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Total 8013 results found since Jan 2013.

Factors Associated with Antiretroviral Therapy Adherence Among a Community-Based Sample of Sexual Minority Older Adults with HIV
This study utilized a stochastic search variable selection (SVSS) approach to explore potential psychosocial and structural factors associated with HIV-related health outcomes among a community-based sample of older sexual minorities (N  = 150) in South Florida, an U.S. HIV-epidemic epicenter. After SVSS, a forward entry regression approach suggested unstable housing, illicit substance use, current nicotine use, and depression were all associated with poorer ART adherence among older sexual minority adults living with HIV. No a ssociations between potential correlates and biological measures of HIV disease severity wer...
Source: AIDS and Behavior - September 23, 2023 Category: Infectious Diseases Source Type: research

Telehealth as an Effective Care Delivery Method During the COVID-19 Pandemic for the Rhode Island Behavioral Health Population
This study investigated (1) if telehealth allowed for patients who seek mental health services to maintain visit frequency and (2) if subpopulations were less likely to utilize telehealth. We used descriptive statistics to analyze the change in total number of visits, in-person visits from pre-waiver to post-waiver, and a multivariate linear regression to identify relationships between demographics and telehealth utilization. Participants were able to maintain the frequency of visits during the COVID-19 pandemic. Race/ethnicity, age, gender, employment status, and housing status were all statistically significant predictor...
Source: Community Mental Health Journal - September 22, 2023 Category: Psychiatry Authors: Demetria Flowers Emily Goodspeed Mackenzie Daly Source Type: research

Is cervical dysplasia a major concern in women with inflammatory bowel disease? A Spanish retrospective study
Rev Esp Enferm Dig. 2023 Sep 21. doi: 10.17235/reed.2023.9890/2023. Online ahead of print.ABSTRACTCervical cancer (CC) is the fourth most common cancer affecting women worldwide. The risk of women immunosuppressed due to AIDS or organ transplantation is well documented, as most cases are caused by persistent human papillomavirus (HPV) infection and immunosuppression can prevent clearing HPV. Although European guidelines advise that inflammatory bowel disease (IBD) women under immunosuppression should be screened for CC as regularly as high-risk patients, quality evidence is lacking in our country. We performed a retrospect...
Source: Cancer Control - September 21, 2023 Category: Cancer & Oncology Authors: Lorena Jara Fern ández Juan Ángel Ferrer Jos é Lázaro Pérez Calle Pilar L ópez Serrano Source Type: research

Barriers and facilitators to implementing advanced HIV disease screening at  a secondary referral hospital -Malawi: a convergent parallel study
CONCLUSION: The study has identified major contextual barriers to AHD screening including knowledge gap, poor communication systems and inadequate supporting resources. Improving uptake of AHD screening services would therefore require overcoming the existing barriers by adopting a comprehensive approach in developing barrier-tailored strategies.PMID:37730619 | DOI:10.1186/s12913-023-10009-5
Source: Cell Research - September 20, 2023 Category: Cytology Authors: Brany Mithi Agatha Bula Lester Kapanda Fatsani Ngwalangwa Evanson Z Sambala Source Type: research

HIV viral load suppression among people with mental disorders at two urban HIV clinics in Uganda: a parallel convergent mixed methods study using the social ecological model
CONCLUSION AND RECOMMENDATIONS: HIV VLS among PLHIV with mental disorders at institutions that provide integrated HIV and mental health care is still below the UNAIDS 95% target. Health promotion messaging focusing on benefits of VLS and countering stigma to create a safe environment; and active involvement of family members in care could improve HIV treatment outcomes for PLHIV with mental disorders.PMID:37726822 | DOI:10.1186/s12981-023-00567-3
Source: AIDS Research and Therapy - September 19, 2023 Category: Infectious Diseases Authors: Regina Ndagire Rachel Nante Wangi Kevin Ouma Ojiambo Joanita Nangendo Juliet Nakku Herbert Muyinda Fred C Semitala Source Type: research

Amino acid metabolism dysregulation associated with inflammation and insulin resistance in HIV-infected individuals with metabolic disorders
In this study, we performed targeted metabolomic analyses on 64 patients with HIV/AIDS and 21 healthy controls. Twenty-four amino acids and selected intermediate metabolites in the serum were quantitatively detected using high-performance liquid chromatography-tandem mass spectrometry, and characteristic changes and metabolic pathways were analyzed in HIV-infected patients with different degrees of abnormal glucose and lipid metabolism. Spearman's partial correlation was used to analyze the association between amino acids, biochemical parameters, and inflammatory cytokines. The results showed that the main metabolic pathwa...
Source: Amino Acids - September 19, 2023 Category: Biochemistry Authors: Jing Zhang Yanfang Chen Mingli Wang Liuting Zhong Linghua Li Zhongwen Yuan Shangrong Zou Source Type: research

