A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research

Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017.ABSTRACTAs the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated is...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Keith J M Moore Jeremy Cahill Guy Aidelberg Rachel Aronoff Ali Bekta ş Daniela Bezdan Daniel J Butler Sridar V Chittur Martin Codyre Fernan Federici Nathan A Tanner Scott W Tighe Randy True Sarah B Ware Anne L Wyllie Evan E Afshin Andres Bendesky Connie Source Type: research

A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research

Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017.ABSTRACTAs the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated is...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Keith J M Moore Jeremy Cahill Guy Aidelberg Rachel Aronoff Ali Bekta ş Daniela Bezdan Daniel J Butler Sridar V Chittur Martin Codyre Fernan Federici Nathan A Tanner Scott W Tighe Randy True Sarah B Ware Anne L Wyllie Evan E Afshin Andres Bendesky Connie Source Type: research

A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research

Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017.ABSTRACTAs the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated is...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Keith J M Moore Jeremy Cahill Guy Aidelberg Rachel Aronoff Ali Bekta ş Daniela Bezdan Daniel J Butler Sridar V Chittur Martin Codyre Fernan Federici Nathan A Tanner Scott W Tighe Randy True Sarah B Ware Anne L Wyllie Evan E Afshin Andres Bendesky Connie Source Type: research

A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research

Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017.ABSTRACTAs the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated is...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Keith J M Moore Jeremy Cahill Guy Aidelberg Rachel Aronoff Ali Bekta ş Daniela Bezdan Daniel J Butler Sridar V Chittur Martin Codyre Fernan Federici Nathan A Tanner Scott W Tighe Randy True Sarah B Ware Anne L Wyllie Evan E Afshin Andres Bendesky Connie Source Type: research

A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research

Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017.ABSTRACTAs the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated is...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Keith J M Moore Jeremy Cahill Guy Aidelberg Rachel Aronoff Ali Bekta ş Daniela Bezdan Daniel J Butler Sridar V Chittur Martin Codyre Fernan Federici Nathan A Tanner Scott W Tighe Randy True Sarah B Ware Anne L Wyllie Evan E Afshin Andres Bendesky Connie Source Type: research

A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research

Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017.ABSTRACTAs the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated is...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Keith J M Moore Jeremy Cahill Guy Aidelberg Rachel Aronoff Ali Bekta ş Daniela Bezdan Daniel J Butler Sridar V Chittur Martin Codyre Fernan Federici Nathan A Tanner Scott W Tighe Randy True Sarah B Ware Anne L Wyllie Evan E Afshin Andres Bendesky Connie Source Type: research

A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research

Loop-Mediated Isothermal Amplification Detection of SARS-CoV-2 and Myriad Other Applications
J Biomol Tech. 2021 Sep;32(3):228-275. doi: 10.7171/jbt.21-3203-017.ABSTRACTAs the second year of the COVID-19 pandemic begins, it remains clear that a massive increase in the ability to test for SARS-CoV-2 infections in a myriad of settings is critical to controlling the pandemic and to preparing for future outbreaks. The current gold standard for molecular diagnostics is the polymerase chain reaction (PCR), but the extraordinary and unmet demand for testing in a variety of environments means that both complementary and supplementary testing solutions are still needed. This review highlights the role that loop-mediated is...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Keith J M Moore Jeremy Cahill Guy Aidelberg Rachel Aronoff Ali Bekta ş Daniela Bezdan Daniel J Butler Sridar V Chittur Martin Codyre Fernan Federici Nathan A Tanner Scott W Tighe Randy True Sarah B Ware Anne L Wyllie Evan E Afshin Andres Bendesky Connie Source Type: research

A Rapid, Isothermal, and Point-of-Care System for COVID-19 Diagnostics
J Biomol Tech. 2021 Sep;32(3):221-227. doi: 10.7171/jbt.21-3203-019.ABSTRACTThe COVID-19 pandemic has had a profound, detrimental effect on economies and societies worldwide. Where the pandemic has been controlled, extremely high rates of diagnostic testing for the SARS-CoV-2 virus have proven critical, enabling isolation of cases and contact tracing. Recently, diagnostic testing has been supplemented with wastewater measures to evaluate the degree to which communities have infections. Whereas much testing has been done through traditional, centralized, clinical, or environmental laboratory methods, point-of-care testing h...
Source: Journal of Biomolecular Techniques : JBT - February 9, 2022 Category: Molecular Biology Authors: Christopher Mozsary Duncan McCloskey Kristina M Babler Juan Boza Daniel Butler Benjamin Currall Sion Williams Anne Wiley Evan E Afshin George S Grills Mark E Sharkey Prem Premsrirut Helena Solo-Gabriele Yoslayma Cardentey David Erickson Christopher E Maso Source Type: research