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Infectious Disease: Gastroenteritis
Vaccination: Hepatitis Vaccine

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Total 654 results found since Jan 2013.

Gastrointestinal tract and viral pathogens
World J Virol. 2023 Jun 25;12(3):136-150. doi: 10.5501/wjv.v12.i3.136.ABSTRACTViral gastroenteritis is the most common viral illness that affects the gastrointestinal (GI) tract, causing inflammation and irritation of the lining of the stomach and intestines. Common signs and symptoms associated with this condition include abdominal pain, diarrhea, and dehydration. The infections commonly involved in viral gastroenteritis are rotavirus, norovirus, and adenovirus, which spread through the fecal-oral and contact routes and cause non-bloody diarrhea. These infections can affect both immunocompetent and immunocompromised indiv...
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Gowthami Sai Kogilathota Jagirdhar Yashwitha Sai Pulakurthi Himaja Dutt Chigurupati Salim Surani Source Type: research

Knob domain of Fiber 2 protein provides full protection against fowl adenovirus serotype 4
Virus Res. 2023 Apr 9:199113. doi: 10.1016/j.virusres.2023.199113. Online ahead of print.ABSTRACTHighly pathogenic fowl adenovirus serotype 4 (FAdV-4) is an acute infectious disease with severe economic impact, causing chicken hepatitis hydropericardium syndrome (HHS) and high mortality. In the present study, we evaluated the immunogenicity of the recombinant Fiber2-knob protein (F2-Knob) as an FAdV-4 candidate subunit vaccine in 14-day-old SPF chickens. The knob domain is the functional region of the viral surface protein Fiber2. The protein was expressed in Escherichia coli and was administered a single immunization with...
Source: Virus Research - April 11, 2023 Category: Virology Authors: Yapeng Song Zhenchao Zhao Lin Liu Yifei Li Wenming Gao Xiaonan Song Xinsheng Li Source Type: research

Cost-effectiveness of sub-national geographically targeted vaccination programs: A systematic review
Vaccine. 2023 Feb 11:S0264-410X(23)00132-9. doi: 10.1016/j.vaccine.2023.02.006. Online ahead of print.ABSTRACTImmunization is an essential component of national health plans. However, the growing number of new vaccine introductions, vaccination campaigns and increasing administrative costs create logistic and financial challenges, especially in resource-limited settings. Sub-national geographic targeting of vaccination programs is a potential strategy for governments to reduce the impact of infectious disease outbreaks while optimizing resource allocation and reducing costs, promoting sustainability of critically important...
Source: Vaccine - February 13, 2023 Category: Allergy & Immunology Authors: Marya Getchell Ericka Joinelle Mantaring Kaisin Yee Paul Pronyk Source Type: research

Fight Aging! Newsletter, February 13th 2023
This study investigated whether taller Polish adults live longer than their shorter counterparts. Data on declared height were available from 848,860 individuals who died in the years 2004-2008 in Poland. To allow for the cohort effect, the Z-values were generated. Separately for both sexes, Pearson's r coefficients of correlation were calculated. Subsequently, one way ANOVA was performed. The correlation between adult height and longevity was negative and statistically significant in both men and women. After eliminating the effects of secular trends in height, the correlation was very weak (r = -0.0044 in men and ...
Source: Fight Aging! - February 12, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Expression and Immunogenicity of SARSCoV- 2 Virus-Like Particles based on Recombinant Truncated HEV-3 ORF2 Capsid Protein
J Microbiol Biotechnol. 2022 Sep 19;32(10):1-9. doi: 10.4014/jmb.2205.05023. Online ahead of print.ABSTRACTCOVID-19 is an emerging disease that poses a severe threat to global public health. As such, there is an urgent demand for vaccines against SARS-CoV-2, the virus that causes COVID-19. Here, we describe a virus-like nanoparticle candidate vaccine against SARS-CoV-2 produced by an E. coli expression system. The fusion protein of a truncated ORF2-encoded protein of aa 439~608 (p170) from hepatitis E virus CCJD-517 and the receptor-binding domain of the spike protein from SARSCoV- 2 were expressed, purified and characteri...
Source: Journal of Microbiology and Biotechnology - October 13, 2022 Category: Biotechnology Authors: Yong-Fei Zhou Jiao-Jiao Nie Chao Shi Ke Ning Yu-Feng Cao Yanbo Xie Hongyu Xiang Qiuhong Xie Source Type: research