Filtered By:
Drug: Aspirin
This page shows you your search results in order of relevance. This is page number 9.
Order by Relevance | Date
Total 5446 results found since Jan 2013.
Genetic variants associated with drugs‐induced immediate hypersensitivity reactions: a PRISMA‐compliant systematic review
This article is protected by copyright. All rights reserved.
Source: Allergy - December 1, 2015 Category: Allergy & Immunology Authors: Abderrahim Oussalah, Cristobalina Mayorga, Miguel Blanca, Annick Barbaud, Alla Nakonechna, Josefina Cernadas, Maia Gotua, Knut Brockow, Jean‐Christophe Caubet, Andreas Bircher, Marina Atanaskovic, Pascal Demoly, Luciana Kase‐Tanno, Ingrid Terreehorst, Tags: Review Source Type: research
Chemoprevention of colorectal neoplasia
ConclusionsCurrently, there is not enough evidence to support the implementation of a chemopreventative agent for general use. However, there appears to be a role for aspirin in selected subgroups.
Source: ANZ Journal of Surgery - December 21, 2015 Category: Surgery Authors: Chris Wakeman, Jacqueline Keenan, Jimmy Eteuati, Paul Hollington, Tim Eglinton, Frank Frizelle Tags: Original Article Source Type: research
Pharmacological treatment for Buerger's disease.
CONCLUSIONS: Moderate quality evidence suggests that intravenous iloprost (prostacyclin analogue) is more effective than aspirin for eradicating rest pain and healing ischaemic ulcers in Buerger's disease, but oral iloprost is not more effective than placebo. Verylow and low quality evidence suggests there is no difference between prostacyclin (iloprost and clinprost) and the prostaglandin analogue alprostadil for healing ulcers and relieving pain respectively in severe Buerger's disease. Very-low quality evidence suggests there is no difference in pain scores and amputation rates between folic acid and placebo, in people ...
Source: Cochrane Database of Systematic Reviews - February 1, 2016 Category: Journals (General) Authors: Cacione DG, Baptista-Silva JC, Macedo CR Tags: Cochrane Database Syst Rev Source Type: research
Omega-3 fatty acids as an adjunct for periodontal therapy—a review
Conclusions
Dietary supplementation with fish oil could be a cost-effective adjunctive therapy to the management of periodontal disease.
Clinical relevance
The host modulatory properties of omega-3 fatty acids warrant further assessment of their use as an adjunct in the management of periodontitis.
Source: Clinical Oral Investigations - February 17, 2016 Category: Dentistry Source Type: research
Oral aspirin for treating venous leg ulcers.
CONCLUSIONS: Low quality evidence from two trials indicate that there is currently insufficient evidence for us to draw definitive conclusions about the benefits and harms of oral aspirin on the healing and recurrence of venous leg ulcers. We downgraded the evidence to low quality due to potential selection bias and imprecision due to the small sample size. The small number of participants may have a hidden real benefit, or an increase in harm. Due to the lack of reliable evidence, we are unable to draw conclusions about the benefits and harms of oral daily aspirin as an adjunct to compression in VLU healing or recurrence....
Source: Cochrane Database of Systematic Reviews - February 18, 2016 Category: Journals (General) Authors: de Oliveira Carvalho PE, Magolbo NG, De Aquino RF, Weller CD Tags: Cochrane Database Syst Rev Source Type: research
Pharmacological treatment for Buerger's disease.
CONCLUSIONS: Moderate quality evidence suggests that intravenous iloprost (prostacyclin analogue) is more effective than aspirin for eradicating rest pain and healing ischaemic ulcers in Buerger's disease, but oral iloprost is not more effective than placebo. Verylow and low quality evidence suggests there is no difference between prostacyclin (iloprost and clinprost) and the prostaglandin analogue alprostadil for healing ulcers and relieving pain respectively in severe Buerger's disease. Very-low quality evidence suggests there is no difference in pain scores and amputation rates between folic acid and placebo, in people ...
Source: Cochrane Database of Systematic Reviews - March 11, 2016 Category: Journals (General) Authors: Cacione DG, Macedo CR, Baptista-Silva JC Tags: Cochrane Database Syst Rev Source Type: research
Abstract 203: Preventing Stroke in Patients With Atrial Fibrillation: A Review of Published Interventions to Aid Patient Decision Making Session Title: Abstract Poster Session II
Conclusion: Interventions designed to aid patient decision making around stroke prevention in AF improved a selection of patient-centered outcomes. Given the availability of multiple NOACs and an implantable device for stroke prevention in AF, there is a need to develop and evaluate new patient decision support tools.
Source: Circulation: Cardiovascular Quality and Outcomes - February 26, 2016 Category: Cardiology Authors: ONeill, E. S., Grande, S. W., Elwyn, G., Coylewright, M. Tags: Session Title: Abstract Poster Session II Source Type: research
Antiplatelet versus anticoagulation treatment for patients with heart failure in sinus rhythm.
CONCLUSIONS: There is evidence from RCTs to suggest that neither oral anticoagulation with warfarin or platelet inhibition with aspirin is better for mortality in systolic heart failure with sinus rhythm (high quality of the evidence for all-cause mortality and moderate quality of the evidence for non-fatal cardiovascular events and major bleeding events). Treatment with warfarin was associated with a 20% reduction in non-fatal cardiovascular events but a twofold higher risk of major bleeding complications (high quality of the evidence). We saw a similar pattern of results for the warfarin versus clopidogrel comparison (lo...
