Filtered By:
Drug: Nicotine
Education: Grants

This page shows you your search results in order of date.

Order by Relevance | Date

Total 38 results found since Jan 2013.

One Man ’ s Quest to Heal the Oceans —And Maybe Save the World
Enric Sala—marine ecologist, conservationist, and ocean advocate—is standing under a life-size replica of a Northern Atlantic Right Whale at the natural history museum in Washington, D.C., and the air outside is smudged with wildfire smoke drifting down from Canada. It’s not surprising that Sala wants to talk about the smoke, or about whales. Their poop, however, is an unexpected twist. According to Sala, whale excrement, or, more precisely, the lack of it, has a role to play in the choking miasma that has forced my interview with one of the world’s foremost ocean explorers indoors instead of out on...
Source: TIME: Science - August 24, 2023 Category: Science Authors: Aryn Baker Tags: Uncategorized climate change healthscienceclimate TIME 2030 Source Type: news

Career Conversations: Q & A With Physiologist Elimelda Moige Ongeri
Credit: Courtesy of Dr. Elimelda Moige Ongeri. A career path in science is rarely clear cut and linear, which Elimelda Moige Ongeri, Ph.D., can attest adds to its excitement. She went from working in animal reproductive biology to studying proteins involved in inflammation and tissue injury. Dr. Ongeri is also currently dean of the Hairston College of Health and Human Sciences and professor of physiology at North Carolina Agricultural and Technical State University (NC A&T) in Greensboro. In this interview, she shares details of her career, including a change in research focus to human physiology; her goals for the f...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 14, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Profiles Proteins Source Type: blogs

Multiple endpoint in vitro toxicity assessment of a prototype heated tobacco product indicates substantially reduced effects compared to those of combustible cigarette
This study aimed to compare the aerosol chemistry and in vitro toxicological profiles of two prototype Heated Tobacco Product (p-HTP) variants to the 1R6F Reference Cigarette. In the neutral red uptake screen the p-HTPs were 37-39-fold less potent than 1R6F, in the micronucleus assay, responses to the p-HTPs were 8-22-fold less, and in the Ames test mutagenicity was weak or removed compared to 1R6F. The cardiovascular scratch wound assay revealed 58-fold greater wound healing impairment following exposure to 1R6F smoke extracts than the p-HTPs. Furthermore, in seven cell stress-related high content screening endpoints (cel...
Source: Toxicology in Vitro - November 13, 2022 Category: Toxicology Authors: Fiona Chapman Edgar Trelles Sticken Roman Wieczorek Sarah Jean Pour Ole Dethloff Jessica Budde Kathryn Rudd Elizabeth Mason Lukasz Czekala Fan Yu Liam Simms Thomas Nahde Grant O'Connell Matthew Stevenson Source Type: research

Career Conversations: Q & A with Bioengineer C ésar de la Fuente
Dr. César de la Fuente. Credit: Martí E. Berenguer. “Science provides adventure and excitement every single day. When you’re pushing boundaries, you get to jump into the abyss of new areas. It can be scary, but it’s an incredible opportunity to try to improve our world and people’s lives,” says César de la Fuente, Ph.D., a Presidential Assistant Professor in the Perelman School of Medicine and School of Engineering and Applied Science at the University of Pennsylvania, Philadelphia. Our interview with Dr. de la Fuente highlights his journey of becoming a scientist and his research using artificial intelligen...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - September 21, 2022 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Chemistry, Biochemistry and Pharmacology Bacteria Computational Biology Drug Resistance Medicines Profiles Source Type: blogs

Can former conservation ‘pirates’ help scientists study the oceans?
Laura Sánchez Alòs had been at sea for less than 20 minutes when the motorboats attacked. In late January 2019, the 24-year-old Spanish conservation biologist was on board the Farley Mowat , a former U.S. Coast Guard cutter, in Mexican waters in the northern Gulf of California. She was the ship’s scientist, part of a campaign by the Sea Shepherd Conservation Society to study and protect the vaquita , the world’s smallest porpoise and most endangered marine mammal. Since 2015, the organization had been patrolling this region—and making local fishers increasingly angry. Sánchez Alòs was here t...
Source: Science of Aging Knowledge Environment - June 30, 2022 Category: Geriatrics Source Type: research

NIDCR's Fall 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Fall 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   NIDCR News 5 Q&As About “Oral Health in America: Advances and Challenges” NIDCR issued a brief Q&A regarding details of the forthcoming report Oral Health in America: Advances and Challenges, which will be published in Fall 2021. This comprehensive report will examine improvements in oral health over the past two decades,...
Source: NIDCR Science News - September 1, 2021 Category: Dentistry Source Type: news

NIDCR's Summer 2021 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Summer 2021 E-Newsletter In this issue: NIDCR News Funding Opportunities & Related Notices NIH/HHS News Subscribe to NICDR News Science Advances   Grantee News   NIDCR News NIDCR to Release Report on Oral Health in America As a 20-year follow-up to the seminal Oral Health in America: A Report of the Surgeon General, NIDCR will release Oral Health in America: Advances and Challenges in the fall of 2021. The report will illuminate new directions in the prevention and t...
Source: NIDCR Science News - July 1, 2021 Category: Dentistry Source Type: news

Tenth Circuit Grants Qualified Immunity to Police Who Knowingly Violated the First Amendment
Jay SchweikertTheSupreme Court has repeatedly characterizedqualified immunity as protecting “all but the plainly incompetent or those who knowingly violate the law.” Even taken at face value, that standard of care isdepressingly low, especially with respect to law enforcement —i.e., the profession expressly charged with knowing and enforcing the law. But the Tenth Circuit’s recent decision inFrasier v. Evans illustrates how this oft-repeated maxim is itself highly misleading —because even when police officers do, in fact, know that they are violating someone’s rights, they can still receive qualified immunity.T...
Source: Cato-at-liberty - April 12, 2021 Category: American Health Authors: Jay Schweikert Source Type: blogs

