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Total 93 results found since Jan 2013.

Weissella koreensis and Pediococcus pentosaceus bacterial ghosts induce inflammatory responses as immunostimulants
In this study, bacterial ghosts (BGs) were generated from Weissella koreensis LKS42 (WKorGs) and Pediococcus pentosacues KA94 (PPGs) by chemically inducing lysis using substances such as hydrochloric acid (HCl), sulfuric acid (H2SO4), nitric acid (HNO3), acetic acid (CH3COOH), sodium hydroxide (NaOH), potassium hydroxide (KOH), sodium carbonate (Na2CO3), n-butanol, and C6H8O7. HCl-induced WKorGs and PPGs exhibited complete removal of DNA and displayed transverse membrane dissolution tunnel structures under scanning electron microscopy (SEM). Cell viability assays showed high viability of RAW 264.7 cells exposed to HCl-indu...
Source: Biochemical and Biophysical Research communications - August 19, 2023 Category: Biochemistry Authors: Jieun Lee Kwang-Su Lee Junwon Lee Ki-Sung Lee Shin-Young Park Source Type: research

Effects of deacetylation degree of chitosan on the structure of aerogels
Int J Biol Macromol. 2023 Aug 3:126123. doi: 10.1016/j.ijbiomac.2023.126123. Online ahead of print.ABSTRACTChitosan aerogels, obtained by (supercritical) CO2 drying of hydrogels, are novel adsorbents because of their large surface area and high porosity. Intrinsic properties of chitosan such as molecular weight (MW) and degree of deacetylation (DDA) had large impacts on the characteristics of chitosan aerogels. Although there are a few studies about the effects of solely DDA or MW on aerogel structure, none of them has focused on the mutual effects. The study aims to investigate the combined effects of MW and DDA of chitos...
Source: International Journal of Biological Macromolecules - August 5, 2023 Category: Biochemistry Authors: Serap Namli Ozge Guven Feyza Nur Simsek Anton Gradi šek Gulum Sumnu Meryem Esra Yener Mecit Oztop Source Type: research

A drug-incorporated-microparticle-eggshell-membrane-scaffold (DIMES) dressing: a novel biomaterial for localised wound regeneration
This study aimed to develop a biocompatible bandage made of drug-incorporated poly (lactic-co-glycolic acid) (PLGA) microparticles (MPs) and eggshell membrane (ESM) for cornea wound healing. ESM has desirable properties for wound healing and can be isolated from eggshells using acetic acid or ethylenediaminetetraacetic acid (EDTA) protocols. Fluorescein isothiocyanate-labelled Bovine Serum Albumin (FITC-BSA) was used as a model drug, and the PLGA MPs were fabricated using a solvent extraction method. The MPs were successfully attached to the fibrous layer of the ESM using NaOH. The surface features of the ESM samples conta...
Source: European Journal of Pharmaceutics and Biopharmaceutics - July 18, 2023 Category: Drugs & Pharmacology Authors: Rosemond A Mensah Michael T Cook Stewart B Kirton Victoria Hutter David Ys Chau Source Type: research

Impact of Bacillus species on Fe reduction of kaolin in bioleaching: surface, structural, and chemical studies
Appl Microbiol Biotechnol. 2023 Jun 14. doi: 10.1007/s00253-023-12622-0. Online ahead of print.ABSTRACTConventional techniques to remove Fe impurities in kaolin typically involve high environmental impact and cost. Alternative methods have been focused on the use of bioleaching where Fe in kaolin is reduced with microorganisms. Early results established a noticeable effect of the bacteria on the redox state of Fe, but knowledge gaps persist such as details on the bacterial-kaolin interactions during attachment of bacteria onto kaolin surface, the metabolites produced by bacteria, and changes in Fe(II)/Fe(III) ion equilibri...
Source: Applied Microbiology and Biotechnology - June 14, 2023 Category: Microbiology Authors: Shih Nee Yong Wei Sheong Lee Sylvia Chieng Steven Lim Seng How Kuan Source Type: research

Antimicrobial activity and chemical profile of wood vinegar from eucalyptus (Eucalyptus urophylla x Eucalyptus  grandis - clone I144) and bamboo (Bambusa vulgaris)
The objectives of the present work were to evaluate the antibacterial and antifungal action of two kinds of wood vinegar (WV), one ofEucalyptus urograndis wood and another ofBambusa vulgaris biomass, and determine their chemical profile. The antimicrobial effect was assessed againstStaphylococcus aureus,Pseudomonas aeruginosa,Salmonella enteritidis,Escherichia coli,Streptococcus agalactiae, andCandida albicans. The minimum inhibitory concentration and the minimum bactericidal and fungicidal concentrations were determined. Micrographs of the microorganisms before and after exposure to both kinds of wood vinegar were obtaine...
Source: World Journal of Microbiology and Biotechnology - May 8, 2023 Category: Microbiology Source Type: research

Early changes of fecal short-chain fatty acid levels in patients with mild cognitive impairments
CONCLUSION: Reductions in fecal SCFAs were observed in patients with MCI compared with NC. Reduced fecal SCFAs were negatively associated with Aβ deposition in cognition-related brain regions in MCI group. Our findings suggest that gut metabolite SCFAs have the potential to serve as early diagnostic biomarkers for distinguishing patients with MCI from NC and could serve as potential targets for preventing AD.PMID:37144597 | DOI:10.1111/cns.14252
Source: CNS Neuroscience and Therapeutics - May 5, 2023 Category: Neuroscience Authors: Chao Gao Binyin Li Yixi He Pai Huang Juanjuan Du Guiying He Pingchen Zhang Huidong Tang Shengdi Chen Source Type: research

Synthesis and characterization of pendant N,N-dimethylaminobenzaldehyde-functionalized chitosan Schiff base composite (CS@MABA) as a new sorbent for removal of Pb(II) ions from aqueous media
Int J Biol Macromol. 2023 Apr 27:124642. doi: 10.1016/j.ijbiomac.2023.124642. Online ahead of print.ABSTRACTIn this work, new pendant N,N-dimethylaminobenzaldehyde-functionalized chitosan Schiff base composite (CS@MABA) was prepared from the simple and convenient condensation reaction between chitosan (CS) and N,N-dimethylaminobenzaldehyde (MABA) in ethanol-glacial acetic acid (1:1 v/v) and characterized by Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), differential scanning calorimetry (DSC) and scanning electron microscope (SEM). The as-prepared composite CS@MABA was applied for the removal of ...
Source: International Journal of Biological Macromolecules - April 29, 2023 Category: Biochemistry Authors: Fang Yang Xingxing Yang Kaimin Su Yun He Qing Lin Source Type: research