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Infectious Disease: Influenza
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Total 155 results found since Jan 2013.

Factors associated with COVID-19 related hospitalisation, critical care admission and mortality using linked primary and secondary care data
CONCLUSIONS: We confirm that age, sex, ethnicity, obesity, CKD and diabetes are important determinants of risk of COVID-19 hospitalisation or death. For the first time, we also identify people with learning disabilities and multi-morbidity as additional patient cohorts that need to be actively protected during COVID-19 waves.PMID:33942510 | DOI:10.1111/irv.12864
Source: Respiratory Care - May 4, 2021 Category: Respiratory Medicine Authors: Lisa Cummins Irene Ebyarimpa Nathan Cheetham Victoria Tzortziou Brown Katie Brennan Jasmina Panovska-Griffiths Source Type: research

Exercise alters Cardiac Function Independent of Acute Systemic Inflammation in Healthy Men
Am J Physiol Heart Circ Physiol. 2021 Mar 12. doi: 10.1152/ajpheart.00809.2020. Online ahead of print.ABSTRACTAcute elevations in inflammatory cytokines have been demonstrated to increase aortic and left ventricular stiffness and reduce endothelial function in healthy subjects. As vascular and cardiac function are often transiently reduced following prolonged exercise, it is possible that cytokines released during exercise may contribute to these alterations. The a priori aims of this study were to determine if vaccine-induced increases in inflammatory-cytokines would reduce vascular and left ventricular function, whether ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - March 12, 2021 Category: Physiology Authors: Alexandra M Coates Heather L Petrick Philip J Millar Jamie F Burr Source Type: research

Complete Oculomotor Palsy after Influenza Vaccination in a Young Healthy Adult: A Case Report
We present a case report of a 25-year-old woman without any medical history who developed complete oculomotor palsy 2 weeks after influenza vaccination. Other possible causes of oculomotor nerve palsy, such as stroke, compressive lesions, infections, and autoimmune disorders, were eliminated by blood tests, cerebrospinal fluid examination, and imaging studies. Hence, influenza vaccine was considered as the likely cause.Case Rep Neurol 2021;13:35 –39
Source: Case Reports in Neurology - January 25, 2021 Category: Neurology Source Type: research

Relation between respiratory diseases and the development of cardiovascular events in patients with respiratory viral infection
Conclusions: COPD does not seem to be an additional risk factor for the development of CVE in patients with respiratory viral infections. However, patients with CVRF and previous CVE more frequently developed new CVE. Patients with CVRF without COPD developed more CVE.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Zambrano Chacon, M. D. L. A., Esteban-Lucia, L., Izquierdo Perez, A., Nieto Roca, L., Venegas Rodriguez, A. M., Garcia Talavera, C. S., Pello Lazaro, A. M., Acena Navaroo, A., Villar Alvarez, F. Tags: Respiratory infections Source Type: research

PCSK9 monoclonal antibodies for the primary and secondary prevention of cardiovascular disease.
CONCLUSIONS: The evidence for the clinical endpoint effects of  evolocumab and alirocumab were graded as high. There is a strong evidence base to prescribe PCSK9 monoclonal antibodies to people who might not be eligible for other lipid-lowering drugs, or to people who cannot meet their lipid goals on more traditional therapies, which was the main patient population of the available trials.  The evidence base of PCSK9 inhibitors compared with active treatment is much weaker (low very- to low-certainty evidence) and it is unclear whether evolocumab or alirocumab might be effectively used as replacement therapies. Related...
Source: Cochrane Database of Systematic Reviews - October 20, 2020 Category: General Medicine Authors: Schmidt AF, Carter JL, Pearce LS, Wilkins JT, Overington JP, Hingorani AD, Casas JP Tags: Cochrane Database Syst Rev Source Type: research

Johnson & Johnson Reports 2020 Third-Quarter Results
New Brunswick, N.J. (October 13, 2020) – Johnson & Johnson (NYSE: JNJ) today announced results for third-quarter 2020. “Our third-quarter results reflect solid performance and positive trends across Johnson & Johnson, powered by better-than-expected procedure recovery in Medical Devices, growth in Consumer Health, and continued strength in Pharmaceuticals,” said Alex Gorsky, Chairman and Chief Executive Officer. “I am proud of the relentless passion and Credo-led commitment to patients and customers that our colleagues around the world continue to demonstrate as we boldly fight the COVID-19 pandemic. Our wo...
Source: Johnson and Johnson - October 13, 2020 Category: Pharmaceuticals Tags: Our Company Source Type: news

Risk of dementia in patients with periodontitis and related protective factors: a nationwide retrospective cohort study.
CONCLUSIONS: Periodontitis was a risk factor for dementia, while the use of statins and metformin may reduce the risk of dementia. PMID: 32991015 [PubMed - as supplied by publisher]
Source: Journal of Clinical Periodontology - September 28, 2020 Category: Dentistry Authors: Lee CY, Chang CC, Lin CS, Yeh CC, Hu CJ, Wu CZ, Chen TL, Liao CC Tags: J Clin Periodontol Source Type: research

African Americans Struggle With the Current COVID-19
Objectives: Our study aims to explore the differential impact of this pandemic on clinical presentations and outcomes in African Americans (AAs) compared to white patients. Background: AAs have worse outcomes compared to whites while facing heart diseases, stroke, cancer, asthma, influenza and pneumonia, diabetes, and HIV/AIDS. However, there is no current study to show the impact of COVID-19 pandemic on the AA communities. Methods: This is a retrospective study that included patients with laboratory-confirmed COVID-19 from 2 tertiary centers in New Orleans, LA. Clinical and laboratory data were collected. Multivar...
Source: Annals of Surgery - August 22, 2020 Category: Surgery Tags: COVID PAPERS Source Type: research

Opportunistic screening for atrial fibrillation by clinical pharmacists in UK general practice during the influenza vaccination season: A cross-sectional feasibility study
ConclusionsThis study demonstrates that AF screening performed by GP practice –based pharmacists was feasible, economically viable, and positively endorsed by participants. Furthermore, diagnosis of AF by the clinical pharmacist using anSLECG was more sensitive and more specific than the use of pulse palpation alone. Future research should explore the key barriers preventing the adoption of national screening programmes.
Source: PLoS Medicine - July 16, 2020 Category: Internal Medicine Authors: Vilius Savickas Source Type: research

Higher Stroke Rate in COVID-19 vs Influenza Higher Stroke Rate in COVID-19 vs Influenza
New study provides further support for as well as more insight on stroke risk associated with COVID-19.Medscape Medical News
Source: Medscape Cardiology Headlines - July 7, 2020 Category: Cardiology Tags: Neurology & Neurosurgery News Source Type: news