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Acupuncture for Post-stroke Shoulder-Hand Syndrome: A Systematic Review and Meta-Analysis
Conclusions: Acupuncture therapy seems effective for motor function, pain relief and activities of daily living in stroke patients with mild SHS, when it is used in combination with rehabilitation. The low certainty of evidence downgrades our confidence in making recommendations to clinical practice. Introduction Shoulder-hand syndrome (SHS) is a common condition among people who have had a stroke, with its reported prevalence ranging from 12% to 49% (1, 2). The main symptoms of SHS include pain, hyperalgesia, joint swelling and limitations in range of motion (ROM) (3). Post-stroke SHS is also named type I complex ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

Comparative Genomics of Thiohalobacter thiocyanaticus HRh1T and Guyparkeria sp. SCN-R1, Halophilic Chemolithoautotrophic Sulfur-Oxidizing Gammaproteobacteria Capable of Using Thiocyanate as Energy Source
Conclusion Comparative genome analysis of halophilic SOB from two distant clusters of Gammaproteobacteria capable of thiocyanate oxidation by the cyanate pathway demonstrated a remarkable difference in their mainstream sulfur oxidation pathway. While the Thiohalobacter, a member of Chromatiales, is oxidizing zero-valent sulfur using the rDSR pathway, common for anaerobic SOB, and thiosulfate by an incomplete Sox pathway, common to most of the aerobic gammaproteobacterial SOB, the Guyparkeria SCN-R1 is using complete Sox pathway, normally present in aerobic alpha- and betaproteobacteria. On the other hand, the system respo...
Source: Frontiers in Microbiology - April 30, 2019 Category: Microbiology Source Type: research

Keeping on Top of NIH-Funded Research You Care the Most About Just Got Easier
Last fall, we launched our newly revamped RePORTER site which made it easy to find information about specific NIH supported grants, investigators, and institutions. Today, we are adding to RePORTER’s functionality with a modernized version of MyRePORTER so you can stay on top of the research you care the most about. With MyRePORTER, you can save searches and set customized weekly email alerts that are sent when new projects are funded or new publications are linked to projects in your search. Email alerts will provide a summary listing of the new items, with hyperlinks to bring you back to MyRePORTER to get more informat...
Source: NIH Extramural Nexus - February 16, 2021 Category: Research Authors: Mike Lauer Tags: blog Open Mike New Resources RePORTER Source Type: funding

Viruses, Vol. 14, Pages 1673: Detection of HIV-1 Transmission Clusters from Dried Blood Spots within a Universal Test-and-Treat Trial in East Africa
vlir Andrew Leigh Brown The Sustainable East Africa Research in Community Health (SEARCH) trial was a universal test-and-treat (UTT) trial in rural Uganda and Kenya, aiming to lower regional HIV-1 incidence. Here, we quantify breakthrough HIV-1 transmissions occurring during the trial from population-based, dried blood spot samples. Between 2013 and 2017, we obtained 549 gag and 488 pol HIV-1 consensus sequences from 745 participants: 469 participants infected prior to trial commencement and 276 SEARCH-incident infections. Putative transmission clusters, with a 1.5% pairwise genetic distance threshold, were inferred ...
Source: Viruses - July 29, 2022 Category: Virology Authors: Emma Pujol-Hodge Jesus Salazar-Gonzalez Deogratius Ssemwanga Edwin Charlebois James Ayieko Heather Grant Teri Liegler Katherine Atkins Pontiano Kaleebu Moses Kamya Maya Petersen Diane Havlir Andrew Leigh Brown Tags: Article Source Type: research

Non-surgical adjunctive interventions for accelerating tooth movement in patients undergoing orthodontic treatment
CONCLUSIONS: The evidence from randomised controlled trials concerning the effectiveness of non-surgical interventions to accelerate orthodontic treatment is of low to very low certainty. It suggests that there is no additional benefit of light vibrational forces or photobiomodulation for reducing the duration of orthodontic treatment. Although there may be a limited benefit from photobiomodulation application for accelerating discrete treatment phases, these results have to be interpreted with caution due to their questionable clinical significance. Further well-designed, rigorous RCTs with longer follow-up periods spanni...
Source: Cochrane Database of Systematic Reviews - June 20, 2023 Category: General Medicine Authors: Ahmed El-Angbawi Grant McIntyre Padhraig S Fleming David Bearn Source Type: research

Enhancing Opioid Treatment Program Patient Continuity of Care through Data Interoperability
Funding Opportunity Number: TI-13-010 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: HealthCFDA Number: 93.243Eligible Applicants Others (see text field entitled "Additional Information on Eligibility" for clarification)Agency Name: HHS-SAMHSClosing Date: Apr 03, 2013Award Ceiling: $50,000Expected Number of Awards: 20Creation Date: Feb 12, 2013Funding Opportunity Description: The Substance Abuse and Mental Health Services Administration (SAMHSA), Center for Substance Abuse Treatment (CSAT) is accepting applications for fiscal year (FY) 2013 Enhancing Opioid T...
Source: Grants.gov - February 14, 2013 Category: Research Tags: Health Source Type: funding

Table of Contents
Abstract Omnibus Spending Bill Passed; SAPT Block Grant Increased, ‘Tap’ Eliminated Leaders Urge Diversified Approach to Advocacy at the State Level Pre‐Conviction Diversion is Best for Outcomes: TASC Report Study Finds Lack of Medicaid Providers May Limit Access to SUD Treatment Drug Courts Found Biased against Methadone, Buprenorphine Briefly Noted State News Names in the News Coming up
Source: Alcoholism and Drug Abuse Weekly - January 18, 2014 Category: Addiction Source Type: research

