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Combining Watchman left atrial appendage closure and catheter ablation for atrial fibrillation: multicentre registry results of feasibility and safety during implant and 30 days follow-up
ConclusionThe outcomes from these international, multicentre registries support the feasibility and safety of performing combined procedures of ablation and Watchman LAAC for patients with non-valvular AF and high stroke risk. Further data are needed on long-term outcomes for the hybrid technique on all-cause stroke and mortality.
Source: Europace - July 3, 2017 Category: Cardiology Source Type: research

Harnessing the Four Elements for Mental Health
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is pre...
Source: Frontiers in Psychiatry - April 23, 2019 Category: Psychiatry Source Type: research

Umbilical Cord Blood Mononuclear Cells for Ex-Vivo Gene Therapy
This study was supported by the grant of Russian Science Foundation No 16-15-00010. Kazan Federal University was supported by the Russian Government Program of Competitive Growth.DisclosuresNo relevant conflicts of interest to declare.
Source: Blood - November 21, 2018 Category: Hematology Authors: Bashirov, F. V., Salafutdinov, I. I., Sokolov, M. E., Izmailov, A. A., Markosyan, V. A., Fadeev, F. O., Rizvanov, A., Islamov, R. I. Tags: 801. Gene Therapy and Transfer Source Type: research

The Prevalence and Clinical Features of Fabry Disease in Hemodialysis Patients: Russian Nationwide Fabry Dialysis Screening Program
Conclusions: Screening in at-risk patients remains the feasible approach to diagnose Fabry disease in patients with ESRD and their family members, given a low awareness of Fabry disease among the Russian nephrologists.Nephron
Source: Nephron - January 27, 2019 Category: Urology & Nephrology Source Type: research

Low- and moderate-dose non-cancer effects of ionizing radiation in directly exposed individuals, especially circulatory and ocular diseases: a review of the epidemiology.
CONCLUSIONS: We document statistically significant excess risk of the major types of circulatory disease, specifically ischemic heart disease and stroke, in moderate- or low-dose exposed groups, with some not altogether consistent evidence suggesting dose response non-linearity, particularly for stroke. However, the patterns of risk reported are not straightforward. We also document evidence of excess risks at lower doses/dose-rates of posterior subcapsular and cortical cataract in the Chernobyl liquidators, US Radiologic Technologists and Russian Mayak nuclear workers, with fundamentally linear dose response. Nuclear cata...
Source: International Journal of Radiation Biology - January 22, 2021 Category: Radiology Tags: Int J Radiat Biol Source Type: research

Cutaneomeningospinal Angiomatosis (Cobb Syndrome) in a Young Patient.
Abstract Cobb Syndrome (Spinal Arteriovenous Metameric Syndrome 1-31 (SAMS 1-31)) is a rare, non-hereditary disorder. Approximately 100 cases of CS have been described to date. The actual incidence may be much higher since only symptomatic patients were documented. In particular, post mortem studies suggest a possibly higher incidence of this syndrome. The main clinical manifestations of this syndrome include skin stains of vascular nature on the torso, in combination with spinal vascular malformations localized in one and the same metameric or spinal segment. A rare diagnosis of this syndrome in patients over 18 ...
Source: CNS and Neurological Disorders Drug Targets - February 17, 2021 Category: Drugs & Pharmacology Authors: Putilina M, Teplova N, Dvornikov A Tags: CNS Neurol Disord Drug Targets Source Type: research

Cutaneomeningospinal Angiomatosis (Cobb Syndrome) in a Young Patient
CNS Neurol Disord Drug Targets. 2021 Feb 17. doi: 10.2174/1871527320666210218083550. Online ahead of print.ABSTRACTCobb Syndrome (Spinal Arteriovenous Metameric Syndrome 1-31 (SAMS 1-31)) is a rare, non-hereditary disorder. Approximately 100 cases of CS have been described to date. The actual incidence may be much higher since only symptomatic patients were documented. In particular, post mortem studies suggest a possibly higher incidence of this syndrome. The main clinical manifestations of this syndrome include skin stains of vascular nature on the torso, in combination with spinal vascular malformations localized in one...
Source: CNS and Neurological Disorders Drug Targets - February 19, 2021 Category: Drugs & Pharmacology Authors: Marina Putilina Nataliya Teplova Anton Dvornikov Source Type: research

Exploring age-sex-specific all-cause mortality in Russia using the RLMS-HSE cohort study data
ConclusionsDeath numbers because of stroke are around the same among males and females. Deaths due to cardiac and neoplasms prevailed in males. Fatal cases due to injuries/accidents among males were more than twice that among females, same for murder/self-murders. The mean death age for cause-related to neoplasm, cardiac, and stroke was around as general population - 66, 69, and 72 years old, and was more than 80 years in senility/old age cause.Key messagesThe official statistics of mortality by Federal State Statistics Service and results getting from surveys are compatible with each other, therefore adequately reflecting...
Source: The European Journal of Public Health - October 20, 2021 Category: General Medicine Source Type: research

Language abilities, not cognitive control, predict language mixing behavior in bilingual speakers with aphasia
CONCLUSIONS: Linguistic factors such as pre- and post-stroke self-rated language proficiency and level of language impairment due to aphasia were found to predict LM frequency in L1-Russian and in L2-Hebrew. Cognitive abilities did not predict LM frequency. Based on our findings, we suggest that LM behavior in BiPWAs might be primarily related to language skills in L1 and L2, rather than to cognitive control impairments.PMID:37579674 | DOI:10.1016/j.jcomdis.2023.106367
Source: Journal of Communication Disorders - August 14, 2023 Category: Speech-Language Pathology Authors: Alina Bihovsky Michal Ben-Shachar Natalia Meir Source Type: research

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