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Addressing racial inequality and its effects on vaccination rate: A trial comparing a pharmacist and peer educational program (MOTIVATE) in diverse older adults
CONCLUSIONS: Both interventions significantly improved knowledge and trust toward vaccination and retained their effect 1 month after the program. The 2 effective community-based education models should be expanded to ensure timely and trusted information is available to educate older adults about vaccine-preventable diseases. Further research is encouraged to assess the long-term cost-effectiveness of these models' utilization on a larger scale. DISCLOSURES: Dr Schafer is an employee of Merck; however, at the time of the project, he was a professor at Thomas Jefferson University. The other authors have no conflicts of int...
Source: Herpes - July 31, 2023 Category: Infectious Diseases Authors: Katherine M Prioli Ayse Akincigil Tarlan Namvar Jocelyn Mitchell-Williams Jason J Schafer Renee C Cunningham Lynn Fields-Harris Megan McCoy Ronald Vertsman Ashley Guesnier Laura T Pizzi Source Type: research

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer's...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Educational interventions for health professionals managing chronic obstructive pulmonary disease in primary care
CONCLUSIONS: The evidence of efficacy was equivocal for educational interventions for health professionals in primary care on the proportion of COPD diagnoses confirmed with spirometry, the proportion of patients with COPD who participate in pulmonary rehabilitation, and the proportion of patients prescribed guideline-recommended COPD respiratory medications. Educational interventions for health professionals may improve influenza vaccination rates among patients with COPD and patient satisfaction with care. The quality of evidence for most outcomes was low or very low due to heterogeneity and methodological limitations of...
Source: Cochrane Database of Systematic Reviews - May 6, 2022 Category: General Medicine Authors: Amanda J Cross Dennis Thomas Jenifer Liang Michael J Abramson Johnson George Elida Zairina Source Type: research

A Multicomponent Health Education Campaign Led by Community Health Workers to Increase Influenza Vaccination among Migrants and Refugees
CONCLUSIONS: CHW-led workshops can be an effective way to increase knowledge about influenza and influenza vaccine. Future curriculum should emphasize the difference between viruses and bacteria, and the use of vaccination for prevention as opposed to treatment for illness.PMID:34814785 | DOI:10.1177/21501327211055627
Source: Primary Care - November 24, 2021 Category: Primary Care Authors: Ileana Maria Ponce-Gonzalez Kathleen Perez Allen D Cheadle Morgan Jade Barry Iverson Michael Leo Parchman Source Type: research

Mind the gap from research laboratory to clinic: Challenges and opportunities for next-generation assays in human diseases
Vaccine. 2021 Aug 5:S0264-410X(21)00964-6. doi: 10.1016/j.vaccine.2021.07.071. Online ahead of print.ABSTRACTModern vaccinology has experienced major conceptual and technological advances over the past 30 years. These include atomic-level structures driving immunogen design, new vaccine delivery methods, powerful adjuvants, and novel animal models. In addition, utilizing advanced assays to learn how the immune system senses a pathogen and orchestrates protective immunity has been critical in the design of effective vaccines and therapeutics. The National Institute of Allergy and Infectious Diseases of the National Institut...
Source: Vaccine - August 9, 2021 Category: Allergy & Immunology Authors: M Patricia D'Souza Amy C Palin Thomas Calder Hana Golding Steven H Kleinstein Erin L Milliken David O'Connor Georgia Tomaras Jon Warren Cesar Boggiano Source Type: research

Fight Aging! Newsletter, February 17th 2020
Discussion of the Evolutionary Genetics of Aging Thymic Involution Contributes to Immunosenescence and Inflammaging The Potential for Exosome Therapies to Treat Sarcopenia Correlations of Mitochondrial DNA Copy Number and Epigenetic Age Measures Evidence for PASK Deficiency to Reduce the Impact of Aging in Mice The Aging Retina, a Mirror of the Aging Brain Evidence for Loss of Capillary Density to be Important in Heart Disease Aspects of Immune System Aging Proceed More Rapidly in Men Deacetylation of the NLRP3 Inflammasome as a Way to Control Chronic Inflammation Transplantation of Senescent Cells is an ...
Source: Fight Aging! - February 16, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Revisiting A & P Learning Outcomes | Episode 54
Host Kevin Patton previews the newly revised HAPS Learning Outcomes for A&P, discussing the goals of the revision and samples a few of the changes. Why is noon a good time to get your flu shot? Are there neurons that actively erase memories? Vaping: why A&P teachers need to keep up with the news.00:42 | Timing of Vaccinations02:36 | Sponsored by HAPS03:04 | Neurons That Erase Memory08:22 | Sponsored by AAA08:47 | Vaping13:45 | Sponsored by HAPI Online Graduate Program14:28 | Revisiting the HAPS Learning Outcomes for A&P41:43 | Staying ConnectedIf you cannot see or activate the audio pla...
Source: The A and P Professor - October 20, 2019 Category: Physiology Authors: Kevin Patton Source Type: blogs

Mass Casualty Decontamination in a Chemical or Radiological/Nuclear Incident with External Contamination: Guiding Principles and Research Needs
Conclusion The GHSI Chemical Events and Radiological/Nuclear Threat Working Groups have identified current challenges to effective casualty decontamination in a mass exposure incident. Application of the guiding principles described here to preparedness, planning, and response activities will help to improve effectiveness of decontamination as well as other aspects of the medical management of casualties in a mass exposure incident, based on our current scientific understanding. Research programs designed to address the priority research needs will strengthen the scientific evidence, upon which further improvements in prep...
Source: PLOS Currents Disasters - November 2, 2015 Category: Global & Universal Authors: Susan M Cibulsky Source Type: research