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Total 139 results found since Jan 2013.

Exogenous Neural Stem Cells Transplantation as a Potential Therapy for Photothrombotic Ischemia Stroke in Kunming Mice Model
In this study, we explore the transplantation of exogenous neural stem cells (NSCs) as the potential therapy for the photothrombotic ischemia stroke in a Kunming mice model. After stroke, mice receiving NSC transplantation demonstrated a better recovery of brain function during the neurobehavioral tests. Histology analysis of the brain samples from NSC transplanted mice demonstrated a reduction of brain damage caused by stroke. Moreover, immunofluorescence assay for biomarkers in brain sections confirmed that transplanted NSCs indeed differentiated to neurons and astrocytes, consistent with the improved brain function afte...
Source: Molecular Neurobiology - January 28, 2016 Category: Neurology Source Type: research

Early Palliative Care Consultation Decreases Length of Stay in Severe Stroke Patients (P1.211)
Conclusions:Early PCC in severe stroke patients decreased hospital LOS by 3 days. This may be due to prompt clarification of goals of care and hastened discharge to hospice. Advanced age, poor pre-stroke functional status, and severe post-stroke deficits and disability warrant early PCC. In addition to decreasing LOS, further study is needed to determine whether early PCC also limits futile tests, procedures, and iatrogenic complications. Ultimately, timely identification of PCC candidates may produce higher satisfaction and decreased hospital costs.Disclosure: Dr. Schloss has nothing to disclose. Dr. Tversky has nothing t...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Schloss, E. R., Tversky, S., Katz, J. M., Wright, P. Tags: Pain and Palliative Care Source Type: research

Involvement of Specialist Palliative Care in a Stroke Unit in Austria —Challenges for Families and Stroke Teams
Conclusions: Family members benefit from understandable and consistent information, emotional support, and a professional team identifying their needs. Stroke unit professionals need skills as well as knowledge and strategies in order to make decisions and provide treatment at the end-of-life, when there may be ethical or legal issues. Close cooperation with specialist palliative care services supports both treatment teams and families with communication and decision-making for patients with severe ischemic stroke.
Source: Frontiers in Neurology - September 22, 2021 Category: Neurology Source Type: research

The study protocol of: 'initiating end of life care in stroke: clinical decision-making around prognosis'
This study aims to investigate clinicians' use of different types of evidence in decisions to initiate end of life care within trajectories typical of the acute stroke population. Methods: This two-phase, mixed methods study comprises investigation of dying trajectories in acute stroke (Phase 1), and the use of clinical scenarios to investigate clinical decision-making in the initiation of palliative care (Phase 2). It will be conducted in four acute stroke services in North Wales and North West England. Patient and public involvement is integral to this research, with service users involved at each stage.DiscussionThis st...
Source: BMC Palliative Care - December 5, 2014 Category: Palliative Care Authors: Christopher BurtonSheila PayneMary TurnerTracey BucknallJo MalonePippa TyrrellMaria HorneLupetu NtambweSarah TysonHelen MitchellSion WilliamsSalah Elghenzai Source Type: research

The study protocol of: `Initiating end of life care in stroke: clinical decision-making around prognosis¿
This study aims to investigate clinicians’ use of different types of evidence in decisions to initiate end of life care within trajectories typical of the acute stroke population.Methods/designThis two-phase, mixed methods study comprises investigation of dying trajectories in acute stroke (Phase 1), and the use of clinical scenarios to investigate clinical decision-making in the initiation of palliative care (Phase 2). It will be conducted in four acute stroke services in North Wales and North West England. Patient and public involvement is integral to this research, with service users involved at each stage.DiscussionT...
Source: BMC Palliative Care - December 5, 2014 Category: Palliative Care Authors: Christopher BurtonSheila PayneMary TurnerTracey BucknallJo Rycroft-MalonePippa TyrrellMaria HorneLupetu NtambweSarah TysonHelen MitchellSion WilliamsSalah Elghenzai Source Type: research

Reflection on Stroke Deaths and end ‐of‐life stroke care
ConclusionIn this cohort, palliative care referral and EOLCP were commenced in less than 50% of patients, highlighting significant variations in clinical care. These data support the need to promote awareness of ACP, particularly in patients with prior stroke or significant co‐morbidities. This may help reduce potentially futile invasive investigations and treatment.
Source: Internal Medicine Journal - September 11, 2017 Category: Internal Medicine Authors: Syed Zujajuddin Quadri, Thang Huynh, Cecilia Cappelen ‐Smith, Nirupama Wijesuriya, Abul Mamun, Roy Beran, Alan Mcdougall, Dennis Cordato Tags: Original Article Source Type: research

Outcomes, experiences and palliative care in major stroke: a multicentre, mixed-method, longitudinal study.
Authors: Kendall M, Cowey E, Mead G, Barber M, McAlpine C, Stott DJ, Boyd K, Murray SA Abstract BACKGROUND: Case fatality after total anterior circulation stroke is high. Our objective was to describe the experiences and needs of patients and caregivers, and to explore whether, and how, palliative care should be integrated into stroke care. METHODS: From 3 stroke services in Scotland, we recruited a purposive sample of people with total anterior circulation stroke, and conducted serial, qualitative interviews with them and their informal and professional caregivers at 6 weeks, 6 months and 1 year. Interviews we...
Source: Canadian Medical Association Journal - March 7, 2018 Category: General Medicine Tags: CMAJ Source Type: research

