Filtered By:
Specialty: Drugs & Pharmacology
Education: Study
This page shows you your search results in order of relevance. This is page number 10.
Order by Relevance | Date
Total 3586 results found since Jan 2013.
Clinical Effects of Dual Antiplatelet Therapy or Aspirin Monotherapy after Acute Minor Ischemic Stroke or Transient Ischemic Attack, a Meta-Analysis
CONCLUSIONS: Among patients with acute minor ischemic stroke or TIA, DAPT, as compared with aspirin monotherapy, might offer better effectiveness in terms of ischemic stroke recurrence at the expense of a higher risk of major bleeding. The trade-off between ischemic benefits and bleeding risks should be assessed in tailoring the therapeutic strategies.PMID:34323179 | DOI:10.2174/1381612827666210728102459
Source: Current Pharmaceutical Design - July 29, 2021 Category: Drugs & Pharmacology Authors: Francesco Condello Gaetano Liccardo Giuseppe Ferrante Source Type: research
Stroke patients ’ support: evaluation of knowledge, practices and training needs of French community pharmacists
Conclusion Based on this small study, the fragmented knowledge and varied practices promote the need for further training for pharmacists to optimize support of stroke patients. This study promotes the elaboration of training systems adapted to pharmacists ’ needs. This will help support the development of a targeted pharmaceutical care approach for stroke patients.
Source: International Journal of Clinical Pharmacy - August 1, 2021 Category: Drugs & Pharmacology Source Type: research
Inflammatory Cytokines and Risk of Ischemic Stroke: A Mendelian Randomization Study
Conclusions: Our study suggested that genetically increased IL-4 levels showed a protective effect on the risk of ischemic stroke, which provides important new insights into the potential therapeutic target for preventing ischemic stroke.
Source: Frontiers in Pharmacology - January 17, 2022 Category: Drugs & Pharmacology Source Type: research
Pharmacists Act on Care Transitions in Stroke (PACT-Stroke): A Systems Approach
This study was a single-center, retrospective assessment of patients contacted by a pharmacist. All data were analyzed descriptively. Our initial evaluation of the Pharmacists Act on Care Transitions in Stroke (PACT-Stroke) service was to quantify and categorize drug-related problems (DRPs), which included drug selection, drug form, dose selection, treatment duration, dispensing, drug use process, patient-related problems, and other. Patients were included if they were adults who experienced an ischemic stroke. Exclusion criteria for this service included pediatric patients, patients with hemorrhagic strokes, patients with...
Source: Clinical Therapeutics - February 16, 2022 Category: Drugs & Pharmacology Authors: Jenna L Harris Danielle DelVecchio Robert W Seabury Christopher D Miller Elizabeth Phillips Source Type: research
Humanized cerebral organoids-based ischemic stroke model for discovering of potential anti-stroke agents
In this study we compared the cell composition of COs at different culture time and explored the cell types, cell ratios and volume size of COs at 85 days (85 d-CO). The 85 d-CO with diameter more than 2 mm was chosen for establishing humanized ischemic stroke model of OGD. By determining the time-injury relationship of the model, we observed aggravated ischemic injury of COs with OGD exposure time, obtaining first-hand evidence for the damage degree of COs under different OGD condition. The sensitivity of the model to ischemic injury and related treatment was validated by the proven pan-Caspase inhibitor Z-VAD-FMK (20 μM...
Source: Acta Pharmacologica Sinica - September 13, 2022 Category: Drugs & Pharmacology Authors: Shu-Na Wang Zhi Wang Xi-Yuan Wang Xiu-Ping Zhang Tian-Ying Xu Chao-Yu Miao Source Type: research
Neuropharmacological efficacy of metformin for stroke in rodents: A meta-analysis of preclinical trials
Conclusion: Overall, metformin treatment improves severe outcomes triggered by stroke. Despite the limitations intrinsic to animal studies, this systematic review may provide a vital reference for future high-quality preclinical trials and clinical use.
Source: Frontiers in Pharmacology - November 3, 2022 Category: Drugs & Pharmacology Source Type: research
Correlation between Vitamin D, homocysteine and brain-derived neurotrophic factor levels in patients with ischemic stroke
CONCLUSIONS: Vitamin D supplementation was used as a therapeutic agent in patients with acute ischemic stroke that affects homocysteine and BDNF levels. In this study, it was demonstrated for the first time that there is a correlation between serum vitamin D levels and BDNF levels in patients who have experienced a stroke.PMID:36394751 | DOI:10.26355/eurrev_202211_30154
Source: European Review for Medical and Pharmacological Sciences - November 17, 2022 Category: Drugs & Pharmacology Authors: U F Yurekli Z Tunc Source Type: research