Source: Cochrane Database of Systematic Reviews - September 14, 2016 Category: Journals (General) Authors: Shantsila E, Lip GY Tags: Cochrane Database Syst Rev Source Type: research
Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy.
CONCLUSIONS: In this second update, we confirmed that primary thromboprophylaxis with LMWH significantly reduced the incidence of symptomatic VTE in ambulatory cancer patients treated with chemotherapy. In addition, the uLMWH semuloparin, which is not commercially available, significantly reduced the incidence of symptomatic VTE. The risk of major bleeding associated with LMWH, while not reaching statistical significance, suggest caution and mandate additional studies to determine the risk-to-benefit ratio of LMWH in this setting. Despite the encouraging results of this review, routine prophylaxis in ambulatory cancer pati...
Source: Cochrane Database of Systematic Reviews - November 30, 2016 Category: Journals (General) Authors: Di Nisio M, Porreca E, Candeloro M, De Tursi M, Russi I, Rutjes AW Tags: Cochrane Database Syst Rev Source Type: research
QUESTION 1: What is the best therapy for children with Kawasaki disease who fail to respond to initial intravenous immunoglobulin?
Scenario A 7-year-old girl was admitted with Kawasaki disease (KD), and treated with aspirin and intravenous immunoglobulin (Ig) therapy. After 48 hours of treatment she is still miserable and febrile, and you wonder what would be the most effective next step in treatment to reduce the risk of her developing coronary artery aneurysms. Structured clinical question In patients with KD who fail to respond to initial intravenous Ig therapy (population), what is the most effective next line of treatment (intervention) to reduce the risk of coronary artery aneurysm development (outcome)? SearchCochrane library: 0 relevant P...
Source: Archives of Disease in Childhood - December 13, 2016 Category: Pediatrics Authors: van Hasselt, T. J., Wacogne, I. D. Tags: ADC Archimedes Source Type: research
Current and future perspectives on the treatment of cerebral ischemia.
Authors: Christophe BR, Mehta SH, Garton AL, Sisti J, Connolly ES
Abstract
INTRODUCTION: After heart disease and combined forms of cancer, stroke is the leading cause of death in the United States. Currently, tissue-plasminogen activator (tPA) thrombolysis is the only thrombolytic therapy that has been shown to improve patient outcome. Presently, the only antithrombotic drug treatment that has proven effective at improving acute ischemic stroke patient outcome is aspirin administration. Despite these studies, no clinical trials have yet demonstrated a reliably effective pharmacological treatment. Areas covered: We ...
Source: Expert Opinion on Pharmacotherapy - April 11, 2017 Category: Drugs & Pharmacology Tags: Expert Opin Pharmacother Source Type: research
Clopidogrel plus aspirin versus aspirin alone for preventing cardiovascular events.
CONCLUSIONS: The available evidence demonstrates that the use of clopidogrel plus aspirin in people at high risk of cardiovascular disease and people with established cardiovascular disease without a coronary stent is associated with a reduction in the risk of myocardial infarction and ischaemic stroke, and an increased risk of major and minor bleeding compared with aspirin alone. According to GRADE criteria, the quality of evidence was moderate for all outcomes except all-cause mortality (low quality evidence) and adverse events (very low quality evidence).
PMID: 29240976 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - December 14, 2017 Category: General Medicine Authors: Squizzato A, Bellesini M, Takeda A, Middeldorp S, Donadini MP Tags: Cochrane Database Syst Rev Source Type: research
Fight Aging! Newsletter, March 12th 2018
This study identifies the missing link between Lewy bodies and the type of damage that's been observed in neurons affected by Parkinson's. Parkinson's is a disorder of the mitochondria, and we discovered how Lewy bodies are releasing a partial break-down product that has a high tropism for the mitochondria and destroys their ability to produce energy."
Lewy bodies were described a century ago, but it was not until 1997 that scientists discovered they were made of clumps of a misfolded protein called α-synuclein. When it's not misfolded, α-synuclein is believed to carry out functions related to the transmission of...
Source: Fight Aging! - March 11, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
The Emerging Role of Inflammation in Cardiovascular Disease.
CONCLUSIONS: Patients with elevated inflammatory markers such as hsCRP are at risk for ASVCD events. Several drug classes have shown the ability to decrease hsCRP levels, but the extent to which this reduces ASCVD events in lieu of other drug mechanisms was not clear. Canakinumab specifically targets the inflammatory process in ASCVD and was proven to be effective in preventing ASCVD events in patients with elevated hsCRP levels.
PMID: 29557210 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - March 1, 2018 Category: Drugs & Pharmacology Authors: Martinez BK, White CM Tags: Ann Pharmacother Source Type: research
Fight Aging! Newsletter, May 7th 2018
The objective here is a set of tests that (a) match up to the expected outcome based on human trials of mitochondrially targeted antioxidants, and (b) that anyone can run without the need to involve a physician, as that always adds significant time and expense. These tests are focused on the cardiovascular system, particularly measures influenced by vascular stiffness, and some consideration given to parameters relevant to oxidative stress and the development of atherosclerosis.
A standard blood test, with inflammatory markers.
An oxidized LDL cholesterol assessment.
Resting heart rate and blood pressure.
Heart r...
Source: Fight Aging! - May 6, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
