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Drug: Polyethylene Glycol
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Total 2716 results found since Jan 2013.
A rapid and simple protocol for concentration of SARS-CoV-2 from sewage
J Virol Methods. 2021 Aug 26;297:114272. doi: 10.1016/j.jviromet.2021.114272. Online ahead of print.ABSTRACTThe aim of this study was to set up a simple protocol to concentrate SARS-CoV-2 from sewage, which can be implemented in laboratories with minimal equipment resources. The method avoids the need for extensive purification steps and reduces the concentration of potential inhibitors of RT-qPCR contained in sewage. The concentration method consists of a single step, in which a small volume (40 mL) of sewage sample is incubated with polyaluminum chloride (PAC)(0.00045 N Al3+ final concentration). Virus particles adsorbed...
Source: Journal of Virological Methods - August 29, 2021 Category: Virology Authors: Diana P Wehrendt Mariana G Mass ó Adri án Gonzales Machuca Claudia V Vargas Melina E Barrios Josefina Campos Dami án Costamagna Luis Bruzzone Daniel M Cisterna N éstor Gabriel Iglesias Viviana A Mbayed Elsa Baumeister Daniela Centr ón Mar ía Paula Q Source Type: research
Polyethylene glycol and polysorbate testing in twelve patients prior to or after COVID-19 vaccine administration
Ann Allergy Asthma Immunol. 2021 Oct 11:S1081-1206(21)01158-3. doi: 10.1016/j.anai.2021.10.009. Online ahead of print.NO ABSTRACTPMID:34648975 | PMC:PMC8505018 | DOI:10.1016/j.anai.2021.10.009
Source: Annals of Allergy, Asthma and Immunology - October 14, 2021 Category: Allergy & Immunology Authors: Taya Carpenter Justin Konig Jillian Hochfelder Subhadra Siegel Melissa Gans Source Type: research
Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension
Mol Med. 2021 Oct 21;27(1):133. doi: 10.1186/s10020-021-00380-6.ABSTRACTAcetylcholine (ACh) decreases blood pressure by stimulating endothelium nitric oxide-dependent vasodilation in resistance arterioles. Normal plasma contains choline acetyltransferase (ChAT) and its biosynthetic product ACh at appreciable concentrations to potentially act upon the endothelium to affect blood pressure. Recently we discovered a T-cell subset expressing ChAT (TChAT), whereby genetic ablation of ChAT in these cells produces hypertension, indicating that production of ACh by TChAT regulates blood pressure. Accordingly, we reasoned that incre...
Source: Molecular Medicine - October 22, 2021 Category: Molecular Biology Authors: Andrew Stiegler Jian-Hua Li Vivek Shah Tea Tsaava Aisling Tynan Huan Yang Yehuda Tamari Michael Brines Kevin J Tracey Sangeeta S Chavan Source Type: research
Allergic reactions to COVID-19 vaccines and addressing vaccine hesitancy: Northwell Health experience
CONCLUSION: Intradermal PEG testing has limited utility in evaluating anaphylaxis to mRNA vaccines. Most severe postvaccination allergic symptoms are not caused by hypersensitivity to PEG. The majority of people with reaction to the initial mRNA vaccine can be safely revaccinated. Patients with anaphylaxis to COVID-19 vaccines benefit from physician-observed vaccination.PMID:34699968 | PMC:PMC8542398 | DOI:10.1016/j.anai.2021.10.019
Source: Annals of Allergy, Asthma and Immunology - October 26, 2021 Category: Allergy & Immunology Authors: Blanka Kaplan Sherry Farzan Gina Coscia David W Rosenthal Alissa McInerney Artemio M Jongco Punita Ponda Vincent R Bonagura Source Type: research
Utility and Futility of Skin Testing to Address Concerns Surrounding mRNA COVID-19 Vaccine Reactions