Memex
Funding Opportunity Number: DARPA-BAA-14-21 Opportunity Category: DiscretionaryFunding Instrument Type: Cooperative AgreementOtherProcurement ContractCategory of Funding Activity: Science and Technology and other Research and DevelopmentCFDA Number: 12.910Eligible Applicants Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Agency Name: DOD-DARPA-I2OClosing Date: Apr 08, 2014Award Ceiling: Expected Number of Awards: Creation Date: Feb 04, 2014Funding Opportunity Description: The Defense Advanced Research Projects...
Source: Grants.gov - February 12, 2014 Category: Research Tags: Science and Technology and other Research and Development Source Type: funding

Systems Science
Funding Opportunity Number: PD-14-8085 Opportunity Category: DiscretionaryFunding Instrument Type: GrantCategory of Funding Activity: Science and Technology and other Research and DevelopmentCFDA Number: 47.041Eligible Applicants Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Agency Name: NSFClosing Date: Feb 17, 2015Award Ceiling: Expected Number of Awards: 15Creation Date: Oct 21, 2014Funding Opportunity Description: The Systems Science (SYS) program supports fundamental research leading to a theoretical fou...
Source: Grants.gov - October 22, 2014 Category: Research Tags: Science and Technology and other Research and Development Source Type: funding

New guidance for treating adolescent SUDs includes focus on buprenorphine
The National Association of State Alcohol and Drug Abuse Directors (NASADAD) has issued practice guidance to adolescent substance use disorder (SUD) treatment services. The purpose of the document is to better inform SUD services for adolescents across the states. NASADAD expects that language in the document can be incorporated into contracts with treatment providers to ensure that evidence‐based, high‐quality treatment is delivered to adolescents ages 12 to 18. The project, which was funded under a subcontract to JBS International, under a Substance Abuse and Mental Health Services Administration (SAMHSA) contract, o...
Source: The Brown University Child and Adolescent Psychopharmacology Update - November 25, 2014 Category: Psychiatry Tags: What's New in Research Source Type: research

Overdose Reversal Drug Now Available To Every U.S. High School Free Of Charge
Any high school in the U.S. that wants to carry an emergency opioid overdose reversal kit will now be able to get one free of charge, thanks to a new initiative announced Monday by the Clinton Foundation and the drug's manufacturer. Adapt Pharma, manufacturers of a nasal-spray form of naloxone, also known as Narcan, has partnered with the Clinton Health Matters Initiative to further expand access to the life-saving drug, the two groups said at the final day of the Clinton Health Matters Initiative Activation Summit. Naloxone is nonaddictive, nontoxic and easy to administer, especially through nasal application. It rev...
Source: Healthy Living - The Huffington Post - January 26, 2016 Category: Consumer Health News Source Type: news

Mundipharma and Orexo to launch opioid dependence treatment Zubsolv outside US
Mundipharma has signed an agreement with Swedish-based pharmaceutical company Orexo to grant exclusive global (ex-US) rights to Mundipharma’s network of independent associated companies for Zubsolv (buprenorphine and naloxone sublingual tablet), for …
Source: Pharmaceutical Technology - July 3, 2016 Category: Pharmaceuticals Source Type: news

How Do We Finish The Job That The Comprehensive Addiction And Recovery Act Started?
There is much to celebrate about the enactment of the Comprehensive Addiction And Recovery Act (CARA), including promising provisions related to treatment and recovery. However, the impact of the new law in terms of its ability to fill the so called treatment gap is severely limited by the minimal level of funding for many of these promising new programs and initiatives to expand evidence-based treatment. Without appropriations, CARA is a powerful statement but not necessarily an actionable plan. The treatment gap refers to the more than 1.2 million people who meet the diagnostic criteria for an opioid use disorder (OUD) b...
Source: Health Affairs Blog - September 12, 2016 Category: Health Management Authors: Richard Frank Tags: Costs and Spending Drugs and Medical Technology Featured Public Health Comprehensive Addiction And Recovery Act Congress medication-assisted treatment opiods Opioid Addiction opioid epidemic prescription drug abuse Source Type: blogs

Systems Science
Funding Opportunity ID: 289094 Opportunity Number: PD-17-8085 Opportunity Title: Systems ScienceOpportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: GrantCategory of Funding Activity: Science and Technology and other Research and DevelopmentCategory Explanation: CFDA Number(s): 47.041Eligible Applicants: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility"Additional Information on Eligibility: Agency Code: NSFAgency Name: National Science FoundationPosted Date: Sep 23, 2016Close Da...
Source: Grants.gov - September 23, 2016 Category: Research Tags: Science and Technology and other Research and Development Source Type: funding

Rural Opioid Use Is Driving A Spike In Babies Born With Drug Addiction
The number of babies born with symptoms of opioid withdrawal spiked between 2004 and 2013, driven by opioid use in rural areas, according to a study published Monday in the journal JAMA Pediatrics. In 2004, rates of infant withdrawal, known as neonatal abstinence syndrome, were roughly similar in rural and urban areas, with about one out of every 1,000 babies born with withdrawal symptoms. By 2013, there were approximately five babies born with NAS for every 1,000 births in urban areas, and eight babies born with NAS for every 1,000 births in rural areas.  Together, this translated to a fivefold increase in NAS b...
Source: Healthy Living - The Huffington Post - December 15, 2016 Category: Consumer Health News Source Type: news