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Infectious Disease: Coronavirus
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Total 74541 results found since Jan 2013.
Impact of the early months of the COVID-19 pandemic on the sleep patterns of a Brazilian population sample
Chronobiol Int. 2023 Sep 12:1-13. doi: 10.1080/07420528.2023.2255667. Online ahead of print.ABSTRACTHumanitarian and health crisis have drastic effects on the physical and mental well-being of people. The COVID-19 pandemic forced many countries to impose containment measures on its population to halt the spread of the new coronavirus (SARS-CoV-2). This aim of this study was to explore self-reported sleep quality and insomnia symptoms in a sample of the Brazilian population before and during the COVID-19 quarantine period. Our data was collected through online questionnaires, including the Pittsburgh Sleep Quality Index, th...
Source: Chronobiology International - September 13, 2023 Category: Biology Authors: Sergio Brasil Tufik Gabriel Natan Pires Allan Saj Porcacchia Andr éia Gomes Bezerra Monica Levy Andersen Sergio Tufik Source Type: research
Obtaining a high titer of polyclonal antibodies from rats to the SARS-CoV-2 nucleocapsid protein and its N- and C-terminal domains for diagnostic test development
J Immunol Methods. 2023 Sep 11:113558. doi: 10.1016/j.jim.2023.113558. Online ahead of print.ABSTRACTSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is an enveloped, plus-stranded RNA virus responsible for the Coronavirus Disease 2019 (COVID-19). Patients infected with COVID-19 may be asymptomatic or have symptoms ranging from mild manifestations to severe cases of the disease that could lead to death. The SARS-CoV-2 genome encodes 4 structural proteins, including the Spike protein (S), the Nucleocapsid protein (N), membrane protein (M) and, the envelope (E). The N protein forms a major component of the ribonu...
Source: Journal of Immunological Methods - September 13, 2023 Category: Allergy & Immunology Authors: Michelle Teixeira de Almeida Ana Paula Barbosa Camila Gasque Bomfim Aline Biazola Visnardi Tania Churasacari Vinces Alexandre Ceroni Edison Luiz Durigon Cristiane Rodrigues Guzzo Source Type: research
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation
Curr Opin Immunol. 2023 Sep 11;84:102387. doi: 10.1016/j.coi.2023.102387. Online ahead of print.ABSTRACTCOVID-19 is an infectious and inflammatory disease caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2) that might progress to severe illness in humans, characterized by excessive pulmonary and systemic inflammation. Exacerbated production of inflammatory cytokines and cell death contributes to disease aggravation and the inflammasomes take a central stage in this process. Activation of the NLRP3 has been demonstrated in macrophages and monocytes infected in vitro, in mouse models of infection, and in c...
Source: Current Opinion in Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Tamara S Rodrigues Dario S Zamboni Source Type: research
CROI 2023: Summary of Basic Science Research in HIV
Top Antivir Med. 2023 Jun 30;31(4):523-528.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) represented the first fully in-person conference since the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic began. CROI continues as the premier conference in which delegates can appraise themselves of almost every facet of HIV/AIDS research as well as emerging and re-emerging pathogens such as SARS-CoV-2 and mpox. The return to an in-person format is particularly important for early-stage investigators, who were faced with challenges of advancing their independent research careers...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Mario Stevenson Source Type: research
Obtaining a high titer of polyclonal antibodies from rats to the SARS-CoV-2 nucleocapsid protein and its N- and C-terminal domains for diagnostic test development
J Immunol Methods. 2023 Sep 11:113558. doi: 10.1016/j.jim.2023.113558. Online ahead of print.ABSTRACTSevere Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is an enveloped, plus-stranded RNA virus responsible for the Coronavirus Disease 2019 (COVID-19). Patients infected with COVID-19 may be asymptomatic or have symptoms ranging from mild manifestations to severe cases of the disease that could lead to death. The SARS-CoV-2 genome encodes 4 structural proteins, including the Spike protein (S), the Nucleocapsid protein (N), membrane protein (M) and, the envelope (E). The N protein forms a major component of the ribonu...
Source: Journal of Immunological Methods - September 13, 2023 Category: Allergy & Immunology Authors: Michelle Teixeira de Almeida Ana Paula Barbosa Camila Gasque Bomfim Aline Biazola Visnardi Tania Churasacari Vinces Alexandre Ceroni Edison Luiz Durigon Cristiane Rodrigues Guzzo Source Type: research
Drug use among medical students in S ão Paulo, Brazil: a cross-sectional study during the coronavirus disease 2019 pandemic
CONCLUSION: The prevalence of substance use was high in this population and increased from the basic to the clinical cycle. The COVID-19 pandemic may have affected the frequency of drug use and prevalence estimates.PMID:37703121 | PMC:PMC10495101 | DOI:10.1590/1516-3180.2022.0493.R1.150623
Source: Sao Paulo Medical Journal - September 13, 2023 Category: General Medicine Authors: Pedro Lemos-Santos Lukas Blumrich Jordi Blanes Debia Jo ão Mauricio Castaldelli-Maia Paulo Jeng Chian Suen Andr é Malbergier Source Type: research
CROI 2023: Summary of Basic Science Research in HIV
Top Antivir Med. 2023 Jun 30;31(4):523-528.ABSTRACTThe 2023 Conference on Retroviruses and Opportunistic Infections (CROI) represented the first fully in-person conference since the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic began. CROI continues as the premier conference in which delegates can appraise themselves of almost every facet of HIV/AIDS research as well as emerging and re-emerging pathogens such as SARS-CoV-2 and mpox. The return to an in-person format is particularly important for early-stage investigators, who were faced with challenges of advancing their independent research careers...
