Filtered By:
Drug: Gammagard Liquid

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 38 results found since Jan 2013.

Aquaporin-4 autoantibodies increase vasogenic edema formation and infarct size in a rat stroke model
Background: Neuromyelitis optica (NMO) is an autoimmune disorder of the central nervous system, which is characterized by autoantibodies directed against the water channel aquaporin-4 (AQP4). As one of the main water regulators in the central nervous system, APQ4 is supposed to be involved in the dynamics of brain edema. Cerebral edema seriously affects clinical outcome after ischemic stroke; we therefore aimed to investigate whether NMO-antibodies may exert the same functional effects as an AQP4-inhibitor in-vivo in acute ischemic stroke. Methods: Sixteen male Wistar rats were randomized into two groups twice receiving ei...
Source: BMC Immunology - May 20, 2015 Category: Allergy & Immunology Authors: Martin JuenemannTobias BraunSimone DoengesMax NedelmannClemens MuellerGeorg BachmannPratibha SinghFranz BlaesTibo GerrietsMarlene Tschernatsch Source Type: research

Chart validation of inpatient ICD-9-CM administrative diagnosis codes for ischemic stroke among IGIV users in the Sentinel Distributed Database
The Sentinel Distributed Database (SDD) is a large database of patient-level medical and prescription records, primarily derived from insurance claims and electronic health records, and is sponsored by the U.S. Food and Drug Administration for drug safety assessments. In this chart validation study, we report on the positive predictive value (PPV) of inpatient ICD-9-CM acute ischemic stroke (AIS) administrative diagnosis codes (433.x1, 434.xx, and 436) in the SDD. As part of an assessment of the risk of thromboembolic adverse events following treatment with intravenous immune globulin (IGIV), charts were obtained for 131 ...
Source: Medicine - December 1, 2017 Category: Internal Medicine Tags: Research Article: Diagnostic Accuracy Study Source Type: research

Intravenous immune globulin and thromboembolic adverse events: A systematic review and meta‐analysis of RCTs
This article is protected by copyright. All rights reserved.
Source: American Journal of Hematology - March 11, 2016 Category: Hematology Authors: Eric M. Ammann, Cole B. Haskins, Kelsey M. Fillman, Rebecca L. Ritter, Xiaomei Gu, Scott K. Winiecki, Ryan M. Carnahan, James C. Torner, Bruce H. Fireman, Michael P. Jones, Elizabeth A. Chrischilles Tags: Research Article Source Type: research

Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association.
CONCLUSIONS: These recommendations provide updated and best evidence-based guidance to healthcare providers who diagnose and manage Kawasaki disease, but clinical decision making should be individualized to specific patient circumstances. PMID: 28356445 [PubMed - as supplied by publisher]
Source: Circulation - March 29, 2017 Category: Cardiology Authors: McCrindle BW, Rowley AH, Newburger JW, Burns JC, Bolger AF, Gewitz M, Baker AL, Jackson MA, Takahashi M, Shah PB, Kobayashi T, Wu MH, Saji TT, Pahl E, American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council Tags: Circulation Source Type: research

Bleeding Related Episodes, Thrombotic Events and Platelet Counts Among Immune Thrombocytopenia Patients Receiving Second Line Therapy
CONCLUSIONS: This retrospective real world evidence study compares mean platelet response and burden of both BREs and TEs in ITP patients treated with different second-line treatments. Although there were significant differences in mean platelet counts achieved with the second-line treatments, TEs were observed with similar incidence across all treatments. Patients who received splenectomy had the highest mean platelet counts and also the highest proportion of patients who experienced TEs, though differences in TEs did not reach statistical significance. Incidence proportion of patients with BREs was lower in patients trea...
Source: Blood - November 21, 2018 Category: Hematology Authors: Said, Q., Lal, L. S., Andrade, K., Nezami, B., Graves, J. A., Roy, A., Cuker, A. Tags: 311. Disorders of Platelet Number or Function: Poster II Source Type: research

Optic neuritis in CD59 deficiency: an extremely rare presentation
CONCLUSION: Although it is a rarely reported disease, better recognition of CD59 deficiency by pediatric neurologists is necessary because it is curable. In addition to different presentations reported, optic neuritis may also be a manifestation of CD59 deficiency.PMID:36082655 | DOI:10.24953/turkjped.2021.1405
Source: The Turkish Journal of Pediatrics - September 9, 2022 Category: Pediatrics Authors: Çağatay Günay Elvan Yard ım Elif Ya şar Ayse Semra H ız-Kurul Gamze Sar ıkaya Uzan Taylan Öztürk Aylin Yaman Ulu ç Yiş Source Type: research