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Infectious Disease: Pandemics
Vaccination: Pneomococcal Vaccine
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Total 548 results found since Jan 2013.
Patient-reported reactogenicity and safety of COVID-19 vaccinations vs. comparator vaccinations: a comparative observational cohort study
CONCLUSION: The rate of adverse reactions after established vaccinations was roughly comparable to previous studies. Two weeks after vaccination, participants in the SARS-CoV-2 vaccination group reported more local and systemic local reactions than participants in the comparator group. In the further course, however, there were no higher odds of medical consultations in either of the two groups. Thus, altogether, we assume comparable safety.TRIAL REGISTRATION: DRKS-ID DRKS00025881 and DRKS-ID DRKS00025373.PMID:37726711 | DOI:10.1186/s12916-023-03064-6
Source: Herpes - September 19, 2023 Category: Infectious Diseases Authors: Felix Werner Nikoletta Zeschick Thomas K ühlein Philipp Steininger Klaus Überla Isabelle Kaiser Maria Sebasti ão Susann Hueber Lisette Warkentin Source Type: research
COVID-19: An Overview of SARS-CoV-2 Variants-The Current Vaccines and Drug Development
Biomed Res Int. 2023 Aug 29;2023:1879554. doi: 10.1155/2023/1879554. eCollection 2023.ABSTRACTThe world is presently in crisis facing an outbreak of a health-threatening microorganism known as COVID-19, responsible for causing uncommon viral pneumonia in humans. The virus was first reported in Wuhan, China, in early December 2019, and it quickly became a global concern due to the pandemic. Challenges in this regard have been compounded by the emergence of several variants such as B.1.1.7, B.1.351, P1, and B.1.617, which show an increase in transmission power and resistance to therapies and vaccines. Ongoing researches are ...
Source: Biomed Res - September 7, 2023 Category: Research Authors: Narjess Bostanghadiri Pardis Ziaeefar Morvarid Golrokh Mofrad Parsa Yousefzadeh Ali Hashemi Davood Darban-Sarokhalil Source Type: research
COVID-19 patients hospitalized after the fourth wave of the pandemic period in Vietnam: Clinical, laboratory, therapeutic features, and clinical outcomes
CONCLUSIONS: Severe and critical COVID-19 patients frequently have several comorbidities, multiple lung lesions along with a variety of clinical signs. Despite receiving antivirals, antibiotics, corticosteroids, anticoagulants, and even ECMO therapy, the patient encountered multiple complications, with a fatality rate of up to 38.27%.PMID:37574340 | DOI:10.1016/j.jfma.2023.07.020
Source: J Formos Med Assoc - August 13, 2023 Category: General Medicine Authors: Trinh Cong Dien Le Van Nam Pham Ngoc Thach Le Van Duyet Source Type: research
SARS-CoV-2 variants, its recombinants and epigenomic exploitation of host defenses
Biochim Biophys Acta Mol Basis Dis. 2023 Aug 5:166836. doi: 10.1016/j.bbadis.2023.166836. Online ahead of print.ABSTRACTSince 2003, we have seen the emergence of novel viruses, such as SARS-CoV-1, MERS, ZIKA, swine flu virus H1N1, Marburg, Monkeypox, Ebola, and SARS-CoV-2, but none of them gained pandemic proportions similar to SARS-CoV-2. This could be attributed to unique viral traits, allowing its rapid global dissemination following its emergence in October 2019 in Wuhan, China, which appears to be primarily driven by the emergence of highly transmissible and virulent variants that also associate, in some cases, with s...
Source: Biochimica et Biophysica Acta - August 7, 2023 Category: Biochemistry Authors: Nitin K Saksena Srinivas Bonam Reddy Monica Miranda-Saksena Thyago H S Cardoso Edson M A Silva Juliana C Fereira Wael M Rabeh Source Type: research
Impact of methotrexate treatment on vaccines immunogenicity in adult rheumatological patients - Lessons learned from the COVID-19 pandemic
Biomed Pharmacother. 2023 Aug 3;165:115254. doi: 10.1016/j.biopha.2023.115254. Online ahead of print.ABSTRACTDespite the development of new biological and synthetic targeted therapies, methotrexate remains one of the most commonly used immunomodulatory drugs in rheumatology. However, its effect on the immunogenicity of vaccines has been studied only to a limited extent until recently, resulting in the lack of clear guidelines on the use of methotrexate during vaccination. Significant progress was made during the COVID-19 pandemic due to the dynamic development of research on vaccines, including patients with autoimmune inf...