CONCLUSION: The low positivity rate of COVID-19 vaccine excipient skin testing and high rate of subsequent COVID-19 vaccine tolerance suggests a low utility of this method in evaluation of COVID-19 vaccine hypersensitivity reactions. Focus should shift to the use of existing vaccine allergy practice parameters, with consideration of graded dosing if necessary. Based on these results, strict avoidance of subsequent COVID-19 vaccination should be discouraged.PMID:34798275 | PMC:PMC8594060 | DOI:10.1016/j.anai.2021.11.006
Source: Annals of Allergy, Asthma and Immunology - November 19, 2021 Category: Allergy & Immunology Authors: Mitchell M Pitlick Andrea N Sitek Michael E D'Netto Kelley N Dages Sergio E Chiarella Alexei Gonzalez-Estrada Avni Y Joshi Miguel A Park Source Type: research
Production of Long-Acting CNGRC-CPG2 Fusion Proteins: New Derivatives to Overcome Drug Immunogenicity of Ligand-Directed Enzyme Prodrug Therapy for Targeted Cancer Treatment
Conclusion: We have successfully produced PEGylated-CNGRC-CPG2, which is bioactive and with lower immunogenicity in ligand-directed enzyme prodrug therapy for cancer treatment.PMID:34802309 | PMC:PMC8606725 | DOI:10.1177/15330338211057371
Source: Technology in Cancer Research and Treatment - November 22, 2021 Category: Cancer & Oncology Authors: Layla Al-Mansoori Alanod D Al Qahtani Philip Elsinga Sayed K Goda Source Type: research
Resveratrol-Loaded TPGS-Resveratrol-Solid Lipid Nanoparticles for Multidrug-Resistant Therapy of Breast Cancer: < em > In Vivo < /em > and < em > In Vitro < /em > Study
In conclusion, the findings of the present study indicate significant potential for use of TPGS-Res-SLNs as an efficient drug delivery vehicle to overcome drug resistance in breast cancer therapy.PMID:34950642 | PMC:PMC8688991 | DOI:10.3389/fbioe.2021.762489
Source: Cell Research - December 24, 2021 Category: Cytology Authors: Wenrui Wang Mengyang Zhou Yang Xu Wei Peng Shiwen Zhang Rongjie Li Han Zhang Hui Zhang Shumin Cheng Youjing Wang Xinyu Wei Chengxu Yue Qingling Yang Changjie Chen Source Type: research
Factors influencing recovery of SARS-CoV-2 RNA in raw sewage and wastewater sludge using polyethylene glycol-based concentration method
In conclusion, our modified PEG-based concentration method can cut down the analysis time at least by half, which in turn helps to implement early detection system for SARS-CoV-2 in wastewater.PMID:35027874 | PMC:PMC8730514 | DOI:10.7171/jbt.21-3203-012
Source: Journal of Biomolecular Techniques : JBT - January 14, 2022 Category: Molecular Biology Authors: Kamruzzaman Khan Scott W Tighe Appala Raju Badireddy Source Type: research
Biocompatible chitosan/polyethylene glycol/multi-walled carbon nanotube composite scaffolds for neural tissue engineering
J Zhejiang Univ Sci B. 2022 Jan 15;23(1):58-73. doi: 10.1631/jzus.B2100155.ABSTRACTCarbon nanotube (CNT) composite materials are very attractive for use in neural tissue engineering and biosensor coatings. CNT scaffolds are excellent mimics of extracellular matrix due to their hydrophilicity, viscosity, and biocompatibility. CNTs can also impart conductivity to other insulating materials, improve mechanical stability, guide neuronal cell behavior, and trigger axon regeneration. The performance of chitosan (CS)/polyethylene glycol (PEG) composite scaffolds could be optimized by introducing multi-walled CNTs (MWCNTs). CS/PEG...
Source: J Zhejiang Univ Sci ... - January 14, 2022 Category: Science Authors: Shengbo Sang Rong Cheng Yanyan Cao Yayun Yan Zhizhong Shen Yajing Zhao Yanqing Han Source Type: research
