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Specialty: Geriatrics
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Total 119 results found since Jan 2013.
Effects of Antiplatelet Agents on Functional Outcome and Cognitive Status in Patients with Acute Ischemic Stroke
Conclusion The use of antiplatelet agents in acute ischemic stroke may have a favorable effect on functional outcome and cognitive status in patients at 3 months poststroke.
Source: International Journal of Gerontology - November 17, 2014 Category: Geriatrics Source Type: research
Delayed-onset dementia after stroke or transient ischemic attack
Discussion Severe SVD contributes importantly to delayed-onset dementia after stroke and/or TIA. Future clinical trials aiming to prevent delayed-onset dementia after stroke and/or TIA should target this high-risk group.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - June 17, 2016 Category: Geriatrics Source Type: research
The current situation on vascular cognitive impairment after ischemic stroke in Changsha
In this study, we determined that the prevalence of VCI was 41.8%. Aging, paraventricular white matter lesion (WML), macroangiopathy, high levels of alcohol, a lack of hobbies, and excessive sleep were risk factors for vascular cognitive impairment no dementia (VCIND). A high level of education, manual-work, low level of alcohol use, regular health checks, a vegetable-based diet, and more fruit and milk were protective factors for VCIND. Living alone, hyperlipidemia, transient ischemic attack, a family history of stroke, and brain atrophy were risk factors of vascular dementia (VD). A high educational level, a vegetable-ba...
Source: Archives of Gerontology and Geriatrics - October 22, 2013 Category: Geriatrics Authors: Qiuyun Tu, Binrong Ding, Xia Yang, Song Bai, Junshi Tu, Xiao Liu, Ranran Wang, Jinghua Tao, Hui Jin, Yiqun Wang, Xiangqi Tang Source Type: research
Converting MMSE to MoCA and MoCA 5 ‐minute protocol in an educationally heterogeneous sample with stroke or transient ischemic attack
ConclusionWe provided 2 methods to convert scores from the MMSE to MoCA and MoCA‐5 min based on a large sample of patients with stroke or TIA having a wide range of education and cognitive levels. The converted scores differentiated patients with cognitive impairment after stroke or TIA with high accuracy.
Source: International Journal of Geriatric Psychiatry - January 2, 2018 Category: Geriatrics Authors: Adrian Wong, Sandra E. Black, Stanley Y.P. Yiu, Lisa W.C. Au, Alexander Y.L. Lau, Yannie O.Y. Soo, Anne Y.Y. Chan, Thomas W.H. Leung, Lawrence K.S. Wong, Timothy C.Y. Kwok, Theodore C.K. Cheung, Kam ‐Tat Leung, Bonnie Y.K. Lam, Joseph S.K. Kwan, Vincent Tags: RESEARCH ARTICLE Source Type: research
Low triiodothyronine syndrome is associated with cognitive impairment in patients with acute ischemic stroke: a prospective cohort study
Cognitive impairment is a common and important consequence of stroke and prominently affects patients ’ quality of life1. With reported prevalence ranging widely from 10-82%2, 3, poststroke cognitive impairment (PSCI) is commonly associated with poor functional outcomes3, reduced quality of life4 and higher risk of recurrent stroke5. However, multiple factors that have been found to lead to the pr ogression of PSCI, including older age, family history, gender, and poor educational status6, are not readily amenable to prevention and treatment7.
Source: The American Journal of Geriatric Psychiatry - July 28, 2018 Category: Geriatrics Authors: Huijun Chen, Yuemin Wu, Guiqian Huang, Weilei He, Shasha Lin, Xingru Zhang, Jincai He Source Type: research
Will unpredictable side effects dim the promise of new Alzheimer ’s drugs?
A sea change is underway in the treatment of Alzheimer’s disease, where for the first time a drug that targets the disease’s pathology and clearly slows cognitive decline has hit the U.S. market. A related therapy will likely be approved in the coming months. As many neurologists, patients, and brain scientists celebrate, they’re also nervously eyeing complications from treatment: brain swelling and bleeding, which in clinical trials affected up to about one-third of patients and ranged from asymptomatic to fatal.
The side effect—amyloid-related imaging abnormalities, or ARIA—remains mysterious. “We don’...
Source: Science of Aging Knowledge Environment - August 2, 2023 Category: Geriatrics Source Type: research
The association between neighborhood socioeconomic status, cardiovascular and cerebrovascular risk factors, and cognitive decline in the Health and Retirement Study (HRS).
CONCLUSIONS: In examining the relationship of cognitive status with various variables, neighborhood socioeconomic status, cardiovascular risk, and cerebrovascular risk persisted across the cognitive trajectory classes.
PMID: 31018653 [PubMed - as supplied by publisher]
Source: Aging and Mental Health - April 24, 2019 Category: Geriatrics Authors: Kuchibhatla M, Hunter JC, Plassman BL, Lutz MW, Casanova R, Saldana S, Hayden KM Tags: Aging Ment Health Source Type: research
Association of stressful life events with incident falls and fractures in older men: the Osteoporotic Fractures in Men (MrOS) Study
Conclusions: in this cohort of older men, stressful life events significantly increased risk of incident falls independent of other explanatory variables, but did not independently increase incident fracture risk.
