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When does life end? New organ donation strategy fuels debate
On a chilly holiday Monday in January 2020, a medical milestone passed largely unnoticed. In a New York City operating room, surgeons gently removed the heart from a 43-year-old man who had died and shuttled it steps away to a patient in desperate need of a new one. More than 3500 people in the United States receive a new heart each year. But this case was different—the first of its kind in the country. “It took us 6 months to prepare,” says Nader Moazami, surgical head of heart transplantation at New York University (NYU) Langone Health, where the operation took place. The run-up included oversight from an ethi...
Source: ScienceNOW - May 11, 2023 Category: Science Source Type: news

Percheron Artery-Plus Syndrome: A Syndrome Beyond Stroke Chameleon
J Nippon Med Sch. 2021;88(4):375-379. doi: 10.1272/jnms.JNMS.2021_88-414.ABSTRACTThe artery of Percheron (AOP) is an anatomical variant of the thalamoperforating arteries. AOP occlusion can cause bilateral paramedian thalamic infarctions and is referred to as a "stroke chameleon" because it lacks the classic signs of stroke. Coexistence of AOP occlusion and other neurologic disease is rare and can cause disturbance of consciousness. A 78-year-old woman had acute onset of left limb weakness and drowsy consciousness. Brain magnetic resonance angiography (MRA) revealed acute bilateral paramedian thalamic infarctions. However,...
Source: Journal of Nippon Medical School - September 2, 2021 Category: Universities & Medical Training Authors: Fu-Yi Yang Jeng-Luen Hung Shinn-Kuang Lin Source Type: research

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Subarachnoid Hemorrhage due to Spinal Cord Schwannoma Presenting Findings Mimicking Meningitis
We report an unusual case of spinal SAH mimicking meningitis with normal brain computed tomography (CT)/magnetic resonance imaging (MRI) and negative CT angiography. Cerebrospinal fluid examination results were consistent with the manifestation of SAH. Spinal MRI performed subsequently showed an intradural extramedullary mass. The patient received surgery and was finally diagnosed with spinal cord schwannoma.
Source: Journal of Stroke and Cerebrovascular Diseases - May 23, 2016 Category: Neurology Authors: Hong-Mei Zhang, Yin-Xi Zhang, Qing Zhang, Shui-Jiang Song, Zhi-Rong Liu Tags: Case Studies Source Type: research

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis? Clinical Sciences
Conclusions— In children with dissection and transient cerebral arteriopathy, cerebral arteries demonstrate increased tortuosity. Quantified arterial tortuosity may represent a clinically relevant imaging biomarker of vascular biology in pediatric stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Wei, F., Diedrich, K. T., Fullerton, H. J., deVeber, G., Wintermark, M., Hodge, J., Kirton, A., the Vascular Effects of Infection in Pediatric Stroke (VIPS) Investigators, Dowling, Benedict, Bernard, Fox, Friedman, Lo, Ichord, Tan, Mackay, Hernandez, Hump Tags: Risk Factors, Angiography, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Vascular Disease Clinical Sciences Source Type: research

An Uncommon Cause for Multiple Cerebral Ischemic Infarcts (P4.344)
Conclusions: Cerebral infarcts due to CM in immunocompetent patients are unusual. However, cryptococcal infection should be considered in atypical stroke manifestations, since early diagnosis and prompt treatment can improve outcome.Disclosure: Dr. Khattak has nothing to disclose. Dr. Desai has nothing to disclose. Dr. Desai has nothing to disclose. Dr. Wise has nothing to disclose. Dr. Moore has nothing to disclose. Dr. Shah has nothing to disclose. Dr. Wilder has nothing to disclose. Dr. Remmel has nothing to disclose. Dr. Liu has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Khattak, J., Desai, M., Desai, D., Wise, E., Moore, K., Shah, J., Wilder, M., Remmel, K., Liu, W. Tags: Cerebrovascular Case Reports Source Type: research