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Therapy: Stem Cell Therapy
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Total 267 results found since Jan 2013.
Impact of a mental training program for pediatric cancer patients after allogeneic hematopoietic stem cell transplantation or high-dose chemotherapy - Results of a randomized controlled trial
Palliat Support Care. 2023 Sep 8:1-8. doi: 10.1017/S1478951523000986. Online ahead of print.ABSTRACTOBJECTIVES: Hematopoietic stem cell transplantation (HSCT) or intensive chemotherapy for the treatment of malignant diseases is a highly distressing experience. The affected person's resilience is crucial to coping with this challenging experience. Experience with resilience-enhancing interventions in children and young adults during cancer therapy is scarce. The major objective of this work was developing and evaluating an effective psycho-oncological mental training that complements the standard psychosocial care.METHODS: ...
Source: Cancer Control - September 8, 2023 Category: Cancer & Oncology Authors: Michaela D öring Johanna Xemaire Dustin Werle Stefanie Thiel Veronika Schneider Sebastian Michaelis Manuel Schl össer Peter Lang Jennifer Svaldi Karin Melanie Cabanillas Stanchi Source Type: research
Identifying a Novel Eight-NK Cell-related Gene Signature for Ovarian Cancer Prognosis Prediction
CONCLUSION: The present study identified a RiskScore signature, which could stratify patients with different infiltration levels, immunotherapy, and chemotherapy drugs. Our study provided a basis for precisely evaluating OVC therapy and prognosis.PMID:37650393 | DOI:10.2174/0929867331666230831101847
Source: Current Medicinal Chemistry - August 31, 2023 Category: Chemistry Authors: Nan Li Kai Yu Delun Huang Hui Zhou Dingyuan Zeng Source Type: research
Fight Aging! Newsletter, August 28th 2023
In conclusion, we identified 20 genes with significant evolutionary signals unique to long-lived species, which provided new insight into the lifespan extension of mammals and might bring new strategies to extend human lifespan.
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Trials of Xenotransplantation of Pig Organs into Humans Continue
https://www.fightaging.org/archives/2023/08/trials-of-xenotransplantation-of-pig-organs-into-humans-continue/
Researchers have genetically engineered pigs to overcome the known barriers to transplantation of pig organs into humans, and have reached the stage of conducting transplants in...
Source: Fight Aging! - August 27, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Identification of Stem Cell-related Gene Markers by Comprehensive Transcriptome Analysis to Predict the Prognosis and Immunotherapy of Lung Adenocarcinoma
CONCLUSION: This study provides insights into the cellular heterogeneity of LUAD and develops a new cancer stemness evaluation indicator and a 4-gene signature as a potential tool for evaluating the response of LUAD to immune checkpoint blockade (ICB) therapy or antineoplastic therapy.PMID:37605423 | DOI:10.2174/1574888X18666230821104844
Source: Current Stem Cell Research and Therapy - August 22, 2023 Category: Stem Cells Authors: Hongzhang Lai Xiwu Wen Yukun Peng Long Zhang Source Type: research
Fight Aging! Newsletter, July 31st 2023
In conclusion, an SBP level below 130 mmHg was found to be associated with longevity among older women. The longer SBP was controlled at a level between 110 and 130 mmHg, the higher the survival probability to age 90. Preventing age-related rises in SBP and increasing the time with controlled BP levels constitute important measures for achieving longevity.
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Source: Fight Aging! - July 30, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues.
Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease
https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/
With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Treating and Managing Urinary Incontinence: Evolving and Potential Multicomponent Medical and Lifestyle Interventions
Res Rep Urol. 2023 Jun 17;15:193-203. doi: 10.2147/RRU.S387205. eCollection 2023.ABSTRACTIncontinence is defined by either ICS 2002 or IUGA/ICS 2010 as the involuntary loss of urine and includes urgency urinary incontinence (UUI), stress urinary incontinence (SUI) or mixed urinary incontinence (MUI). It has a high worldwide prevalence with an associated impact on quality of life. Despite existing management options for the management of urinary incontinence, patients continue to be troubled by symptoms or side effects of existing treatment. There is therefore a requirement for ongoing research into treatment options for th...
Source: Cell Research - June 23, 2023 Category: Cytology Authors: Rayan Mohamed-Ahmed Annika Taithongchai Ana Sofia da Silva Dudley Robinson Linda Cardozo Source Type: research
Predicting busulfan exposure in patients undergoing hematopoietic stem cell transplantation using machine learning techniques
CONCLUSION: All the ML models can potentially be used to estimate BU AUCss with the aim of facilitating rational use of BU on the individualized level, especially models built by SVR and GBRT algorithms.PMID:37326641 | DOI:10.1080/17512433.2023.2226866
Source: Pharmacological Reviews - June 16, 2023 Category: Drugs & Pharmacology Authors: Dandan Li Jingtong Zhao Baohua Xu You Zheng Maobai Liu Huiping Huang Song Han Xuemei Wu Source Type: research
