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Drug: Metformin
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Total 6410 results found since Jan 2013.
Impact of Chinese Herbal Medicine on Glucolipid Metabolic Outcomes in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis
CONCLUSION: Compared with the placebo group, Chinese herbal medicine had positive effects on glucolipid metabolism in women with PCOS. Chinese herbal medicine had a positive effect on lipid metabolism when the control group was metformin, but no effect on glucose metabolism. These findings need to be verified in high-quality, large-sample, randomized controlled trials in the future.PMID:36212945 | PMC:PMC9546672 | DOI:10.1155/2022/3245663
Source: Evidence-based Complementary and Alternative Medicine - October 10, 2022 Category: Complementary Medicine Authors: Jie Li Ruqun Zheng Zixin Lin Fangyuan Hu Ying Lin Guomei Zeng Jieni Fang Yingyan Shen Huiyan Tan Mei Han Juan Li Source Type: research
The efficacy of Da Chaihu decoction combined with metformin tablets for type 2 diabetes mellitus: A systematic review and meta-analysis
CONCLUSIONS: Very low-quality research shows that Da Chaihu decoction combined with metformin tablets exert a certain level of efficacy on patients with type 2 diabetes compared with metformin alone. However, random sequence generation methodology was reported in five studies leading to the low quality of the included studies. None of the six studies depicted the blinding method, allocation concealment, selective reporting, and assessed the purity and potency of the product. This observation requires verification through high-quality, multi-center, double-blinded randomized controlled trials, and assesses the purity and po...
Source: Complementary Therapies in Medicine - October 23, 2022 Category: Complementary Medicine Authors: Jia-Bin Wang Yan-Xia Wang Fen Li Yan-Fei Li Xing-Li Li Pei-Yao Huang Chen Wang Meng Wang Jie Qiu Ke-Hu Yang Wen-Wen Qiu Lu Liu Bao-Hong Mao Hong-Pu Li Xu-Dong Liu Fu-Yun Li Xu-Dong Cui Peng-Ju Wang Wen-Bo Liu Source Type: research
Nephrological management and drug dosing in patients with rheumatic diseases and renal insufficiency
CONCLUSION: The antirheumatic medication should be modified and a complex nephroprotective treatment concept is mandatory in the management of patients with rheumatic disease and renal insufficiency, that in the best-case scenario can be guaranteed by a close interdisciplinary cooperation of rheumatologists and nephrologists.PMID:36350405 | DOI:10.1007/s00393-022-01283-5
Source: Zeitschrift fur Rheumatologie - November 9, 2022 Category: Rheumatology Authors: Stefan M Weiner Source Type: research
Metanalyses on metformin's role in pancreatic cancer suffer from severe bias and low data quality - An umbrella review
CONCLUSIONS: Meta-analyses describing the association of metformin use in patients with pancreatic cancer are plagued by various types of bias inherent in retrospective studies. The quality of evidence linking metformin to decreased pancreatic cancer mortality is generally low.PMID:36697348 | DOI:10.1016/j.pan.2023.01.007
Source: Cancer Control - January 25, 2023 Category: Cancer & Oncology Authors: Zuzanna Nowicka Anna Matyjek Katarzyna P łoszka Mateusz Łaszczych Wojciech Fendler Source Type: research
Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials
CONCLUSION: Inositol is an effective and safe treatment in PCOS. Moreover, inositols showed non-inferiority in most outcomes compared to the gold standard treatment; metformin.TRIAL REGISTRATION: PROSPERO registration number: CRD42021283275.PMID:36703143 | DOI:10.1186/s12958-023-01055-z
Source: Reproductive Biology - January 26, 2023 Category: Reproduction Medicine Authors: Dorina Greff Anna E Juh ász Szil árd Váncsa Alex V áradi Zolt án Sipos Julia Szinte Sunjune Park P éter Hegyi P éter Nyirády N ándor Ács Szabolcs V árbíró Eszter M Horv áth Source Type: research
Metformin: A Promising Radiosensitizer in Neoadjuvant Rectal Cancer Treatment
CONCLUSION: Metformin might constitute a highly promising radiosensitizer in neoadjuvant LARC treatment attracting much scientific interest. Due to the lack of studies with high evidence, further advanced research is required to enhance the existing knowledge about its potential value in this field.PMID:37132307 | DOI:10.2174/1574887118666230428114349
Source: Reviews on Recent Clinical Trials - May 3, 2023 Category: Cancer & Oncology Authors: Nikolaos S Georgopoulos Maria Tolia Davide Mauri Konstantinos Kamposioras Nikolaos Charalampakis Nikolaos Tsoukalas Areti Gkantaifi Source Type: research