Source: Age and Ageing - December 12, 2013 Category: Geriatrics Authors: Fink, H. A., Kuskowski, M. A., Marshall, L. M. Tags: Research Papers Source Type: research
Relationship of Demographic and Health Factors to Cognition in Older Adults in the ACTIVE Study
Discussion: Age, education, and race are consistently associated with cognitive performance in this sample of older community-dwelling adults. Diabetes, stroke, and suspected clinical depression had independent but weaker effects on cognition.
Source: Journal of Aging and Health - January 2, 2014 Category: Geriatrics Authors: Rexroth, D. F., Tennstedt, S. L., Jones, R. N., Guey, L. T., Rebok, G. W., Marsiske, M. M., Xu, Y., Unverzagt, F. W. Tags: Articles Source Type: research
Greater Daily Defined Dose of Antihypertensive Medication Increases the Risk of Falls in Older People—A Population‐Based Study
ConclusionHigher dose of antihypertensive medication is independently associated with falls in older people, particularly in those with a history of previous stroke, and with more than three standard units conferring the highest risk.
Source: Journal of the American Geriatrics Society - June 16, 2014 Category: Geriatrics Authors: Michele L. Callisaya, James E. Sharman, Jacqueline Close, Stephen R. Lord, Velandai K. Srikanth Tags: Brief Reports Source Type: research
The Diagnostic Utility of the NINDS-CSN Neuropsychological Battery in Memory Clinics
Conclusion: The NINDS-CSN neuropsychological battery can be applied in memory clinics and effectively discriminate between cognitively intact individuals and those with cognitive impairments of varying severity. Furthermore, level of education should be taken into consideration when choosing protocols with different lengths for cognitive assessment.Dement Geriatr Cogn Disord Extra 2016;6:276-282
Source: Dementia and Geriatric Cognitive Disorders Extra - July 14, 2016 Category: Geriatrics Source Type: research
Pulse Pressure Is Associated With Early Brain Atrophy and Cognitive Decline: Modifying Effects of APOE-ε4
We investigated whether midlife pulse pressure is associated with brain atrophy and cognitive decline, and whether the association was modified by apolipoprotein-E ε4 (APOE-ε4) and hypertension. Participants (549 stroke-free and dementia-free Framingham Offspring Cohort Study participants, age range=55.0 to 64.9 y) underwent baseline neuropsychological and magnetic resonance imaging (subset, n=454) evaluations with 5- to 7-year follow-up. Regression analyses investigated associations between baseline pulse pressure (systolic−diastolic pressure) and cognition, total cerebral volume and temporal horn ventricular volume (...
Source: Alzheimer Disease and Associated Disorders - July 1, 2016 Category: Geriatrics Tags: Original Articles Source Type: research
Physical Activity and Other Determinants of Survival in the Oldest Adults
ConclusionIn the oldest adults, accurate quantification of physical activity may provide important prognostic information. The predictive value of cardiovascular risk factors, except age, male sex, and prior stroke, was confirmed to be negligible. An unexpected inverse association between neck pain and mortality may require further investigation.
Source: Journal of the American Geriatrics Society - November 29, 2016 Category: Geriatrics Authors: Antonio Muscari, Giampaolo Bianchi, Paola Forti, Marco Giovagnoli, Donatella Magalotti, Paolo Pandolfi, Marco Zoli, Tags: Brief Reports Source Type: research
Leisure ‐Time Physical Activity Reduces Total and Cardiovascular Mortality and Cardiovascular Disease Incidence in Older Adults
ConclusionsBaseline LTPA reduces the risk of total and CVD mortality and incident CVD events in older adults independently of the major known CVD risk factors. The protective effect of LTPA is dose dependent.
Source: Journal of the American Geriatrics Society - December 25, 2016 Category: Geriatrics Authors: No ël C. Barengo, Riitta Antikainen, Katja Borodulin, Kennet Harald, Pekka Jousilahti Tags: Clinical Investigation Source Type: research
Subcortical hyperintensities in the cholinergic system are associated with improvements in executive function in older adults with coronary artery disease undergoing cardiac rehabilitation
ConclusionThese results suggest that CAD patients with SH in CH tracts improve less than those without SH in CH tracts, over 48 weeks of cardiac rehabilitation. Thus, SH in CH tracts may contribute to longitudinal cognitive decline following a cardiac event and may represent a vascular risk factor of cognitive decline. © 2017 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons Ltd.
Source: International Journal of Geriatric Psychiatry - May 1, 2017 Category: Geriatrics Authors: Calvin Santiago, Nathan Herrmann, Walter Swardfager, Mahwesh Saleem, Paul I. Oh, Sandra E. Black, Janelle Bradley, Krista L. Lanct ôt Tags: Research Article Source Type: research