The experience of uncertainty for patients, families and healthcare providers in post-stroke palliative and end-of-life care: a qualitative meta-synthesis
Conclusionsto mitigate the degree of uncertainty post-stroke, HCPs should be present, provide clear direct communication and incorporate the value-based goals of care within their medical treatment plan. These findings suggest that future research is needed to focus on how PC approaches can be integrated into stroke care programmes.
Source: Age and Ageing - November 18, 2020 Category: Geriatrics Source Type: research

Adverse consequences of immediate thrombolysis-related complications: a multi-centre registry-based cohort study of acute stroke
In conclusion, the risk of nosocomial infections, worsening of stroke severity, longer HASU stay, disability and death is increased following immediate TRC. The management of patients following immediate TRC is more complex than previously thought and such complexity needs to be considere d when planning an increased thrombolysis service.
Source: Journal of Thrombosis and Thrombolysis - July 13, 2021 Category: Hematology Source Type: research

Causes of Death in Endovascularly Treated Patients with Acute Stroke INTERVENTIONAL
CONCLUSIONS: Cerebrovascular causes in patients with stroke play a major role in the intrahospital causes of death and reasons for palliation. Considering the large proportion of secondarily palliative–treated patients, reasons for palliation should be considered instead of causes of death to avoid concealment by, for example, life-terminating measures.
Source: American Journal of Neuroradiology - September 7, 2022 Category: Radiology Authors: Nagel, H., Pinho, J., Hasan, D., Ridwan, H., Habib, P., Schulz, J. B., Wiesmann, M., Reich, A., Nikoubashman, O. Tags: INTERVENTIONAL Source Type: research

Communication, the key in creating dignified encounters in unexpected sudden death & #8211; With stroke as example
Conclusion: Communication shown as the foundation for dignified encounters in care as experienced by stroke team members and next of kin enables the patient to come forth as a unique person and uphold absolute dignity in care. Acknowledging the next of kin's familiarity with the severely ill patient will contribute to personalizing the patient and in this way be the ground for a person centeredness in care despite the patients' inability to defend their own interests. Through knowledge about the patient as a person, the foundation for dignified care is given, expressed through respect for the patient&...
Source: Indian Journal of Palliative Care - January 31, 2019 Category: Palliative Care Authors: Å sa CU Rejn ö Linda K Berg Source Type: research

The lived experience of patients suffering from stroke and their perception of palliative care needs: a literature review
This study aims to review the lived experience of patients suffering from stroke and describe their perception of palliative care needs. A literature review search was conducted. Web of Sciences, SAGE, CINAHL, PubMed and Jordanian Database for Nursing Research databases were used to search the literature. The findings of 37 articles were address palliative care approaches for patients with stroke, lived experiences of patients suffering from stroke and the experience, barriers and facilitators related to health-care service for stroke survivors. This review indicated the importance of recognizing palliative care n...
Source: Working with Older People - December 16, 2021 Category: Geriatrics Authors: Marwa Halabi Inaam Khalaf Salam Bani Hani Source Type: research

Dysphagia as a predictor of outcome and transition to palliative care among middle cerebral artery ischemic stroke patients
This study determined some predictors of early transition to palliative level of care among patients with acute ischemic MCA stroke with dysphagia. Methods: This is a retrospective cohort study. Demographic and clinical data of patients presenting to Hartford Hospital with an acute ischemic stroke between January 2005-December 2010 were gathered utilizing the Stroke Center at Hartford Hospital Database. The 236 patients included were divided into "early transition" and "not transitioned" to palliative care cohorts. Primary outcome was transition to palliative care. Factors that were significantly associated with an early t...
Source: BMC Palliative Care - Latest articles - May 10, 2013 Category: Palliative Care Authors: Christa San LuisIlene StaffGilbert FortunatoLouise McCullough Source Type: research

Survival, Functional Status, and Eating Ability After Percutaneous Endoscopic Gastrostomy Tube Placement for Acute Stroke
ConclusionIn this community‐based sample, individuals who had had a stroke and a PEG tube placed had high mortality, and survivors were unlikely to be functional or mobile or to recover eating ability after hospitalization. A palliative care discussion including goals of care should occur before PEG tube placement is considered.
Source: Journal of the American Geriatrics Society - April 27, 2017 Category: Geriatrics Authors: Karl Meisel, Robert M. Arnold, Irena Stijacic Cenzer, John Boscardin, Alexander K. Smith Tags: Brief Report Source Type: research

Validation of the caregiving knowledge questionnaire-my: Measuring knowledge regarding positioning and feeding among Malaysian informal caregivers of stroke patients
Conclusions: CKQ-My has good internal consistency and construct validity for the subscales measuring stroke caregivers' knowledge about positioning and feeding of stroke patients. It has potential as an assessment of effectiveness of caregiver training and for future studies on long-term stroke outcomes in Malaysia.
Source: Indian Journal of Palliative Care - October 15, 2018 Category: Palliative Care Authors: Chai-Eng Tan Aznida F Abdul Aziz May-Yin Hi Nur Sarah A Azmi Nur Khairina Ishak Fathin Alyaa Mohamad Farid Mohammad Nazri Zulkafli Source Type: research