Source: Herpes - August 5, 2023 Category: Infectious Diseases Authors: Jakub Wro ński Marzena Ciechomska Ewa Kuca-Warnawin Source Type: research
Immune responses to SARS-CoV-2 infection and vaccination in children
Semin Immunol. 2023 Jun 20;69:101794. doi: 10.1016/j.smim.2023.101794. Online ahead of print.ABSTRACTDuring the three years since SARS-CoV-2 infections were first described a wealth of information has been gathered about viral variants and their changing properties, the disease presentations they elicit and how the many vaccines developed in record time protect from COVID-19 severe disease in different populations. A general theme throughout the pandemic has been the observation that children and young people in general fare well, with mild symptoms during acute infection and full recovery thereafter. It has also become cl...
Source: Seminars in Immunology - August 3, 2023 Category: Allergy & Immunology Authors: Petter Brodin Source Type: research
Opportunities to accelerate immunization progress in middle-income countries
Vaccine. 2023 Jul 15:S0264-410X(23)00782-X. doi: 10.1016/j.vaccine.2023.06.079. Online ahead of print.ABSTRACTThere has been increasing recognition of vaccine access challenges in middle-income countries and the need for increased action, particularly in countries that are not eligible for or have transitioned out of Gavi, the Vaccine Alliance support. These countries' immunization systems are more vulnerable than ever as the COVID-19 pandemic exacerbates existing programme challenges, increasing the risk of delayed vaccine introductions, backsliding immunization coverage rates, and increased coverage inequity. The potenti...
Source: Vaccine - July 17, 2023 Category: Allergy & Immunology Authors: Jason Zhu Clarke B Cole Johanna Fihman Alex Adjagba Mira Dasic Tania Cernuschi Source Type: research
An in-depth appraisal of clinico-biochemical and radiological findings of COVID-19 patients during the COVID-19 pandemic in a dedicated COVID Care Hospital in Eastern India and its outcome in relation to the COVAXIN vaccination status: A 2-year study
CONCLUSION: Immune dysregulation plays a central role in the pathogenesis of the manifestations. Vaccine-induced protection and the induction of herd immunity played a proactive role in the waning of the severity of clinical presentations.PMID:37448914 | PMC:PMC10336931 | DOI:10.4103/jfmpc.jfmpc_1853_22
Source: Primary Care - July 14, 2023 Category: Primary Care Authors: C Mohan Rao Amrut Kumar Mohapatra Aswini Kumar Patnaik Prem S Panda Prasanta Ranjan Behera Source Type: research
Distinct Features of Vascular Diseases in COVID-19
J Inflamm Res. 2023 Jul 6;16:2783-2800. doi: 10.2147/JIR.S417691. eCollection 2023.ABSTRACTThe Coronavirus Disease 2019 (COVID-19) pandemic was declared in early 2020 after several unexplained pneumonia cases were first reported in Wuhan, China, and subsequently in other parts of the world. Commonly, the disease comprises several clinical features, including high temperature, dry cough, shortness of breath, and hypoxia, associated with findings of interstitial pneumonia on chest X-ray and computer tomography. Nevertheless, severe forms of acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) are not limited to the ...
Source: Atherosclerosis - July 12, 2023 Category: Cardiology Authors: Alexandr Ceasovschih Victorita Sorodoc Annabelle Shor Raluca Ecaterina Haliga Lynn Roth Catalina Lionte Viviana Onofrei Aursulesei Oana Sirbu Nicolae Culis Albina Shapieva Mohammed A R Tahir Khokhar Cristian Statescu Radu A Sascau Adorata Elena Coman Alex Source Type: research
