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Therapy: Stem Cell Therapy

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Total 108 results found since Jan 2013.

Protocol for a feasibility trial (EXPRESS-C-GVHD) for an expressive helping intervention within a support group for cutaneous graft-versus-host-disease
DISCUSSION: The EXPRESS-C-GVHD Trial is a pilot trial and will assess whether a Zoom-based expressive writing intervention within the framework of a support group is feasible and can improve QOL outcomes among individuals with cuGVHD.TRIAL REGISTRATION: The trial is registered under number NCT05694832.PMID:37698591 | DOI:10.1007/s00403-023-02718-y
Source: Cell Research - September 12, 2023 Category: Cytology Authors: Trisha Kaundinya Yae Kye Salma E El-Behaedi Jennifer N Choi Source Type: research

2023 Vascular Research Initiatives Conference: Structural and Immune Cells in Vascular Disease
JVS Vasc Sci. 2023 Jul 10;4:100117. doi: 10.1016/j.jvssci.2023.100117. eCollection 2023.ABSTRACTThe 2023 Vascular Research Initiatives Conference (VRIC) was held in Boston, Massachusetts, and coincided with the first day of Vascular Discovery 2023, hosted by the American Heart Association. VRIC attracts vascular clinicians, surgeon-scientists, and basic science researchers to a common arena to facilitate the exchange of basic and translational science to stimulate and inspire participants to study and find solutions to vascular conditions. The theme of the conference this year was "Structural and Immune Cells in Vascular D...
Source: Atherosclerosis - August 31, 2023 Category: Cardiology Authors: Carly Thaxton Katherine Gallagher Alan Dardik Source Type: research

Polyclonal anti-thymocyte globulins for the prophylaxis of graft-versus-host disease after allogeneic stem cell or bone marrow transplantation in adults
CONCLUSIONS: This systematic review suggests that the addition of ATG during allogeneic SCT probably has little or no influence on overall survival. ATG results in a reduction in the incidence and severity of acute and chronic GvHD. ATG intervention probably slightly increases the incidence of relapse and probably does not affect the non relapse mortality. Graft failure may not be affected by ATG prophylaxis. Analysis of data on adverse events was reported in a narrative manner. A limitation for the analysis was the imprecision in reporting between the studies thereby reducing the confidence in the certainty of evidence.PM...
Source: Cochrane Database of Systematic Reviews - June 21, 2023 Category: General Medicine Authors: Geothy Chakupurakal Paul Freudenberger Nicole Skoetz Hans Ahr Sebastian Theurich Source Type: research

Cell cycle arrest: A breakthrough in the supportive care of older cancer patients
CONCLUSIONS: CCA is a novel proactive approach to the toxicity of chemotherapy of special interest to older patients. At the very least it may prevent all forms of myelotoxicity with a single agent, obviating the risk and cost of polypharmacy. It allows to avoid the complications of myelopoietic growth factors which include severe pain, stem cell competition, bone marrow exhaustion, and hematological malignancies. It may allow the treatment of frail patients with full chemotherapy doses. It is also reasonable to expect that may complications other common and sometimes lethal complications of chemotherapy such as stomatitis...
Source: Cancer Control - April 10, 2023 Category: Cancer & Oncology Authors: Claire Falandry Alan List Lodovico Balducci Source Type: research

Medication adherence among allogeneic haematopoietic stem cell transplant recipients: a systematic review protocol
Introduction Patients receiving a haematopoietic stem cell transplant (HSCT) are subjected to complex oral medications based on prophylactic and immunosuppressive treatments. Adherence to medication plays a role in survival, and medication non-adherence (MNA) is closely associated with graft-versus-host disease and other complications. The aim of this systematic review is to summarise the available evidence regarding prevalence rates of medication adherence, the risk factors of MNA, the effectiveness of interventions to increase medication adherence and the outcomes associated with MNA. Methods and analysis We designed a ...
Source: BMJ Open - December 1, 2022 Category: General Medicine Authors: Visintini, C., Mansutti, I., Palese, A. Tags: Open access, Oncology Source Type: research

A Systematic Literature Review of the Economic Evaluations of Treatments for Patients with Chronic Myeloid Leukemia
ConclusionsIn patients with newly diagnosed chronic myeloid leukemia, imatinib regimens were cost effective, mostly owing to the availability of generics. Nilotinib and dasatinib were generally cost effective as second-line agents for patients who were resistant or intolerant to imatinib. Though progress has been made to better characterize the cost effectiveness of first-line and second-line chronic myeloid leukemia therapies, the paucity of published cost-effectiveness studies of third-line treatments increases the uncertainty associated with economic evaluations of later lines of therapy.
Source: PharmacoEconomics - September 30, 2022 Category: Health Management Source Type: research

Extracorporeal photopheresis versus standard treatment for acute graft-versus-host disease after haematopoietic stem cell transplantation in children and adolescents
CONCLUSIONS: The efficacy of ECP in the treatment of aGvHD in children and adolescents after HSCT is unknown, and its use should be restricted to within the context of RCTs. Such studies should address a comparison of ECP alone or in combination with standard treatment versus standard treatment alone. The 2021 review update brought about no additions to these conclusions.PMID:36166494 | DOI:10.1002/14651858.CD009759.pub4
Source: Cochrane Database of Systematic Reviews - September 27, 2022 Category: General Medicine Authors: Kathrin Buder Matthias Zirngibl Sascha Bapistella Joerg J Meerpohl Brigitte Strahm Dirk Bassler Marcus Weitz Source Type: research

Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Disease 2021
Am J Physiol Lung Cell Mol Physiol. 2022 Jun 28. doi: 10.1152/ajplung.00113.2022. Online ahead of print.ABSTRACTThe 9th biennial conference titled "Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases" was hosted virtually, due to the ongoing COVID-19 pandemic, in collaboration with the University of Vermont Larner College of Medicine, the National Heart, Lung, and Blood Institute, the Alpha-1 Foundation, the Cystic Fibrosis Foundation, and the International Society for Cell & Gene Therapy. The event was held from July 12th through 15th, 2021 with a pre-conference workshop held July 9th. As in pr...
Source: American Journal of Physiology. Lung Cellular and Molecular Physiology - June 28, 2022 Category: Cytology Authors: Laertis Ikonomou Mattias Magnusson Ruben Dries Erica L Herzog Robert Hynds Zea Borok Jin-Ah Park Steven Skolasinski Janette K Burgess Leigh Turner Sarah M Mojarad John E Mahoney Thomas Lynch Mareike Lehmann Victor J Thannickal Jaime L Hook Andrew E Vaugha Source Type: research