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Infectious Disease: Gastroenteritis

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Total 46825 results found since Jan 2013.

Alterations and diagnostic performance of capillary ketonemia in pediatric acute appendicitis: a pilot study
ConclusionsThis study found significantly higher levels of CK in patients with PAA than in those with NSAP. Similarly, significantly higher levels were observed in patients with complicated than in those with uncomplicated PAA. Nevertheless, the diagnostic performance of CK was only moderate in the two settings analyzed. The potential usefulness of CK determination as a tool to guide the preoperative rehydration regimen of patients with PAA to prevent postoperative hyporexia and vomiting is a promising line of research and should be evaluated in future studies.
Source: Pediatric Surgery International - December 10, 2022 Category: Surgery Source Type: research

Postinduction Dexamethasone and Individualized Dosing of Escherichia Coli L-Asparaginase Each Improve Outcome of Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia: Results From a Randomized Study--Dana-Farber Cancer Institute ALL Consortium Protocol 00-01 Pediatric Oncology
Conclusion There was no overall difference in skeletal toxicity by corticosteroid type; dexamethasone was associated with more infections and, in older children, increased incidence of osteonecrosis and fracture. There was no difference in asparaginase-related toxicity by EC-Asnase dosing method. Dexamethasone and ID EC-Asnase were each associated with superior EFS. Monitoring NSAA during treatment with EC-Asnase may be an effective strategy to improve outcome in pediatric ALL.
Source: Journal of Clinical Oncology - March 15, 2013 Category: Cancer & Oncology Authors: Vrooman, Stevenson, Supko, O'Brien, Dahlberg, Asselin, Athale, Clavell, Kelly, Kutok, Laverdiere, Lipshultz, Michon, Schorin, Relling, Cohen, Neuberg, Sallan, Silverman Tags: Acute Lymphoblastic Leukemia Pediatric Oncology Source Type: research

Antibiotic Resistance Patterns of Outpatient Pediatric Urinary Tract Infections
We examined outpatient urinary isolates from patients younger than 18 years in 2009 using The Surveillance Network®, a database with antibiotic susceptibility results and patient demographic data from 195 United States hospitals. We determined the prevalence and antibiotic resistance patterns for the 6 most common uropathogens, ie Escherichia coli, Proteus mirabilis, Klebsiella, Enterobacter, Pseudomonas aeruginosa and Enterococcus. We compared differences in uropathogen prevalence between males and females using chi-square analysis. Results: We identified 25,418 outpatient urinary isolates. E. coli was the most common ...
Source: The Journal of Urology - January 29, 2013 Category: Urology & Nephrology Authors: Rachel S. Edlin, Daniel J. Shapiro, Adam L. Hersh, Hillary L. Copp Tags: Pediatric Urology Source Type: research

Value of Point‐of‐care Ketones in Assessing Dehydration and Acidosis in Children With GastroenteritisLa Importancia de Determinar los Cuerpos Cetónicos en el Momento de la Atención para Valorar la Deshidratación y la Acidosis en los Niños con Gastroenteritis
ConclusionsChildren with gastroenteritis and dehydration have elevated serum ketone concentrations that correlate with both degree of dehydration and magnitude of metabolic acidosis. Point‐of‐care serum ketone measurement may be a useful tool to inform management decisions at the point of triage or in the initial evaluation of children with gastroenteritis and dehydration. Resumen ObjetivosLos niños con gastroenteritis a menudo desarrollan deshidratación y acidosis metabólica. Los cuerpos cetónicos séricos están frecuentemente elevados en esta población. El objetivo fue determinar la relación entre la concentr...
Source: Academic Emergency Medicine - November 15, 2013 Category: Emergency Medicine Authors: Jason A. Levy, Mark Waltzman, Michael C. Monuteaux, Richard G. Bachur Tags: Original Research Contribution Source Type: research

