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Prophylaxis for Venous Thromboembolic Events in Elective Total Hip and Total Knee Arthroplasty
Curr Pharm Des. 2022 Apr 18. doi: 10.2174/1381612828666220418090928. Online ahead of print.ABSTRACTVenous thromboembolism (VTE) is a serious complication after major orthopaedic operations, such as a total hip (THA) and knee (TKA) arthroplasty. Therefore, perioperative VTE prophylaxis is recommended; a multitude of modern options are available, including both pharmacologic (aspirin, unfractionated and lowmolecular-weight heparin, vitamin K antagonists, and novel oral anticoagulants) and/or mechanical interventions (early mobilization, graduated compression stockings, intermittent pneumatic compression devices, and venous f...
Source: Current Pharmaceutical Design - April 20, 2022 Category: Drugs & Pharmacology Authors: Theofilos Karasavvidis Vasileios Bouris William Xiang Georgios Tzavellas Nektarios Charisis Leonidas Palaiodimos Vassiliki Kigka Christos Bourantas Ioannis Gkiatas Source Type: research

Stroke Prevention in Symptomatic Large Artery Intracranial Atherosclerosis Practice Advisory: Report of the AAN Guideline Subcommittee
Neurology. 2022 Mar 22;98(12):486-498. doi: 10.1212/WNL.0000000000200030.ABSTRACTBACKGROUND AND OBJECTIVES: To review treatments for reducing the risk of recurrent stroke or death in patients with symptomatic intracranial atherosclerotic arterial stenosis (sICAS).METHODS: The development of this practice advisory followed the process outlined in the American Academy of Neurology Clinical Practice Guideline Process Manual, 2011 Edition, as amended. The systematic review included studies through November 2020. Recommendations were based on evidence, related evidence, principles of care, and inferences.MAJOR RECOMMENDATIONS: ...
Source: Atherosclerosis - March 22, 2022 Category: Cardiology Authors: Tanya N Turan Osama O Zaidat Gary S Gronseth Marc I Chimowitz Antonio Culebras Anthony J Furlan Larry B Goldstein Nestor R Gonzalez Julius G Latorre Steven R Mess é Thanh N Nguyen Rajbeer S Sangha Michael J Schneck Aneesh B Singhal Lawrence R Wechsler Al Source Type: research

Characteristics of Adult Severe Refractory Asthma in Korea Analyzed From the Severe Asthma Registry.
CONCLUSIONS: The baseline characteristics of severe asthma patients in the Korea Severe Asthma Registry were analyzed and reported for the first time. With this cohort, further prospective studies should be performed to search for ways to improve management of severe refractory asthma. PMID: 30479076 [PubMed]
Source: Allergy, Asthma and Immunology Research - November 29, 2018 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research

Opioids are associated with venous leg ulcer healing
Introduction: Not all venous leg ulcers (VLUs) heal with standard compression therapy. The search for adjunctive therapies is ongoing, with agents such as aspirin, pentoxifylline and statins suggested as potential options. We performed a secondary analysis of 3 large randomized clinical trials and sought to find a relationship between healing rates of VLUs and various oral medications.
Source: Journal of the American Academy of Dermatology - May 31, 2017 Category: Dermatology Source Type: research

Factors linked to disease severity and time to remission in patients with chronic spontaneous urticaria
ConclusionAlthough the described markers are promising, further studies on representative and well characterized patient populations are needed to determine the value of these clinical and biological markers for predicting the severity and course of disease in patients with CSU.This article is protected by copyright. All rights reserved.
Source: Journal of the European Academy of Dermatology and Venereology - February 28, 2017 Category: Dermatology Authors: Mario S ánchez‐Borges, Fernan Caballero‐Fonseca, Arnaldo Capriles‐Hulett, Luis González‐Aveledo, Marcus Maurer Tags: Review Article Source Type: research

