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Nutrition: Diets

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Total 303 results found since Jan 2013.

Heart Disease and Stroke Statistics-2022 Update: A Report From the American Heart Association
CONCLUSIONS: The Statistical Update represents a critical resource for the lay public, policymakers, media professionals, clinicians, health care administrators, researchers, health advocates, and others seeking the best available data on these factors and conditions.PMID:35078371 | DOI:10.1161/CIR.0000000000001052
Source: Circulation - January 26, 2022 Category: Cardiology Authors: Connie W Tsao Aaron W Aday Zaid I Almarzooq Alvaro Alonso Andrea Z Beaton Marcio S Bittencourt Amelia K Boehme Alfred E Buxton April P Carson Yvonne Commodore-Mensah Mitchell S V Elkind Kelly R Evenson Chete Eze-Nliam Jane F Ferguson Giuliano Generoso Jen Source Type: research

Imaging High-Risk Atherothrombosis Using a Novel Fibrin-Binding Positron Emission Tomography Probe
CONCLUSIONS: We demonstrated that molecular fibrin PET imaging using 68Ga-CM246 could be a useful tool to diagnose experimental and clinical atherothrombosis. Based on our initial results using human carotid plaque specimens, in vivo molecular imaging studies are warranted to test 68Ga-CM246 PET as a tool to stratify risk in atherosclerotic patients.PMID:34965737 | DOI:10.1161/STROKEAHA.121.035638
Source: Atherosclerosis - December 30, 2021 Category: Cardiology Authors: David Izquierdo-Garcia Himashinie Diyabalanage Ian A Ramsay Nicholas J Rotile Adam Mauskapf Ji-Kyung Choi Thomas Witzel Valerie Humblet Farouc A Jaffer Anna-Liisa Brownell Ahmed Tawakol Ciprian Catana Mark F Conrad Peter Caravan Ilknur Ay Source Type: research

Diet-induced weight loss in obese/diabetic mice normalizes glucose metabolism and promotes functional recovery after stroke
Post-stroke functional recovery is severely impaired by type 2 diabetes (T2D). This is an important clinical problem since T2D is one of the most common diseases. Because weight loss-based strategies have been...
Source: Cardiovascular Diabetology - December 22, 2021 Category: Cardiology Authors: Dimitra Karampatsi, Alexander Zabala, Ulrika Wilhelmsson, Doortje Dekens, Ellen Vercalsteren, Martin Larsson, Thomas Nystr öm, Milos Pekny, Cesare Patrone and Vladimer Darsalia Tags: Original investigation Source Type: research

Early nutritional influences of cardiovascular health
Expert Rev Cardiovasc Ther. 2021 Dec 18. doi: 10.1080/14779072.2021.2021070. Online ahead of print.ABSTRACTINTRODUCTION: Increasing evidence shows that nutritional choices during children's formative years, including prenatally, impacts the development of adult onset cardiovascular diseases (CVD), such as hypertension, myocardial infarction, or stroke.AREAS COVERED: This literature review aims to synthesize the current body of evidence on nutritional factors, from conception through adolescence, which may influence a person's risk factors for future development of cardiovascular disease.EXPERT OPINION: Given the escalating...
Source: Expert Review of Cardiovascular Therapy - December 20, 2021 Category: Cardiology Authors: Diana Drogalis-Kim Ira Cheifetz Nathaniel Robbins Source Type: research

Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism
Front Cardiovasc Med. 2021 Nov 23;8:768481. doi: 10.3389/fcvm.2021.768481. eCollection 2021.ABSTRACTHigh-fat Western diets contribute to tissue dysregulation of fatty acid and glucose intake, resulting in obesity and insulin resistance and their sequelae, including atherosclerosis. New therapies are desperately needed to interrupt this epidemic. The significant idea driving this research is that the understudied regulation of fatty acid entry into tissues at the endothelial cell (EC) interface can provide novel therapeutic targets that will greatly modify health outcomes and advance health-related knowledge. Dysfunctional ...
Source: Atherosclerosis - December 10, 2021 Category: Cardiology Authors: Umar R Rekhi Mohamed Omar Maria Alexiou Cole Delyea Linnet Immaraj Shokrollah Elahi Maria Febbraio Source Type: research

