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Total 5504 results found since Jan 2013.

Continued challenges in pediatric anesthesia during COVID-19 in 2022: An international survey from the pediatric anesthesia COVID-19 collaborative
CONCLUSION: Our study found that COVID-19 has continued to impact pediatric anesthesiology. There are major discrepancies between what anesthesiologists believe are important for job satisfaction and faculty retention compared to implemented initiatives. Data from this survey provide insight for institutions and departments for addressing these challenges.PMID:37732382 | DOI:10.1111/pan.14762
Source: Pain Physician - September 21, 2023 Category: Anesthesiology Authors: John Zhong Victoria Bradford Allison M Fernandez Andrew Infosino Codruta N Soneru Steven J Staffa Vidya T Raman Joseph Cravero David Zurakowski Petra M Meier Pediatric Anesthesia COVID-19 Collaborative Source Type: research

Decoding COVID-19 Vaccine Hesitancy Using Multiple Regression Analysis with Socioeconomic Values
Proc Int Conf Adv Inf Netw Appl. 2023;655:649-659. doi: 10.1007/978-3-031-28694-0_61. Epub 2023 Mar 15.ABSTRACTWith the growth and development of COVID-19 and its variants, reaching a level of herd immunity is critically important for national security in public health. To deal with COVID-19, the United States has implemented phased plans to distribute COVID-19 vaccines. As of November 2022, over 80% of Americans had received their first shot to guard against COVID-19, and 68.6% were considered fully vaccinated, according to the dataset provided by CDC. However, a significant number of American people still hesitate to rec...
Source: Adv Data - September 18, 2023 Category: Epidemiology Authors: Wei Lu Ling Xue Bria Shorten Source Type: research

Explaining the U.S. rural disadvantage in COVID-19 case and death rates during the Delta-Omicron surge: The role of politics, vaccinations, population health, and social determinants
We describe differences in COVID-19 case and mortality rates across the rural-urban continuum during Wave 4 of the COVID-19 pandemic. Using a progressive modeling approach, we evaluate the relative contribution of a range of explanatory factors for the rural disadvantage we observe, including: pre-pandemic population health composition, vaccination rates, political partisanship, socioeconomic composition, access to broadband internet rate, and primary care physicians per capita. Results show that rural counties had higher observed burdens of cases and deaths in Wave 4 compared to more urban counties. The most remote rural ...
Source: Rural Remote Health - September 15, 2023 Category: Rural Health Authors: Malia Jones Mahima Bhattar Emma Henning Shannon M Monnat Source Type: research

Evolution of HIV virulence in response to disease-modifying vaccines: A modeling study
Vaccine. 2023 Sep 13:S0264-410X(23)01027-7. doi: 10.1016/j.vaccine.2023.08.071. Online ahead of print.ABSTRACTPathogens face a tradeoff with respect to virulence; while more virulent strains often have higher per-contact transmission rates, they are also more likely to kill their hosts earlier. Because virulence is a heritable trait, there is concern that a disease-modifying vaccine, which reduces the disease severity of an infected vaccinee without changing the underlying pathogen genotype, may result in the evolution of higher pathogen virulence. We explored the potential for such virulence evolution with a disease-modif...
Source: Vaccine - September 15, 2023 Category: Allergy & Immunology Authors: Molly C Reid John E Mittler James T Murphy Sarah E Stansfield Steven M Goodreau Neil Abernethy Joshua T Herbeck Source Type: research

Self-assembling Gn head ferritin nanoparticle vaccine provides full protection from lethal challenge of < em > Dabie bandavirus < /em > in aged ferrets
This study demonstrates that DBV GnH-FT nanoparticles provide an efficient vaccine efficacy in mouse and aged ferret models and should be an outstanding vaccine candidate targeted for the aged population against fatal DBV infection. IMPORTANCE Dabie bandavirus (DBV) is an emerging tick-borne virus that causes severe fever with thrombocytopenia syndrome (SFTS) in infected patients. Human SFTS symptoms progress from fever, fatigue, and muscle pain to the depletion of white blood cells and platelets with fatality rates up to 30%. The recent spread of its vector tick to over 20 states in the United States increases the potenti...
Source: Cancer Control - September 15, 2023 Category: Cancer & Oncology Authors: Dokyun Kim Eunha Kim Semi Kim Youseung Chung Chih-Jen Lai Inho Cha Sung-Dong Cho Yunseo Choi Xinghong Dai Stephanie Kim Seokmin Kang Mi-Jeong Kwak Ziyi Liu Younho Choi Su-Hyung Park Young Ki Choi Jae U Jung Source Type: research

Arbovirology and Cold War Collaborations: A Transnational History of the Tick-borne Encephalitis Vaccine, 1930-1980
This article analyzes the history of immunization against tick-borne encephalitis (TBE) and specifically the processes that led to the creation and application of TBE vaccines in the Soviet Union and Austria. Rather than presenting the development of TBE vaccines from the perspective of national scientific schools, the article investigates their history as a transnational project, focusing on the connections among the Soviet Union, Czechoslovakia, Austria, the United States, and the United Kingdom. It argues that biomedical research on TBE was profoundly intertwined with political and military agendas and depended on civil...
Source: Medical History - September 8, 2023 Category: History of Medicine Authors: Anna Mazanik Source Type: research