Is Teaching Meditation The New Bartending?
...there may actually be puritanical fanatics of conscience who even prefer to lie down and die on a certain nothing than an uncertain something. ~ Nietzsche ...every artist first attains the supreme pinnacle of his greatness when he can look down into himself and his art, when he can laugh at himself. ~ Nietzsche I found the recent "F*ck That" meditation video to be a skillful skewering of the spate of self-anointed meditation teachers. Since there is no unanimously accepted meditation teacher training certification or licensure program, anyone can call himself a "Meditation Teacher" with that title currently being as leg...
Source: Healthy Living - The Huffington Post - February 2, 2016 Category: Consumer Health News Source Type: news

The Acute Treatment of Migraine in Adults: The American Headache Society Evidence Assessment of Migraine Pharmacotherapies
The study aims to provide an updated assessment of the evidence for individual pharmacological therapies for acute migraine treatment. Pharmacological therapy is frequently required for acutely treating migraine attacks. The American Academy of Neurology Guidelines published in 2000 summarized the available evidence relating to the efficacy of acute migraine medications. This review, conducted by the members of the Guidelines Section of the American Headache Society, is an updated assessment of evidence for the migraine acute medications. A standardized literature search was performed to identify articles related to acute ...
Source: Headache: The Journal of Head and Face Pain - January 20, 2015 Category: Neurology Authors: Michael J. Marmura, Stephen D. Silberstein, Todd J. Schwedt Tags: American Headache Society Evidence Assessment Source Type: research

The acute treatment of migraine in adults: the american headache society evidence assessment of migraine pharmacotherapies.
Abstract The study aims to provide an updated assessment of the evidence for individual pharmacological therapies for acute migraine treatment. Pharmacological therapy is frequently required for acutely treating migraine attacks. The American Academy of Neurology Guidelines published in 2000 summarized the available evidence relating to the efficacy of acute migraine medications. This review, conducted by the members of the Guidelines Section of the American Headache Society, is an updated assessment of evidence for the migraine acute medications. A standardized literature search was performed to identify articles...
Source: Headache - January 1, 2015 Category: Neurology Authors: Marmura MJ, Silberstein SD, Schwedt TJ Tags: Headache Source Type: research

Do You Believe More Vaccines or Better Nutrition Prevents Disease?
Conclusion Tremendous government financial and medical resources are wasted on the development of more vaccinations to prevent diseases. No research has proven the effectiveness of vaccinations in preventing illness. Overwhelming evidence exists to show vaccines are dangerous to health and contribute to illness, injury and death. To prevent disease, one should avoid vaccinations, mercury dental fillings and toxic food. Following a nutrient-dense diet of whole, organic foods and removing toxic metals from the body are the best avenues to try and prevent illness and enhance health. References http://www.fierce...
Source: vactruth.com - December 20, 2013 Category: Health Medicine and Bioethics Commentators Authors: Michelle Goldstein Tags: Michelle Goldstein Top Stories Dr. Russell Blaylock National Institutes of Health (NIH) Nutrition truth about vaccines Weston Price Source Type: blogs

Aspirin for the Prophylaxis of Venous Thromboembolic Events in Orthopedic Surgery Patients: A Comparison of the AAOS and ACCP Guidelines with Review of the Evidence.
CONCLUSIONS: Recent changes to both the ACCP and AAOS guidelines are in agreement for those who choose to use aspirin for chemoprophylaxis of VTE. Current surgical care improvement project measures do not include aspirin as an appropriate sole option for the prevention of VTE, but in patients undergoing elective TKA or who have a contraindication to pharmacologic prophylaxis and undergo a THA or HFS, aspirin in conjunction with compression devices as part of a multimodal approach would meet these measures. Data do not support the hypothesis that aspirin is less likely to cause adverse bleeding events than more potent antic...
Source: The Annals of Pharmacotherapy - January 1, 2013 Category: Drugs & Pharmacology Authors: Stewart DW, Freshour JE Tags: Ann Pharmacother Source Type: research