. In conclusion, we found evidence of both under- and overtreatment of PSD with ADT, which emphasizes the need for a more stringent implementation of current PSD guideline recommendations.PMID:35864760 | DOI:10.31083/j.jin2104108
Source: Journal of Integrative Neuroscience - July 22, 2022 Category: Neuroscience Authors: Katja Werheid Matthias Volz Simon Ladwig Maree Hackett Source Type: research

Symptoms and pattern of symptom propagation in incipient ischemic stroke and migraine aura
ConclusionThere is a significant overlap in the clinical presentation of stroke and migraine aura. In particular, a substantial proportion of patients in one group had symptoms that are traditionally attributed to the other group. This study highlights the similarities and differences between symptoms of ischemic stroke and migraine aura and challenges our reasoning in daily clinical practice.
Source: Frontiers in Human Neuroscience - January 13, 2023 Category: Neuroscience Source Type: research

Association of serum uric acid to lymphocyte ratio, a novel inflammatory biomarker, with risk of stroke: A prospective cohort study
CONCLUSIONS: ULR was significantly associated with the risk of HS, but not with IS. Systolic blood pressure, diastolic blood pressure and estimated glomerular filtration rate were potential mediators for the association.PMID:36650955 | DOI:10.1111/cns.14094
Source: CNS Neuroscience and Therapeutics - January 18, 2023 Category: Neuroscience Authors: Xue Tian Penglian Wang Shuohua Chen Yijun Zhang Xiaoli Zhang Qin Xu Yanxia Luo Shouling Wu Anxin Wang Source Type: research

Impact of the COVID-19 pandemic on acute stroke care: An  analysis of the 24-month data from a comprehensive stroke center in Shanghai, China
CONCLUSIONS: During the 24 months of COVID-19, a prolongation of stroke onset to hospital arrival and to intravenous rt-PA administration times were noted. Meanwhile, acute stroke patients needed to stay in the ED for a longer time before hospitalization. Educational system support and process optimization should be pursued in order to acquire timely delivery of stroke care during the pandemic.PMID:36890633 | DOI:10.1111/cns.14148
Source: CNS Neuroscience and Therapeutics - March 8, 2023 Category: Neuroscience Authors: Qimin Hu Yiming Hu Yue Gu Xiaoyan Song Yijue Shen Haiyan Lu Li Zhang Peifeng Liu Guodong Wang Chunni Guo Kan Fang Qiaoshu Wang Source Type: research

Trends in NLRP3 inflammasome research in ischemic stroke from 2011 to 2022: A bibliometric analysis
CONCLUSION: This study is a scientometric study utilizing quantitative and qualitative methods to comprehensively review the publications on NLRP3 in ischemic stroke. This information provides a reference for scholars to further study NLRP3 in ischemic stroke.PMID:37088947 | DOI:10.1111/cns.14232
Source: CNS Neuroscience and Therapeutics - April 23, 2023 Category: Neuroscience Authors: Hua Zhu Yonggang Zhang Shi Feng Yina Li Yingze Ye Zhihong Jian Xiaoxing Xiong Lijuan Gu Source Type: research

Dense dopaminergic innervation of the peri ‐infarct cortex despite dopaminergic cell loss after a pure motor‐cortical stroke in rats
In this study, we assessed the reorganization of dopaminergic innervation of the PIC in a rat model of focal cortical stroke. Our data suggest a sprouting of dopaminergic fibers into the PIC and point to a role for dopaminergic signaling in reparative mechanisms post-stroke, potentially related to recovery. AbstractAfter ischemic stroke, the cortex directly adjacent to the ischemic core (i.e., the peri-infarct cortex, PIC) undergoes plastic changes that facilitate motor recovery. Dopaminergic signaling is thought to support this process. However, ischemic stroke also leads to the remote degeneration of dopaminergic midbrai...
Source: Journal of Neurochemistry - September 22, 2023 Category: Neuroscience Authors: Sibylle Frase, Julius Steddin, Enya Paschen, Maximilian Lenz, Pasquale Conforti, Carola A. Haas, Andreas Vlachos, Christian Schachtrup, Jonas A. Hosp Tags: ORIGINAL ARTICLE Source Type: research

State of intracortical inhibitory interneuron activity in patients with chronic stroke
Conclusions: The state of intracortical inhibitory neuron activity depends on the state of motor function and lesion site even in chronic stroke patients with severe hemiparesis.Significance: The inhibitory system of the AH is involved in functional recovery of the paretic hand even in the chronic stage of stroke.
Source: Clinical Neurophysiology - September 5, 2012 Category: Neuroscience Authors: Kaoru Honaga, Toshiyuki Fujiwara, Tetsuya Tsuji, Kimitaka Hase, Junichi Ushiba, Meigen Liu Tags: Movement, Motor Control and Movement Disorders Source Type: research

Neuron Specific Enolase and C-reactive Protein Levels in Stroke and Its Subtypes: Correlation with Degree of Disability.
Abstract Stroke is an emergency which threatens life and third leading cause of death and long term disability in developed countries. The use of biomarkers in diagnosing stroke and assessing prognosis is an emerging and rapidly evolving field. The study aimed to investigate the predictive value of biochemical marker of brain damage neuron-specific enolase (NSE) and systemic inflammatory marker C-reactive protein (CRP) with respect to degree of disability at the time of admission and short term in stroke patients. We investigated 120 patients with cerebrovascular stroke who were admitted within 72 h of onset of s...
Source: Neurochemical Research - May 17, 2014 Category: Neuroscience Authors: Pandey A, Shrivastava AK, Saxena K Tags: Neurochem Res Source Type: research