• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Controversies In The Pharmacotherapy Of Adolescent Depression
DISCUSSION: Moderate to severe depression should be treated with psychotherapy and/or fluoxetine, the best-supported medication, and treatment-resistant adolescents should always receive combined treatment with psychotherapy. Suicidal ideation, particularly with a plan, should be actively explored before starting an antidepressant, as a reason for the closest monitoring. Emergent suicidality after starting antidepressants, as well as antidepressant-related activation, should also be closely monitored and may lead to antidepressant discontinuation. Although no response to pharmacotherapy and psychotherapy may occur in up to...
Source: Current Pharmaceutical Design - May 27, 2022 Category: Drugs & Pharmacology Authors: Gabriele Masi Source Type: research

Bipolar Disorders: Evaluation and Treatment
Am Fam Physician. 2021 Feb 15;103(4):227-239.ABSTRACTBipolar disorders are common, recurrent mental health conditions of variable severity that are difficult to diagnose. Affected individuals have higher rates of other mental health disorders, substance use disorders, and comorbid chronic medical illnesses. New diagnostic criteria and specifiers with attention on mixed features and anxious distress aid the physician in recognizing episode severity and prognosis. Physicians should consider bipolar disorder in any patient presenting with depression. Pharmacotherapy with mood stabilizers, such as lithium, anticonvulsants, and...
Source: American Family Physician - February 15, 2021 Category: Primary Care Authors: Gabrielle Marzani Amy Price Neff Source Type: research

Recent developments in geriatric psychopharmacology.
Authors: Aftab A, Lam J, Liu F, Ghosh A, Sajatovic M Abstract INTRODUCTION: There is a tremendous growing need to address the burden of geriatric psychiatric disorders. Recent developments relevant to geriatric psychiatry have focused on Alzheimer's disease (AD), severe/refractory depression, and cancer/end of life care. AREAS COVERED: This is a non-systematic, narrative review (databases and websites for search: PubMed, Google Scholar, Medscape, ClinicalTrials.gov; focusing on the last 6 years), and covers developments in disease modifying therapies for AD, diagnostic radiotracers for AD, medications for neuro...
Source: Expert Review of Clinical Pharmacology - January 28, 2021 Category: Drugs & Pharmacology Tags: Expert Rev Clin Pharmacol Source Type: research

Maintaining Rapid Antidepressant Effects Following Ketamine Infusion: A Major Unmet Need.
CONCLUSIONS: This evidence base is insufficient to inform clinical practice. Fortunately, a wide variety of molecular targets exist for this indication. Psychotherapy and exercise may also play a beneficial role. More studies are urgently needed to establish how best to maintain rapid symptom improvement seen with ketamine infusions. PMID: 32023369 [PubMed - in process]
Source: Journal of Clinical Psychiatry - February 7, 2020 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Longitudinal Investigation of Psychotherapy Outcomes (LIPO): Description of the Study Protocol
This study will be conducted in the city of Porto Alegre in the state of Rio Grande do Sul in far-southern Brazil. This region has Portuguese, Italian, German, and African influence. It has a population of 1.4 million, and it is the 10th most populous city in Brazil. Its ethnic distribution is as follows: White (79.2%), Black (10.2%), and Pardo (multiracial) people (10.6%). Its religious distribution is as follows: Catholic (83%), Protestant (9%), and others and atheists (8%). Brazil is a country with a high level of religiosity, and it is common for people to associate improvements in their health as being due to their fa...
Source: Frontiers in Psychiatry - April 7, 2019 Category: Psychiatry Source Type: research

Management of comorbid bipolar disorder and substance use disorders.
CONCLUSIONS: There is a very limited number of pharmacotherapy and an even smaller number of psychosocial interventions. Our review highlights the need for more research in this area and for larger, multisite studies with generalizable samples to provide more definite guidance for clinical practice. PMID: 28301219 [PubMed - as supplied by publisher]
Source: The American Journal of Drug and Alcohol Abuse - March 15, 2017 Category: Addiction Authors: Salloum IM, Brown ES Tags: Am J Drug Alcohol Abuse Source Type: research

Results of the Survey on Who Are the Mentally Ill?
Thank you to everyone who participated!The survey was published on Shrink Rap from December 10, 2013 - December 22, 2013.Respondents were solicited through social media, including blogs, listservs, Facebook, and Twitter.  Respondents were not limited to the United States.  Please note that the survey was not validated.  The data below was pasted directly from the Google "Summary of Responses" with no analysis or interpretation.SummaryAnyone who has seen a therapist is mentally illTrue172%False67698%Anyone who has been in psychotherapy with a psychiatrist is mentally illTrue619%False63091%Anyone who take...
Source: Shrink Rap - January 2, 2014 Category: Psychiatrists and Psychologists Authors: Dinah Source Type: blogs

Psychiatrists: the drug pushers
Is the current epidemic of depression and hyperactivity the result of disease-mongering by the psychiatric profession and big pharma? Does psychiatry have any credibility left at all?A psychiatrist who once "treated" me used to recite this rueful little mantra: "They say failed doctors become psychiatrists, and that failed psychiatrists specialise in drugs." By drugs this psychiatrist meant drugs of addiction – and his "treatment" of me consisted of prescribing Temgesic, a synthetic opiate, as a substitute for the heroin I was more strongly inclined to take. So, he undertook this role: actin...
Source: Guardian Unlimited Science - August 3, 2013 Category: Science Authors: Will Self Tags: The Guardian Mental health Culture Health, mind and body Society Books Drugs Features Science Source Type: news

Where Did the Self Go?
In tomorrow's New York Times Magazine, you can read an article by Linda Logan,  "The Problem With How We Treat Bipolar Disorder."  Ms. Logan writes, in a tender and tragic way, about her own struggle with a severe, treatment-resistant mood disorder, and how her psychiatrists attended to her symptoms, but not to what she calls her loss of self.   Ms. Logan writes: How much insult to the self is done by the symptoms of the disorder and how much by the drugs used to treat it? Paradoxically, psychotropic drugs can induce anxiety, nervousness, impaired judgment, mania, hypomania, hallucinations, feelin...
Source: Shrink Rap - April 27, 2013 Category: Psychiatrists and Psychologists Authors: Dinah Source Type: blogs