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Procedure: Carotid Endarterectomy

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Total 1996 results found since Jan 2013.

Contribution of Endoplasmic Reticulum Stress to the Clinical Instability of Carotid Plaques in Human Carotid Stenosis
AbstractEndoplasmic reticulum (ER) stress is an important process during the progression of atherosclerosis. The aim of this study was to elucidate the association of ER stress and clinical instability of carotid plaque. One hundred ninety-three patients with carotid stenosis undergoing carotid endarterectomies (CEAs) were enrolled. We classified the patients into 3 groups: the asymptomatic, symptomatic, and cTIA (crescendo transient ischemic attack)/SIE (stroke in evolution) groups. Immunohistological staining was performed to assess ER stress and apoptosis. The correlation between ER stress marker expression and clinical...
Source: Translational Stroke Research - November 16, 2021 Category: Neurology Source Type: research

Carotid Endarterectomy After Intracranial Endovascular Thrombectomy for Acute Ischaemic Stroke in Patients with Carotid Artery Stenosis
Recent randomised controlled trials demonstrated the benefit of intracranial endovascular thrombectomy (EVT) in acute ischaemic stroke. There is no consensus, however, on how to treat concomitant extracranial carotid artery stenosis after EVT. The aim of this study was to evaluate the outcome in patients treated with carotid endarterectomy (CEA) after EVT, comparing complication rates among patients undergoing CEA for stroke without previous EVT.
Source: European Journal of Vascular and Endovascular Surgery - December 6, 2021 Category: Surgery Authors: Magnus Jonsson, Ellinoora Aro, Katarina Bj örses, Staffan Holmin, Petra Ijäs, Nicolas Martinez-Majander, Pirkka Vikatmaa, Carl-Magnus Wahlgren, Maarit Venermo, Martin Björck Source Type: research

Effectiveness of an individualized home-based physical activity program in surgery-free non-endarterectomized asymptomatic stroke patients: a study protocol for the PACAPh interventional randomized trial
This study has been approved by the National Ethics Committee (IDRCB:2019-A01543-54/SI:19.06.21.40640). ClinicalTrials.gov NCT04053166.PMID:35164816 | DOI:10.1186/s13063-022-06061-x
Source: Atherosclerosis - February 15, 2022 Category: Cardiology Authors: Mathilde Mura Emeraude Rivoire Leila Dehina-Khenniche Mich èle Weiss-Gayet B énédicte Chazaud Camille Faes Philippe Connes Anne Long Chantal L Rytz Pauline Mury Lidia Delrieu Etienne Gouraud Marine Bordet Nellie Della Schiava Patrick Lermusiaux Matthie Source Type: research

National Institutes of Health stroke scale score at admission can predict functional outcomes in patients with ischemic stroke undergoing carotid endarterectomy
The aim of present study was to evaluate the prognostic effect of the National Institutes of Health stroke scale (NIHSS) score for patients who had undergone acute carotid endarterectomy (CEA) and assess the clinical and morphologic factors that could predict for worse outcomes.
Source: Journal of Vascular Surgery - December 23, 2021 Category: Surgery Authors: Davide Mastrorilli, Luca Mezzetto, Mario D'Oria, Roberta Fiorini, Sandro Lepidi, Lorenzo Scorsone, Edoardo Veraldi, Gian Franco Veraldi Source Type: research

Interleukin-6 Predicts Carotid Plaque Severity, Vulnerability, and Progression
CONCLUSIONS: Circulating IL-6 predicts carotid plaque severity, vulnerability, and progression. The 2.0 pg/mL cutoff could facilitate the selection of individuals that would benefit from anti-IL-6 drugs for stroke prevention.PMID:35713008 | DOI:10.1161/CIRCRESAHA.122.320877
Source: Circulation Research - June 17, 2022 Category: Cardiology Authors: Joseph Kamtchum-Tatuene Luca Saba Mirjam R Heldner Michiel H F Poorthuis Gert J de Borst Tatjana Rundek Stavros K Kakkos Seemant Chaturvedi Raffi Topakian Joseph F Polak Glen C Jickling Carotid Atherosclerosis and Stroke Collaboration (CASCO) Source Type: research

Ischemic Stroke in Patients With Asymptomatic Severe Carotid Stenosis Without Surgical Intervention
To the Editor In a recent study of the clinical outcomes of 3737 adults with asymptomatic severe carotid stenosis who did not undergo carotid revascularization, the 5-year ipsilateral stroke rate was 4.7%. The authors concluded that “these findings may inform decision-making regarding surgical and medical treatment for patients with asymptomatic severe carotid artery stenosis.” A multicenter randomized prospective trial from 2021 reported similar 5-year stroke rates for 3625 patients with asymptomatic severe carotid stenosi s who underwent carotid endarterectomy. Based on these studies, one could come to the conclusion...
Source: JAMA - September 27, 2022 Category: General Medicine Source Type: research

Stroke, Death, and MI After Transcarotid Artery Revascularization vs Carotid Endarterectomy
This cohort study compares risk of 30-day stroke, death, or myocardial infarction or 1-year ipsilateral stroke among patients with standard surgical risk undergoing transcarotid artery revascularization vs carotid endarterectomy.
Source: JAMA Neurology - March 20, 2023 Category: Neurology Source Type: research