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Infectious Disease: Gastroenteritis
Nutrition: Flavonoids
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Total 906 results found since Jan 2013.
Regioselective O-acetylation of various glucosides catalyzed by Escherichia coli maltose O-acetyltransferase
Appl Microbiol Biotechnol. 2023 Sep 20. doi: 10.1007/s00253-023-12790-z. Online ahead of print.ABSTRACTEscherichia coli, a well-known prokaryotic organism, has been widely employed as a versatile host for heterologous overexpression of proteins/biocatalysts and the production of pharmaceutically important intermediates/small molecules. However, some E. coli endogenous enzymes showing substrate promiscuity may disturb the heterologous metabolic flux, which will result in the reduction of substrates, intermediates, and target products. Here we reported an unexpected E. coli-catalyzed regioselective O-acetylation of various g...
Source: Applied Microbiology and Biotechnology - September 20, 2023 Category: Microbiology Authors: Yi Li Xuefei Wang Zhan Liu Yun Yang Liangzhen Jiang Xixing Qu Xiang Pu Yinggang Luo Source Type: research
Alterations of fecal microbiome and metabolome in pemphigus patients
J Autoimmun. 2023 Sep 13:103108. doi: 10.1016/j.jaut.2023.103108. Online ahead of print.ABSTRACTThe role of gut microbiome and metabolic substances in the development of autoimmune diseases has gradually been revealed. However, the relevant gut features in pemphigus have not been well clarified. We collected stool samples from pemphigus patients and healthy controls (HCs). Metagenomic sequencing and liquid chromatography-mass spectrometry (LC/MS) metabolome sequencing were performed to analyze the compositional and metabolic alternations of the gut microbiome in pemphigus patients and HCs. We observed the reduced richness ...
Source: Journal of Autoimmunity - September 15, 2023 Category: Allergy & Immunology Authors: Ziyu Guo Nam Yiu Zhi Hu Wenyu Zhou Xuan Long Miao Yang Jieyue Liao Guiying Zhang Qianjin Lu Ming Zhao Source Type: research
Encapsulation of Dicranopteris linearis extract using cellulose microparticles for antiulcer medication
Int J Biol Macromol. 2023 Sep 7:126795. doi: 10.1016/j.ijbiomac.2023.126795. Online ahead of print.ABSTRACTDicranopteris linearis (DL) is a fern in the Gleicheniaceae family, locally known as resam by the Malay community. It has numerous pharmacological benefits, with antiulcer and gastroprotective properties. Peptic ulcer is a chronic and recurring disease that significantly impacts morbidity and mortality, affecting nearly 20 % of the world's population. Despite the effectiveness of peptic ulcer drugs, there is no perfect treatment for the ailment. Encapsulation is an advanced technique that can treat peptic ulcers by in...
Source: International Journal of Biological Macromolecules - September 9, 2023 Category: Biochemistry Authors: Anis Adilah Ahmad Khairul Farihan Kasim Subash C B Gopinath Periasamy Anbu Noor Soffalina Sofian Seng Source Type: research
Phytochemical investigation of Pistacia lentiscus L. var. Chia leaves: A byproduct with antimicrobial potential
Fitoterapia. 2023 Aug 8:105648. doi: 10.1016/j.fitote.2023.105648. Online ahead of print.ABSTRACTPistacia lentiscus L. var. Chia belongs to the Anacardiaceae family, and it is cultivated only in the south part of Chios island, in Greece. Even though it is renowned for its unique resin, Chios mastic gum (CMG), the tree leaves have also been used in traditional medicine, while the annual pruning generates a large biomass of unused by-products. Thus, the aim of the present study was the detailed phytochemical investigation of P. lentiscus var. Chia leaves towards the search of antimicrobial agents. UPLC-HRMS & HRMS/MS bas...
Source: Fitoterapia - August 10, 2023 Category: Biochemistry Authors: Christodoulos Anagnostou Stavros Beteinakis Anastasia Papachristodoulou Vasiliki K Pachi Mariangela Dionysopoulou Sofia Dimou George Diallinas Leandros A Skaltsounis Maria Halabalaki Source Type: research
Phytochemical Profiling and Pharmacological Evaluation of Leaf Extracts of Ruellia tuberosa L: An In Vitro and In Silico Approach
Chem Biodivers. 2023 Aug 4:e202300495. doi: 10.1002/cbdv.202300495. Online ahead of print.ABSTRACTThe present study was designed to appraise the photoprotective, antioxidant, and antibacterial bioactivities of Ruellia tuberosa leaves extracts (RtPE, RtChl, RtEA, RtAc, RtMe, and RtHMe). The results showed that the RtHMe extract of leaves of R. tuberosa was rich in total phenolic content i.e., 1.60 mgGAE/g dry extract, while TFC highest total flavonoid content was found in RtAc extract, i.e., 0.40 mgQE/g. RtMe showed effective antioxidant activity (%RSA: 58.16) at the concentration of 120 µL. RtMe, RtEA and RtHMe exhibited ...
Source: Chemistry and Biodiversity - August 4, 2023 Category: Biochemistry Authors: Akanksha Sharma Adarsh Kumar Ankit Kumar Singh Harshwardhan Singh K Jayaram Kumar Pradeep Kumar Source Type: research
Antibacterial Activity of Eight Medicinal Plants from the Traditional Pharmacopoeia of Niger
J Trop Med. 2023 Jul 24;2023:6120255. doi: 10.1155/2023/6120255. eCollection 2023.ABSTRACTThe emergence of multidrug bacterial resistance poses a great public health problem and requires a constant search for new antibacterial agents. However, Niger's flora possesses several medicinal plants used in traditional medicine to cure infectious diseases and can be used as sources of bioactive ingredients. This current study was designed to evaluate the antibacterial activity of eight plants used in the traditional pharmacopeia of Niger. The extracts were prepared by maceration using ethanol, methanol, and distilled water. The ob...
Source: Journal of Tropical Medicine - August 2, 2023 Category: Tropical Medicine Authors: Mahamane Idi Issa Abdoulahi Melogmo Dongmo Yanick Kevin Tchokouaha Yamthe Lauve Rachel Hama Hamadou Habibou Bakasso Sahabi Alio Sanda Abdelkader Fabrice Fekam Boyom Ilagouma Amadou Tidjani Source Type: research