Value of Point‐of‐care Ketones in Assessing Dehydration and Acidosis in Children With Gastroenteritis / La Importancia de Determinar los Cuerpos Cetónicos en el Momento de la Atención para Valorar la Deshidratación y la Acidosis en los Niños con Gastroenteritis
ConclusionsChildren with gastroenteritis and dehydration have elevated serum ketone concentrations that correlate with both degree of dehydration and magnitude of metabolic acidosis. Point‐of‐care serum ketone measurement may be a useful tool to inform management decisions at the point of triage or in the initial evaluation of children with gastroenteritis and dehydration. Resumen ObjetivosLos niños con gastroenteritis a menudo desarrollan deshidratación y acidosis metabólica. Los cuerpos cetónicos séricos están frecuentemente elevados en esta población. El objetivo fue determinar la relación entre la concentr...
Source: Academic Emergency Medicine - November 15, 2013 Category: Emergency Medicine Authors: Jason A. Levy, Mark Waltzman, Michael C. Monuteaux, Richard G. Bachur Tags: Original Research Contribution Source Type: research

Variation in Antibiotic Susceptibility of Uropathogens by Age Among Ambulatory Pediatric Patients
We compared uropathogen antibiotic susceptibility across age groups of ambulatory pediatric patients. For Escherichia coli (n=5,099) and other Gram-negative rods (n=626), significant differences (p
Source: Journal of Pediatric Nursing - October 2, 2013 Category: Nursing Authors: Jessina C. McGregor, Yennie Quach, David T. Bearden, David H. Smith, Susan E. Sharp, Judith A. Guzman-Cottrill Tags: Articles Source Type: research

A prospective study on drug monitoring of PEGasparaginase and Erwinia asparaginase and asparaginase antibodies in pediatric acute lymphoblastic leukemia
This study prospectively analyzed the efficacy of very prolonged courses of pegylated Escherichia coli asparaginase (PEGasparaginase) and Erwinia asparaginase in pediatric acute lymphoblastic leukemia (ALL) patients. Patients received 15 PEGasparaginase infusions (2500 IU/m2 every 2 weeks) in intensification after receiving native E coli asparaginase in induction. In case of allergy to or silent inactivation of PEGasparaginase, Erwinia asparaginase (20 000 IU/m2 2-3 times weekly) was given. Eighty-nine patients were enrolled in the PEGasparaginase study. Twenty (22%) of the PEGasparaginase–treated patients developed ...
Source: Blood - March 27, 2014 Category: Hematology Authors: Tong, W. H., Pieters, R., Kaspers, G. J. L., te Loo, D. M. W. M., Bierings, M. B., van den Bos, C., Kollen, W. J. W., Hop, W. C. J., Lanvers-Kaminsky, C., Relling, M. V., Tissing, W. J. E., van der Sluis, I. M. Tags: Pediatric Hematology, Free Research Articles, Lymphoid Neoplasia, Clinical Trials and Observations Source Type: research

Importance of blood cultures from peripheral veins in pediatric patients with cancer and a central venous line
ConclusionsBlood cultures should be obtained from a PV in addition to cultures from CVL at the onset of fever in pediatric patients with cancer in order to maximize the findings of true BSIs. The frequency of CRBSI may be over‐estimated if blood cultures are drawn from CVL only. Pediatr Blood Cancer © 2014 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - September 11, 2014 Category: Cancer & Oncology Authors: Mette Møller Handrup, Jens Kjølseth Møller, Cecilie Rutkjær, Henrik Schrøder Tags: Research Article Source Type: research

Detection and Molecular Characterization of Giardia duodenalis in Children Attending Day Care Centers in Majadahonda, Madrid, Central Spain
Abstract: Infections by the protozoan enteroparasites Giardia duodenalis and Cryptosporidium spp are a major cause of morbidity in children attending day care facilities in developed countries. In this cross-sectional study, we aimed to estimate the occurrence and genotype frequencies of these pathogens in children attending day care centers in Majadahonda, Central Spain. To do so, single stool samples were obtained from 90 children and tested for the presence of G duodenalis and Cryptosporidium spp by conventional microscopy and immunochromatography. Positive results by these techniques were subsequently confirmed by immu...
Source: Medicine - September 1, 2014 Category: Internal Medicine Tags: Article Source Type: research

