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Drug: Nicotine
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Interventions to increase adherence to medications for tobacco dependence.
CONCLUSIONS: There is some evidence that interventions that devote special attention to improving adherence to smoking cessation medication through providing information and facilitating problem-solving can improve adherence, though the evidence for this is not strong and is limited in both quality and quantity. There is some evidence that such interventions improve the chances of achieving abstinence but again the evidence for this is relatively weak.
PMID: 25914910 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - April 29, 2015 Category: Journals (General) Tags: Cochrane Database Syst Rev Source Type: research
Psychosocial interventions for smoking cessation in patients with coronary heart disease.
CONCLUSIONS: Psychosocial smoking cessation interventions are effective in promoting abstinence up to 1 year, provided they are of sufficient duration. After one year, the studies showed favourable effects of smoking cessation intervention, but more studies including cost-effectiveness analyses are needed. Further studies should also analyse the additional benefit of a psychosocial intervention strategy to pharmacological therapy (e.g. nicotine replacement therapy) compared with pharmacological treatment alone and investigate economic outcomes.
PMID: 26148115 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - July 6, 2015 Category: Journals (General) Authors: Barth J, Jacob T, Daha I, Critchley JA Tags: Cochrane Database Syst Rev Source Type: research
So You've Been Ghosted: Here Are Six Steps to Deal With It
Breaking-up with a person who likes you is never easy. It usually requires having that awkward 'break-up' talk. It's especially difficult when your partner doesn't see it coming. But guess what? There's an app for that! Yes, you read that correctly. Binder is an iOS and Android app that offers a relationship-ending service. Simply enter your partner's name and phone number, and choose from a list of reasons, and Binder does the "Binning" (break-up calls and texts) for you. It's brutally honest and to the point. While using an app to dump someone is impersonal, a more heartless route is the increasingly common act of ghos...
Source: Healthy Living - The Huffington Post - September 10, 2015 Category: Consumer Health News Source Type: news
Can We Create An Artificial Brain?
Dr. Miguel Nicolelis is not the kind of person you’d expect to say that something is impossible. After all, he developed a brain-connected exoskeleton that enabled a paraplegic man to deliver the opening kick at the World Cup last year. He used brain implants to give rats a sixth sense (perception of infrared light). And he connected the minds of monkeys, allowing them to accomplish tasks together -- a technology he says could eventually be used to connect human minds into a "brain net." Yet in his latest book, The Relativistic Brain: How it works and why it cannot be simulated by a Turing machine, the dire...
Source: Healthy Living - The Huffington Post - September 16, 2015 Category: Consumer Health News Source Type: news
Additional behavioural support as an adjunct to pharmacotherapy for smoking cessation.
CONCLUSIONS: Providing behavioural support in person or via telephone for people using pharmacotherapy to stop smoking has a small but important effect. Increasing the amount of behavioural support is likely to increase the chance of success by about 10% to 25%, based on a pooled estimate from 47 trials. Subgroup analysis suggests that the incremental benefit from more support is similar over a range of levels of baseline support.
PMID: 26457723 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - October 12, 2015 Category: Journals (General) Authors: Stead LF, Koilpillai P, Lancaster T Tags: Cochrane Database Syst Rev Source Type: research
Intranasal or transdermal nicotine for the treatment of postoperative pain.
CONCLUSIONS: Based on evidence of generally low quality, nicotine may reduce postoperative pain at 24 hours compared with placebo, but the effects were relatively small (less than 1 point on a 10 point pain scale) and there was substantial heterogeneity in the results of our analyses. Nicotine does not appear to reduce postoperative use of opioids or opioid-related adverse events but probably increases the risk of nausea. More research is needed to determine the effectiveness of nicotine for postoperative pain and to understand the optimal timing, dose, and method of delivery of nicotine.
PMID: 26756459 [PubMed - as s...
Source: Cochrane Database of Systematic Reviews - January 12, 2016 Category: Journals (General) Authors: Matthews AM, Fu R, Dana T, Chou R Tags: Cochrane Database Syst Rev Source Type: research
Taking Stock of Our Existence
By MICHEL ACCAD, MD
My last post was prompted by a reader’s comment where Victor Frankl’s Man’s Search for Meaning and Atul Gawande’s Being Mortal were juxtaposed. Since receiving that message, I have had occasion to notice that others also associate these two books.
For example, both are mentioned positively in this moving article by Dr. Clare Luz about a friend’s suicide, and in these tweets from Dr. Paddy Barrett’s podcast program:
Friends and patients of mine have likewise mentioned these two works to me, expressing praise and testifying to the deep impact the books have had on them.
I suspect t...
Source: The Health Care Blog - February 3, 2016 Category: Consumer Health News Authors: Simon Nath Tags: THCB MICHEL ACCAD Source Type: blogs
Gawande, Frankl, and Why “Less Is More” Is More of the Same
By MICHEL ACCAD, MD
My last post was prompted by a reader’s comment where Victor Frankl’s Man’s Search for Meaning and Atul Gawande’s Being Mortal were juxtaposed. Since receiving that message, I have had occasion to notice that others also associate these two books.
