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Characteristics and Outcomes of Patients With Multiple Cervical Artery Dissection Clinical Sciences
Conclusions— In the largest published series of patients with CeAD, we highlighted significant differences between multiple and single artery involvement. Features suggestive of an underlying vasculopathy (fibromuscular dysplasia) and environmental triggers (recent infection, cervical manipulation, and a remote history of head or neck surgery) were preferentially associated with multiple CeAD.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Bejot, Y., Aboa-Eboule, C., Debette, S., Pezzini, A., Tatlisumak, T., Engelter, S., Grond-Ginsbach, C., Touze, E., Sessa, M., Metso, T., Metso, A., Kloss, M., Caso, V., Dallongeville, J., Lyrer, P., Leys, D., Giroud, M., Pandolfo, M., Abboud, S., on behal Tags: Carotid and Vertebral A. Dissection Clinical Sciences Source Type: research

Connective tissue anomalies in patients with spontaneous cervical artery dissection
Conclusions: Connective tissue abnormalities are frequent in patients with sCeAD. This reinforces the hypothesis that systemic aberrations of the connective tissue might be implicated in the pathogenesis of the disease.
Source: Neurology - November 24, 2014 Category: Neurology Authors: Giossi, A., Ritelli, M., Costa, P., Morotti, A., Poli, L., Del Zotto, E., Volonghi, I., Chiarelli, N., Gamba, M., Bovi, P., Tomelleri, G., Carletti, M., Checcarelli, N., Meneghetti, G., Morra, M., Chinaglia, M., De Giuli, V., Colombi, M., Padovani, A., Pe Tags: Stroke in young adults, Carotid artery dissection, Risk factors in epidemiology ARTICLE Source Type: research

Spontaneous Bilateral Cervical Internal Carotid and Vertebral Artery Dissection in a Japanese Patient without Collagen Vascular Disease with Special Reference to Single-Nucleotide Polymorphisms
Spontaneous cervical artery dissection (sCAD) is a major cause of ischemic stroke in young adults. Frequently, sCAD involves multiple neck arteries, accounting for 13%-28% of the total sCAD cases. However, little is known about factors related to multiple sCAD. In this case, a 52-year-old man was admitted due to headache without aura. There was a personal history of migraine with aura and a family history of similar symptoms. The patient's younger brother had a left vertebral artery (VA) dissecting aneurysm and underwent endovascular occlusion of his parent artery at the age of 48.
Source: Journal of Stroke and Cerebrovascular Diseases - May 19, 2016 Category: Neurology Authors: Arata Abe, Chikako Nito, Yuki Sakamoto, Akane Nogami, Hiroyuki Hokama, Shiro Takahashi, Kumiko Kirita, Masayuki Ueda, Yoshiro Ishimaru, Kazumi Kimura Tags: Case Studies Source Type: research

Clinical Presentation, Magnetic Resonance Angiography, Ultrasound Findings, and Stroke Patterns in Patients with Vertebral Artery Dissection
Background/Aims: Vertebral artery dissection (VAD) is an important cause of ischemic stroke. In this observational study, clinical data, magnetic resonance (MR) and ultrasound (US) imaging findings and ischemic patterns were analyzed.Methods: Forty-seven patients with a diagnosis of VAD underwent clinical examination, US, MR of the brain and neck and MR angiography (MRA) of the cervical arteries. Vascular abnormalities and ischemic brain lesions were noted. Data were evaluated separately and compared for spontaneous and traumatic VAD subgroups.Results: The most common overall clinical symptom was vertigo followed by neck p...
Source: European Neurology - October 31, 2016 Category: Neurology Source Type: research

Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? Yes
ConclusionThere are several methodological challenges to understanding the association between neck manipulation and vertebral artery dissection. Addressing these issues is critical because even a modest association between neck manipulation and cervical artery dissection could translate into a significant number of avoidable dissections given the widespread use of neck manipulation by providers from various backgrounds. We believe that valid case classification, accurate measurement of manipulative procedures, and addressing reverse causation bias should be top priorities for future research.
Source: Chiropractic and Manual Therapies - November 4, 2016 Category: Complementary Medicine Source Type: research

Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? No
The purported relationship between cervical manipulative therapy (CMT) and stroke related to vertebral artery dissection (VAD) has been debated for several decades. A large number of publications, from case re...
Source: Chiropractic and Osteopathy - November 5, 2016 Category: Complementary Medicine Authors: Donald R. Murphy, Michael J. Schneider, Stephen M. Perle, Christopher G. Bise, Michael Timko and Mitchell Haas Source Type: research

Does case misclassification threaten the validity of studies investigating the relationship between neck manipulation and vertebral artery dissection stroke? Yes
For patients and health care providers who are considering spinal manipulative therapy of the neck, it is crucial to establish if it is a trigger for cervical artery dissection and/or stroke, and if it is, the...
Source: Chiropractic and Osteopathy - November 5, 2016 Category: Complementary Medicine Authors: Jessica K. Paulus and David E. Thaler Source Type: research

Antiplatelet Therapy vs Anticoagulation Therapy in Cervical Artery Dissection: The Cervical Artery Dissection in Stroke Study (CADISS) Randomized Clinical Trial Final Results.
A randomized, prospective study from the United Kingdom and Australia was conducted between February 24, 2006 and June 17, 2013.
Source: Journal of Vascular Surgery - November 22, 2019 Category: Surgery Authors: H.S. Markus, C. Levi, A. King, J. Madigan, J. Norris, Cervical Artery Dissection in Stroke Study (CADISS) Investigators. Tags: There is no difference in treatment of carotid or vertebral artery dissection with antiplatelet vs anticoagulant therapy Source Type: research

Angiographical Identification of Intracranial, Atherosclerosis-Related, Large Vessel Occlusion in Endovascular Treatment
Conclusions Among only a few identification methods, the ICAS-LVO can be feasibly identified by angiographical findings. The identification of ICAS-LVO based on based on occlusion type, is a reliable and practical identification method for ICAS-LVO. Procedural details by occlusion type and its predictability to endovascular results were reported. Furthermore, occlusion type can be determined before or in the early stages of the procedure, which may be most helpful in setting up an optimal endovascular treatment strategy. Author Contributions J-HB established the study idea, designed the manuscript structure, acquired an...
Source: Frontiers in Neurology - April 15, 2019 Category: Neurology Source Type: research

Antiplatelet treatment compared with anticoagulation treatment for cervical artery dissection (CADISS): a randomised trial
Publication date: Available online 12 February 2015 Source:The Lancet Neurology Background Extracranial carotid and vertebral artery dissection is an important cause of stroke, especially in young people. In some observational studies it has been associated with a high risk of recurrent stroke. Both antiplatelet drugs and anticoagulant drugs are used to reduce risk of stroke but whether one treatment strategy is more effective than the other is unknown. We compared their efficacy in the Cervical Artery Dissection in Stroke Study (CADISS), with the additional aim of establishing the true risk of recurrent stroke. Methods W...
Source: The Lancet Neurology - February 13, 2015 Category: Neurology Source Type: research

A single-center experience of 30-day perioperative and one year clinical outcomes of transcarotid artery revascularization in 100 consecutive patients
CONCLUSION: Although the perioperative events were somewhat higher than what has been reported in previous registries, TCAR for patients who are high-risk for CEA has a low perioperative stroke and stroke/death rates with satisfactory outcome at 1 year. Further long-term data is probably needed to verify long-term outcome.PMID:35634873 | DOI:10.1177/17085381221106330
Source: Vascular - May 31, 2022 Category: Surgery Authors: Ali F AbuRahma Zachary T AbuRahma Adrian Santini Matthew Beasley Meghan Davis Andrew Lee Christina Veith Mazen Roshdy L Scott Dean Elaine Davis Source Type: research

Differences and Similarities Between Spontaneous Dissections of the Internal Carotid Artery and the Vertebral Artery
There are clinical, pathologic, and outcome differences in spontaneous dissections of the internal carotid artery vs those of the vertebral artery. Spontaneous cervical artery dissection is a major cause of stroke in younger patients. Spontaneous cervical artery dissection causes up to 25% of all ischemic strokes in patients 15 to 49 years of age (Putaala J et al, Stroke 2009;40:1195-203). Although constitutional and environmental factors are both thought to play a role in spontaneous cervical artery dissection, precise causes are poorly understood. Significant differences between spontaneous internal carotid artery disse...
Source: Journal of Vascular Surgery - December 27, 2013 Category: Surgery Authors: M. von Babo, G.M. De Marchis, H. Sarikaya Tags: Abstracts Source Type: research

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