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Drug: Lithium
Nutrition: Chloride
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Total 362 results found since Jan 2013.
Partial and Complete Replacement of the Phenyl Group(s) of 1,1,3,3-Tetraphenyl-2,2,4,4-tetrakis(trimethylsilyl)cyclotetrasilane by Chlorine Atom(s)
Chemistry. 2023 Sep 18:e202302479. doi: 10.1002/chem.202302479. Online ahead of print.ABSTRACTThe four phenyl groups of 1,1,3,3-tetraphenyl-2,2,4,4-tetrakis(trimethylsilyl)cyclotetrasilane were partially replaced by chlorine atom(s) by successive treatment with trifluoromethanesulfonic acid and lithium chloride. The replacement of all phenyl groups was carried out with hydrogen chloride in the presence of aluminum chloride. The structural features of the resulting mono-, di-, and tetrachlorocyclotetrasilanes were compared by X-ray crystallography.PMID:37720978 | DOI:10.1002/chem.202302479
Source: Chemistry - September 18, 2023 Category: Chemistry Authors: Shintaro Ishida Yosuke Ishii Tetsuya Fukasawa Soichiro Kyushin Source Type: research
Therapeutic potential of lithium chloride and valproic acid against neuronopathic types of mucopolysaccharidoses through induction of the autophagy process
Arch Biochem Biophys. 2023 Sep 12:109754. doi: 10.1016/j.abb.2023.109754. Online ahead of print.ABSTRACTMucopolysaccharidosis (MPS) is a group of inherited disorders, caused by mutations in the genes coding for proteins involved (directly or indirectly) in glycosaminoglycan (GAG) degradation. A lack or drastically decreased residual activity of a GAG-degrading enzyme leads to the storage of these compounds, thus damaging proper functions of different cells, including neurons. The disease leads to serious psycho-motor dysfunctions and death before reaching the adulthood. Until now, induction of the autophagy process was con...
Source: Archives of Biochemistry and Biophysics - September 14, 2023 Category: Biochemistry Authors: Lidia Gaffke Natalia Firyn Estera Rintz Karolina Pierzynowska Ewa Piotrowska Hanna Mazur-Marzec Grzegorz W ęgrzyn Source Type: research
Silencing PKM2 Attenuates Brain Injury Induced by Status Epilepticus by Inhibiting the AKT/mTOR Pathway and the NLRP3 Inflammasome
Neurochem Res. 2023 Sep 13. doi: 10.1007/s11064-023-04023-6. Online ahead of print.ABSTRACTPKM2 is a glycolytic pyruvate kinase isoenzyme, and its role in neurological diseases has been published. However, the role and mechanism of PKM2 in the process of status epilepticus have not been reported. The purpose of this study is to explore the role and mechanism of PKM2 in epilepsy. Quantitative real-time polymerase chain reaction (qRT-PCR) and western blotting were used to explore the expression of PKM2 in cells. Enzyme-linked immunosorbent assay kits were used to evaluate the level of inflammatory factors. An epilepsy model ...
Source: Neurochemical Research - September 13, 2023 Category: Neuroscience Authors: Xiaoli Cui Ruihua Jia Rui Zhao Ni Ma Feng Jiang Source Type: research
Quantification of lithium in molten chlorides by optical emission spectrometry using a novel molten-salt-electrode microplasma source
Talanta. 2023 Aug 24;266(Pt 2):125111. doi: 10.1016/j.talanta.2023.125111. Online ahead of print.ABSTRACTA new molten-salt-electrode microplasma (MSEMP) source for optical emission spectrometry (OES) was constructed, equipped with a molten salt electrode and a metal hollow tube (fed with helium) counter electrode. The use of the MSEMP-OES for constituent analysis of molten salt was primarily evaluated. The acquirement of characteristic spectral lines of some elements in several molten chloride samples verified the good qualitative ability of the proposed MSEMP-OES. Solid copper was dissolved via charge transfer and excited...
Source: Talanta - August 30, 2023 Category: Chemistry Authors: Zhaoqing Cai Huixiu Chen Meng Gao Zheng Wang Source Type: research
Lithium prevents glucocorticoid ‑induced chondrocyte autophagy: An in vitro study
In conclusion, the present study demonstrated that lithium can prevent glucocorticoid‑induced autophagy by activating the PI3K/AKT/mTOR signaling pathway and preventing the glucocorticoid‑induced decrease in chondrocyte viability.PMID:37594059 | DOI:10.3892/mmr.2023.13070
Source: Molecular Medicine - August 18, 2023 Category: Molecular Biology Authors: Qiuru Wang Wanli Zhang Jian Hu Chengcheng Zhao Lijun Cai Pengde Kang Source Type: research
Facile and efficient chitosan-based hygroscopic aerogel for air dehumidification
Int J Biol Macromol. 2023 Aug 11:126191. doi: 10.1016/j.ijbiomac.2023.126191. Online ahead of print.ABSTRACTSorption dehumidification, as an energy-saving and eco-friendly approach, has been emerging in application for air dehumidification. Here, a prospective method is proposed to prepare biomass-based hygroscopic aerogels that are easily applicable, sustainable, high-efficient, and recyclable. The chitosan-based aerogel with a porous and hydrophilic network acts as the carrier and water reservoir for the uniformly distributed lithium chloride hygroscopic salt, and provides the hygroscopic salt with more liberal water cha...
Source: International Journal of Biological Macromolecules - August 13, 2023 Category: Biochemistry Authors: Xinhong Han Yiwen Xue Rui Lou Shaoqiu Ding Shurong Wang Source Type: research
Changes in expression of mesothelial BBS genes in 2D and 3D after lithium chloride and ammonium sulphate induction of primary cilium disturbance: a pilot study
CONCLUSIONS: These data indicate distinct BBSome molecular profiles in human benign and MPM cells cultured in 2D and 3D dimensions and support the notion that PC genes should be investigated as potential MPM therapeutic targets.PMID:37542187 | DOI:10.1007/s43440-023-00513-0
Source: Pharmacological Reports - August 4, 2023 Category: Drugs & Pharmacology Authors: Erasmia Rouka Rajesh M Jagirdar Ioannis Sarrigeorgiou Eleanna Pitaraki Sotirios I Sinis Charalambos Varsamas Eleftherios D Papazoglou Ourania S Kotsiou Peggy Lymberi Anastasios Giannou Chrissi Hatzoglou Konstantinos I Gourgoulianis Sotirios G Zarogiannis Source Type: research