Emergence of Escherichia coli Sequence Type 131 (ST131) and ST3948 with KPC-2, KPC-3 and KPC-8 carbapenemases from a Long-Term Care and Rehabilitation Facility (LTCRF) in Northern Italy.
Authors: Piazza A, Caltagirone M, Bitar I, Nucleo E, Spalla M, Fogato E, D'Angelo R, Pagani L, Migliavacca R Abstract Aim of the study was to characterize KPC-producing Escherichia coli (KPC-Ec) clinical isolates among a Northern Italy Long-Term Care and Rehabilitation Facility (LTCRF) residents. Thirteen consecutive non repeated MDR E. coli isolates showing ertapenem Minimum Inhibitory Concentrations (MICs) >0.5 mg/L, collected during the period March 2011 - May 2013 from ASP "Redaelli" inpatients, were investigated. The bla KPC/CTX-M/SHV/TEM/OXA genes were identified by PCR and sequencing. KPC-Ec isolates und...
Source: Advances in Experimental Medicine and Biology - January 28, 2016 Category: Research Tags: Adv Exp Med Biol Source Type: research

Dust mite allergen Der f 4: Expression, characterization, and IgE‐binding in pediatric asthma
ConclusionsThis initial cloning and characterization of the Der f 4 allergen serves as a foundation for future studies into the clinical importance and application of this protein for house dust mite allergy.This article is protected by copyright. All rights reserved.
Source: Pediatric Allergy and Immunology - February 4, 2016 Category: Allergy & Immunology Authors: Yu‐bao Cui, Li‐li Yu, Fei‐xiang Teng, Nan Wang, Ying Zhou, Li Yang, Cheng‐bo Zhang Tags: Original Source Type: research

Repeated Blood Cultures in Pediatric Febrile Neutropenia: Would Following the Guidelines Alter the Outcome?
ConclusionsOf 294 FN episodes with an initial negative blood culture, only one episode of bacteremia occurred without hemodynamic changes past day 3, supporting the IDSA guidelines to discontinue blood cultures in stable FN patients after day 3.
Source: Pediatric Blood and Cancer - March 10, 2016 Category: Cancer & Oncology Authors: Lindsay A. Petty, Elizabeth A. Sokol, Allison H. Bartlett, Jennifer L. McNeer, Kenneth A. Alexander, Jennifer Pisano Tags: Research Article Source Type: research

Dust mite allergen Der f 4: Expression, characterization, and IgE binding in pediatric asthma
ConclusionsThis initial cloning and characterization of the Der f 4 allergen serves as a foundation for future studies into the clinical importance and application of this protein for house dust mite allergy.
Source: Pediatric Allergy and Immunology - May 26, 2016 Category: Allergy & Immunology Authors: Yu‐bao Cui, Li‐li Yu, Fei‐xiang Teng, Nan Wang, Ying Zhou, Li Yang, Cheng‐bo Zhang Tags: Original Article Source Type: research

Increased EHEC survival and virulence gene expression indicate an enhanced pathogenicity upon simulated pediatric gastrointestinal conditions.
CONCLUSION: Differences in digestive physicochemical parameters may partially explain why children are more susceptible to EHEC infection than adults. Such data are essential for a full understanding of EHEC pathogenesis and would help in designing novel therapeutic approaches. PMID: 27429202 [PubMed - in process]
Source: Pediatric Research - October 31, 2016 Category: Pediatrics Authors: Roussel C, Cordonnier C, Galia W, Le Goff O, Thévenot J, Chalancon S, Alric M, Thevenot-Sergentet D, Leriche F, Van de Wiele T, Livrelli V, Blanquet-Diot S Tags: Pediatr Res Source Type: research