NIDCR's Winter 2020 E-Newsletter
Having trouble viewing this email? View it as a Web page. NIDCR's Winter 2020 E-Newsletter In this issue: NIDCR News Funding Opportunities NIH/HHS News Funding Notices Science Advances Subscribe to NICDR News Grantee News   NIDCR News NIDCR Welcomes New Director Rena D’Souza Rena N. D’Souza, DDS, MS, PhD, was sworn in as the director of NIDCR by NIH Director Francis S. Collins, MD, PhD, on October 13. Prior to joining NIH, Dr. D’Souza was the assistant vice president for academic affairs and education for health sciences at the Unive...
Source: NIDCR Science News - December 4, 2020 Category: Dentistry Source Type: news

Congress Is Getting the Transition to Alternative Payment Models Wrong
By TAYLOR CHRISTENSEN Alternative payment models (APMs) are a hot topic these days, and everyone seems to agree that we need to transition toward them and away from fee for service (FFS). But how should we do it? First, let’s think about this task as government policy makers would think about it. They would probably start by saying, “We need to find a way to give incentives to providers and payers to try out these different APMs.” This would be fairly easy to do through Medicare, so they would create some Medicare APM programs and structure them in a way that makes the benefits of joining large enough th...
Source: The Health Care Blog - September 23, 2020 Category: Consumer Health News Authors: Christina Liu Tags: Health Policy Alternative Payment Model TAYLOR CHRISTENSEN Source Type: blogs

Crystal Structure of the Monomeric Extracellular Domain of α9 Nicotinic Receptor Subunit in Complex With α-Conotoxin RgIA: Molecular Dynamics Insights Into RgIA Binding to α9α10 Nicotinic Receptors
Conclusion The first crystal structure of a human nAChR domain with an α-Ctx is presented. The structure revealed the interactions between α-Ctx RgIA and the (+) side of neuronal nAChR α9-ECD in high detail. Based on the structure of this complex, models of human α9α10 nAChR ECD with fully formed binding sites were constructed with RgIA bound to each of them. Our MD simulations suggest that the favorable binding site of RgIA in the human α9α10 nAChR ECD consists of either α9 or α10 subunits as the (+) side and of an adjacent α9 rather than α10 su...
Source: Frontiers in Pharmacology - April 30, 2019 Category: Drugs & Pharmacology Source Type: research

Genome-Wide Identification and Characterization of the JAZ Gene Family in Rubber Tree (Hevea brasiliensis)
Conclusion Jasmonate signaling plays a vital role in the regulation of secondary laticifer differentiation and natural rubber biosynthesis. In the present study, JAZs, the repressors of jasmonate signaling, are genome-wide identified. Based on the computational analyses and gene expression patterns, HbJAZ5.0 and HbJAZ10.0b might be key regulators of laticifer differentiation whereas HbJAZ8.0b was crucial for regulation of natural rubber biosynthesis in H. brasiliensis. The genome-wide identification of HbJAZs will facilitate the jasmonate signaling-mediated laticifer differentiation and natural rubber biosynthesis in rubb...
Source: Frontiers in Genetics - April 30, 2019 Category: Genetics & Stem Cells Source Type: research

A Convergent Study of Genetic Variants Associated With Crohn ’s Disease: Evidence From GWAS, Gene Expression, Methylation, eQTL and TWAS
Conclusion In summary, we conducted an integrative analysis of genetic, epigenetic, and transcriptomic data in CD. Our approach prioritized candidate genes associated with CD from multi-dimensional data and such methods could be extended to many other complex diseases with multi-dimensional omics data being available. Functional analysis of these CDgenes revealed strong immune response enrichment. We further highlighted the potential involvement of COP9 signalosome in CD and suggested interactions among our CDgenes with CD drug target genes. Data Availability Publicly available datasets were analyzed in this study. The ...
Source: Frontiers in Genetics - April 8, 2019 Category: Genetics & Stem Cells Source Type: research

Weekly Postings
See something of interest? Please share our postings with colleagues in your institutions! Spotlight Only Three Days Left to Apply! Call for Applications to the MLA Research Training Institute (RTI) – Apply by December 1 for this week-long residential workshop that provides librarians and library information professionals with the opportunity to work intensively on research design and planning to conduct research that improves practice and adds to the professional knowledgebase. The workshop will be held in Chicago from July 15–19, 2019. National Network of Libraries of Medicine News The MAR offices will be closed Nove...
Source: NN/LM Middle Atlantic Region Blog - November 28, 2018 Category: Databases & Libraries Authors: Hannah Sinemus Tags: Weekly Postings Source Type: news

The Complex Case for Inpatient Psychiatric Care
Amidst the cat pics and political memes, the images of my former elementary school classmates’ children, now elementary school students themselves, there will be a link to a mental health article smushed in there on my Facebook wall. Sometimes, usually against my better judgment, I click on it, because click-bait is just so deliciously clickable. Today, I made the mistake of clicking on an article written by Noam Shpancer, PhD, a psychologist and professor at Otterbein University. The article detailed the experience of a psychotic loved one who spent a brief time in an inpatient psychiatric hospital. In his piece, origi...
Source: World of Psychology - October 29, 2018 Category: Psychiatry & Psychology Authors: Gabriel Nathan Tags: Schizophrenia Stigma Suicide Trauma Treatment inpatient psychiatric hospitalization involuntary hospitalization Psychiatric Care psychiatric institution Source Type: blogs