Source: Topics in HIV Medicine - September 13, 2023 Category: Infectious Diseases Authors: Mario Stevenson Source Type: research
Inflammasome activation by SARS-CoV-2 and its participation in COVID-19 exacerbation
Curr Opin Immunol. 2023 Sep 11;84:102387. doi: 10.1016/j.coi.2023.102387. Online ahead of print.ABSTRACTCOVID-19 is an infectious and inflammatory disease caused by SARS-CoV-2 (Severe Acute Respiratory Syndrome-Coronavirus-2) that might progress to severe illness in humans, characterized by excessive pulmonary and systemic inflammation. Exacerbated production of inflammatory cytokines and cell death contributes to disease aggravation and the inflammasomes take a central stage in this process. Activation of the NLRP3 has been demonstrated in macrophages and monocytes infected in vitro, in mouse models of infection, and in c...
Source: Current Opinion in Immunology - September 13, 2023 Category: Allergy & Immunology Authors: Tamara S Rodrigues Dario S Zamboni Source Type: research
Drug use among medical students in S ão Paulo, Brazil: a cross-sectional study during the coronavirus disease 2019 pandemic
CONCLUSION: The prevalence of substance use was high in this population and increased from the basic to the clinical cycle. The COVID-19 pandemic may have affected the frequency of drug use and prevalence estimates.PMID:37703121 | PMC:PMC10495101 | DOI:10.1590/1516-3180.2022.0493.R1.150623
Source: Sao Paulo Medical Journal - September 13, 2023 Category: General Medicine Authors: Pedro Lemos-Santos Lukas Blumrich Jordi Blanes Debia Jo ão Mauricio Castaldelli-Maia Paulo Jeng Chian Suen Andr é Malbergier Source Type: research
The impact of COVID-19 related lockdown restrictions on musculoskeletal health: a systematic review
This study was aimed to synthesis literature that assessed the impact of COVID-19 related lockdown restrictions on MSK health. A literature search was conducted using MEDLINE, CINAHL, PsycINFO, Allied and Complementary Medicine Database (AMED), Web of Science, and Scopus databases. Studies meeting the following criteria were included in the review: the condition being considered was MSK health, the intervention was COVID-19 related lockdown restrictions, cross sectional studies, cohort studies, case controlled, prospective studies and retrospective studies. Data were extracted by 2 independent researchers. Risk of bias was...
Source: Rheumatology International - September 12, 2023 Category: Rheumatology Source Type: research
Instagram ' s Threads never wanted to be a platform for hard news or politics. Now it ' s blocking searches about COVID-19
None Users on Threads are unable to search for COVID-19-related terms including "coronavirus" and "vaccines." • None Meta said the block is temporary while it rolls out a new search tool. • None It's the latest sign that Meta is reluctant for Threads to become a place for news and politics. Meta…#nonemeta #meta #threads #twitter #attempts #insidermeta #nathanmcalone #adammosseri #facebookandinstagram
Source: Reuters: Health - September 12, 2023 Category: Consumer Health News Source Type: news
The Impact of COVID19 on Treatment Practices for Patients With Early Breast Cancer: A Cross-Sectional Study From a Large Cancer Center In Italy
CONCLUSIONS: There was no evidence for major changes in the management of patients with EBC during 2019-2021 and no treatment delays were observed. Our findings suggest that more women presented with palpable nodules at diagnosis, but the stage distribution did not change over time. Validation on a larger cohort of patients is warranted to robustly assess the impact of the COVID19 pandemic on treatment practices for patients with EBC.PMID:37699107 | DOI:10.1093/oncolo/oyad255
Source: The Oncologist - September 12, 2023 Category: Cancer & Oncology Authors: Fabio Girardi Sabrina Marini Francesca Porra Sonia Carpentieri Alberto Marchet Tania Saibene Marcello Lo Mele Tommaso Giarratano Carlo Alberto Giorgi Eleonora Mioranza Cristina Falci Giovanni Faggioni Francesca Caumo Gaia Griguolo Maria Vittoria Dieci Val Source Type: research
Influence of Intolerance of Uncertainty on Preoccupation With Coronavirus Disease 2019 Among Frontline Nursing Professionals: Mediating Role of Reassurance-Seeking Behavior and Adherence to Physical Distancing
CONCLUSION: During the pandemic, there may be a strong association between reassurance-seeking behavior, viral anxiety, and a heightened preoccupation with COVID-19 among frontline healthcare workers. Thus, from the early stages of infectious disease, a psychological support team for medical staff responding to the disease should be established, and periodic evaluations should be conducted to identify high-risk groups.PMID:37698207 | PMC:PMC10497351 | DOI:10.3346/jkms.2023.38.e282
Source: J Korean Med Sci - September 12, 2023 Category: General Medicine Authors: Eulah Cho Jihoon Hong Harin Kim C Hyung Keun Park Youjin Hong Jangho Park Jin Yong Jun Seockhoon Chung Source Type: research