HIV viral load suppression among people with mental disorders at two urban HIV clinics in Uganda: a parallel convergent mixed methods study using the social ecological model
CONCLUSION AND RECOMMENDATIONS: HIV VLS among PLHIV with mental disorders at institutions that provide integrated HIV and mental health care is still below the UNAIDS 95% target. Health promotion messaging focusing on benefits of VLS and countering stigma to create a safe environment; and active involvement of family members in care could improve HIV treatment outcomes for PLHIV with mental disorders.PMID:37726822 | PMC:PMC10510257 | DOI:10.1186/s12981-023-00567-3
Source: AIDS Research and Therapy - September 19, 2023 Category: Infectious Diseases Authors: Regina Ndagire Rachel Nante Wangi Kevin Ouma Ojiambo Joanita Nangendo Juliet Nakku Herbert Muyinda Fred C Semitala Source Type: research

Molecular docking analysis of a virulence factor protein dentilisin from < em > Treponema denticola < /em > with oxazole piperazine derivatives
Bioinformation. 2023 Jan 31;19(1):57-62. doi: 10.6026/97320630019057. eCollection 2023.ABSTRACTDentilisin is a surface protease synthesized by the cell wall of Treponema denticola. This protein aids in the invasion of the periodontal tissue by causing infection. To identify drug molecules that have better results, homology modeling of the dentilisin protein was constructed, and molecular docking was performed with the oxazole compounds (1-6) taken from previous studies that are not yet clinically used. Data shows that compounds 1, 2, 3 show better inhibiting properties.PMID:37720272 | PMC:PMC10504502 | DOI:10.6026/97320630019057
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Kandeeban Parthiban Vishnu Priya Veeraraghavan Surya Sekaran Gayathri Rengasamy Rajalakshmanan Eswaramoorthy Source Type: research

Developing spinal manipulation psychomotor skills competency: A systematic review of teaching methods
CONCLUSION: The use of augmented feedback devices such as human analogue mannequins with force-sensing table technology and computer-connected devices is potentially beneficial in the chiropractic curricula and may facilitate student learning and improvement of spinal manipulation. More studies are required to determine whether psychomotor skill aids translate directly into raised competency levels in novice clinicians.PMID:37721391 | DOI:10.7899/JCE-22-10
Source: The Journal of Chiropractic Education - September 18, 2023 Category: Complementary Medicine Authors: Eleanor de Kock Christopher Yelverton Cornelius Myburgh Source Type: research

Molecular docking analysis of a virulence factor protein dentilisin from < em > Treponema denticola < /em > with oxazole piperazine derivatives
Bioinformation. 2023 Jan 31;19(1):57-62. doi: 10.6026/97320630019057. eCollection 2023.ABSTRACTDentilisin is a surface protease synthesized by the cell wall of Treponema denticola. This protein aids in the invasion of the periodontal tissue by causing infection. To identify drug molecules that have better results, homology modeling of the dentilisin protein was constructed, and molecular docking was performed with the oxazole compounds (1-6) taken from previous studies that are not yet clinically used. Data shows that compounds 1, 2, 3 show better inhibiting properties.PMID:37720272 | PMC:PMC10504502 | DOI:10.6026/97320630019057
Source: Bioinformation - September 18, 2023 Category: Bioinformatics Authors: Kandeeban Parthiban Vishnu Priya Veeraraghavan Surya Sekaran Gayathri Rengasamy Rajalakshmanan Eswaramoorthy Source Type: research

Automated Analysis of Preceptor Comments: A Pilot Study Using Sentiment Analysis to Identify Potential Student Issues in Experiential Education
CONCLUSION: This sentiment analysis algorithm was accurate in capturing positive and negative comments corresponding to pharmacy student performance. Given the accuracy of this preliminary validation for flagging preceptor comments, there are numerous implications when considering the use of sentiment analysis in pharmacy education. Using a sentiment analysis program minimizes the number of qualitative preceptor comments needing review by experiential faculty, as this program can aid in identifying students at risk of progression issues.PMID:37714650 | DOI:10.1016/j.ajpe.2023.02.005
Source: American Journal of Pharmaceutical Education - September 15, 2023 Category: Universities & Medical Training Authors: Kathryn Fuller Carly Lupton-Smith Robert Hubal Jacqueline E McLaughlin Source Type: research