For example, both are mentioned positively in this moving article by Dr. Clare Luz about a friend’s suicide, and in these tweets from Dr. Paddy Barrett’s podcast program:
Friends and patients of mine have likewise mentioned these two works to me, expressing praise and testifying to the deep impact the books have had on them.
I suspect ...
Source: The Health Care Blog - February 3, 2016 Category: Consumer Health News Authors: Simon Nath Tags: THCB MICHEL ACCAD Source Type: blogs
Combined pharmacotherapy and behavioural interventions for smoking cessation.
CONCLUSIONS: Interventions that combine pharmacotherapy and behavioural support increase smoking cessation success compared to a minimal intervention or usual care. Updating this review with an additional 12 studies (5,000 participants) did not materially change the effect estimate. Although trials differed in the details of their populations and interventions, we did not detect any factors that modified treatment effects apart from the recruitment setting. We did not find evidence from indirect comparisons that offering more intensive behavioural support was associated with larger treatment effects.
PMID: 27009521 [P...
Source: Cochrane Database of Systematic Reviews - March 23, 2016 Category: Journals (General) Authors: Stead LF, Koilpillai P, Fanshawe TR, Lancaster T Tags: Cochrane Database Syst Rev Source Type: research
Adjustment disorder and DSM-5: A review.
CONCLUSION: Emotional reactions triggered by life events are responsible for full therapy agendas and for the rush in emergency rooms and hospitals. The reflex when faced with crying, insomnia or suicidal thoughts to give a diagnostic of major depressive disorder s is generally accepted by everyone. The elevated risk to commit suicide and the approved success of remission or healing through treatment (psychotherapy) are two major reasons why several studies promote the importance and the need to identify the adjustment disorder of our patients.
PMID: 27216596 [PubMed - as supplied by publisher]
Source: L Encephale - May 26, 2016 Category: Psychiatry Tags: Encephale Source Type: research
How Science Is Resurrecting the Religious Imagination
As far as we know, there is no cure for death, no ingenious algorithm that can program the mysterious breath which at first gives life its form and then corrodes and withers it. It is in this breathing space between womb and tomb that we love, long and become human.
Advances on the frontiers of science are now testing these limits of the human condition. By raising anew foundational questions of origins and destiny, they are, paradoxically, resurrecting the religious imagination.
Who is to say medical science should not enter the atrium between life and death as agony sets in? Why not meddle in the other end of existenc...
Source: Science - The Huffington Post - June 3, 2016 Category: Science Source Type: news
Love Will Be The Death Of Us
Notes On The End Of My Marriage
Author's note: This is a sincere attempt to learn the end of a relationship, a final love letter, of sorts. Some of the names have been changed and my former partner has consented its publication.
8.2011 -- The Beginning
There is no easy way to masturbate into a small plastic container. I find this out as I approach climax, simultaneously holding the container in place while stoking my erection with the other hand. Truth be told, I don't actually masturbate very often -- perhaps something about the act I continue to find shameful.
Suddenly: a rush of white light and a moment of fleeting ...
Source: Healthy Living - The Huffington Post - June 25, 2016 Category: Consumer Health News Source Type: news
Tobacco smoking and breastfeeding: Effect on the lactation process, breast milk composition and infant development. A critical review.
This article is a review of previous reports about the effects of smoking on the lactation process, breast milk composition and infant development. A systematic search for English language articles published until 2015 was made, using a MEDLINE data. The key search terms were "smoking and breastfeeding", "smoking and lactation", "smoking and milk composition", "nicotine and breast milk". Studies have shown that nicotine levels in breast milk of women who smoke are three times higher than those in the plasma levels. Breast milk volume is reduced and the duration of lactation period is shorter. Smoking causes adverse changes...
Source: Environmental Research - August 10, 2016 Category: Environmental Health Authors: Napierala M, Mazela J, Merritt TA, Florek E Tags: Environ Res Source Type: research
Fight Aging! Newsletter, August 29th 2016
This study demonstrates that TNTs play a significant part in the intercellular transfer of α-synuclein fibrils and reveals the specific role of lysosomes in this process. This represents a major breakthrough in understanding the mechanisms underlying the progression of synucleinopathies. These compelling findings, together with previous reports from the same team, point to the general role of TNTs in the propagation of prion-like proteins in neurodegenerative diseases and identify TNTs as a new therapeutic target to combat the progression of these incurable diseases.
Shorter Period of Rapamycin Treatment in Mice...
Source: Fight Aging! - August 28, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
LGBT residents provide insights to match applicants
Matching for residency programs can be stressful for LGBT applicants. Is it okay to be out? How much should I reveal about my LGBT advocacy work? What should I do if an interviewer tries to determine my sexual orientation indirectly? Five LGBT residents, including one couple, recently took part in a webinar to share their experiences and answer these and other questions LGBT students commonly have before and during the match.
The webinar,Navigating the Residency Match as an LGBT Applicant, co-hosted by the AMA and the American Association of Medical Colleges in August, addressed the rules governing questions that can be a...
Source: AMA Wire - September 6, 2016 Category: Journals (General) Authors: Timothy Smith Source Type: news