Identification of Mep1a as a susceptibility gene for atherosclerosis in mice
Genetics. 2021 Sep 29:iyab160. doi: 10.1093/genetics/iyab160. Online ahead of print.ABSTRACTAtherosclerosis is the underlying cause of heart attack, ischemic stroke and peripheral arterial disease, and genetic factors involved remain mostly unidentified. We previously identified a significant locus on mouse chromosome 17 for atherosclerosis, Ath49, in an intercross between BALB/c and SM strains. Ath49 partially overlaps in the confidence interval with Ath22 mapped in an AKR × DBA/2 intercross. Bioinformatics analysis prioritized Mep1a, encoding meprin 1α metalloendopeptidase, as a likely candidate gene for Ath49. To prov...
Source: Atherosclerosis - December 1, 2021 Category: Cardiology Authors: Andrew T Grainger Nathanael Pilar Jun Li Mei-Hua Chen Ashley M Abramson Christoph Becker-Pauly Weibin Shi Source Type: research

Get Your Dietary Fat From Plants, Cut Your Stroke Risk
Title: Get Your Dietary Fat From Plants, Cut Your Stroke RiskCategory: Health NewsCreated: 11/8/2021 12:00:00 AMLast Editorial Review: 11/8/2021 12:00:00 AM
Source: MedicineNet Heart General - November 8, 2021 Category: Cardiology Source Type: news

Pro-Neurotensin/Neuromedin N and Hypertension Risk: a Prospective Study
CONCLUSIONS: Baseline pro-NT/NMN was not associated with incident hypertension. This may be a result of neurotensin's long-term interactions with other molecular regulators of blood pressure, such as the renin-angiotensin-aldosterone system.PMID:34655288 | DOI:10.1093/ajh/hpab166
Source: American Journal of Hypertension - October 16, 2021 Category: Cardiology Authors: C D Nicoli D L Long T B Plante G Howard S E Judd J Schulte M Cushman Source Type: research

Contemporary Medical Management of Peripheral Artery Disease
Circ Res. 2021 Jun 11;128(12):1868-1884. doi: 10.1161/CIRCRESAHA.121.318258. Epub 2021 Jun 10.ABSTRACTPeripheral artery disease (PAD) is a manifestation of systemic atherosclerosis. Modifiable risk factors including cigarette smoking, dyslipidemia, diabetes, poor diet quality, obesity, and physical inactivity, along with underlying genetic factors contribute to lower extremity atherosclerosis. Patients with PAD often have coexistent coronary or cerebrovascular disease, and increased likelihood of major adverse cardiovascular events, including myocardial infarction, stroke and cardiovascular death. Patients with PAD often h...
Source: Circulation Research - June 10, 2021 Category: Cardiology Authors: Marc P Bonaca Naomi M Hamburg Mark A Creager Source Type: research

Altered Properties of Neurons and Astrocytes and the Effects of Food Components in Stroke-Prone Spontaneously Hypertensive Rats
In this study, we obtained information using PubMed, ScienceDirect, and Web of Science. We searched for the functions of neurons and astrocytes and the molecular mechanism of ischemic stroke induction. We summarized the recent literature on the underlying mechanisms of stroke onset in SHRSP and the alleviating effects of typical food-derived phytochemical components. Neuronal death in SHRSP is induced by hypoxia-reoxygenation, suggesting the involvement of oxidative stress. Furthermore, the production of lactate, l-serine, and glial cell line-derived neurotrophic factor in SHRSP-derived astrocytes was reduced compared with...
Source: Journal of Cardiovascular Pharmacology - June 1, 2021 Category: Cardiology Tags: Review Article Source Type: research