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Specialty: Neurology
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Total 133 results found since Jan 2013.

Stroke and digital technology: a wake-up call from COVID-19 pandemic
ConclusionThe global emergency represented by the COVID-19 pandemic can be the stimulus to accelerate the digitalization process in the field of stroke for the use of new methods on a large scale.
Source: Neurological Sciences - January 12, 2021 Category: Neurology Source Type: research

Impact of SARS-CoV-2 on reperfusion therapies for acute ischemic stroke in Lombardy, Italy: the STROKOVID network
AbstractWhether and how SARS-CoV-2 outbreak affected in-hospital acute stroke care system is still matter of debate. In the setting of the STROKOVID network, a collaborative project between the ten centers designed as hubs for the treatment of acute stroke during SARS-CoV-2 outbreak in Lombardy, Italy, we retrospectively compared clinical features and process measures of patients with confirmed infection (COVID-19) and non-infected patients (non-COVID-19) who underwent reperfusion therapies for acute ischemic stroke. Between March 8 and April 30, 2020, 296 consecutive patients [median age, 74 years (interquartile range (IQ...
Source: Journal of Neurology - March 8, 2021 Category: Neurology Source Type: research

SARS-CoV-2 infection and acute ischemic stroke in Lombardy, Italy
ConclusionsIschemic strokes in COVID-19 patients have distinctive risk factor profile and etiology, increased clinical severity and higher in-hospital mortality rate compared to non-COVID-19 patients. A simple model based on clinical and routine laboratory parameters may be useful in identifying ischemic stroke patients with SARS-CoV-2 infection who are unlikely to survive the acute phase.
Source: Journal of Neurology - May 24, 2021 Category: Neurology Source Type: research

Regional Differences in Early BP Management After Acute Ischemic Stroke in the ENCHANTED International Randomized Controlled Trials
Conclusion: Regional variations in early BP management in acute stroke translated into differences in early BP control parameters.
Source: Frontiers in Neurology - August 27, 2021 Category: Neurology Source Type: research

Mechanical thrombectomy in acute ischemic stroke due to large vessel occlusion in the anterior circulation and low baseline National Institute of Health Stroke Scale score: a multicenter retrospective matched analysis
ConclusionsOur experience is in favor of a potential benefit of MT also in patients with LVO and a NIHSS score  ≤ 5 at the time of groin puncture. Nonetheless, this issue waits for a clear-cut recommendation in a dedicated clinical trial.
Source: Neurological Sciences - November 29, 2021 Category: Neurology Source Type: research

Italian translation and cross-cultural validation of an assessment tool for participation in stroke survivors: the Frenchay Activities Index
ConclusionFAI-I provides a tool for professionals to measure participation in Italian stroke patients in health and social care settings.
Source: Neurological Sciences - February 18, 2022 Category: Neurology Source Type: research

Brivaracetam as add-on treatment in patients with post-stroke epilepsy: real-world data from the BRIVAracetam add-on First Italian netwoRk Study (BRIVAFIRST)
Stroke is a leading disease worldwide, with an estimated incidence of more than 15 million cases annually [1]. Post-stroke epilepsy (PSE), which is defined as the occurrence of one or more unprovoked epileptic seizures at least one week after the stroke, develops in at least 4-6% of the stroke population [2]. Cerebrovascular disease is one of the most common causes of acquired epilepsy and accounts for about 10-15% of all newly diagnosed epilepsy cases [2]. Although PSE has overall a good prognosis and patients are generally responsive to pharmacological treatment, approximately 20% of the patients are pharmaco-resistant [3,4].
Source: Seizure: European Journal of Epilepsy - March 10, 2022 Category: Neurology Authors: Simona Lattanzi, Laura Canafoglia, Maria Paola Canevini, Sara Casciato, Emanuele Cerulli Irelli, Valentina Chiesa, Filippo Dainese, Giovanni De Maria, Giuseppe Didato, Giancarlo Di Gennaro, Giovanni Falcicchio, Martina Fanella, Edoardo Ferlazzo, Massimo G Source Type: research

Bringing door-to-needle times within the European benchmarks results in better  stroke patients outcomes in a spoke hospital from the Apulian Region
AbstractIntroductionDoor-to-needle time (DNT) is a key factor in acute stroke treatment success. We retrospectively analysed the effects of a new protocol aimed at reducing treatment delays in our single-centre observational series over a 1-year period (from October 1st 2021 to September 30th 2022).MethodsThe time frame was divided into two semesters as a new protocol was started at the beginning of the second semester to ensure a rapid evaluation, imaging, and intravenous thrombolysis in all stroke patients attending our spoke-hospital serving 200,000 inhabitants. Logistics and outcome measures were obtained for each pati...
Source: Neurological Sciences - May 6, 2023 Category: Neurology Source Type: research

Incidence of orolingual angioedema after intravenous thrombolysis for stroke
DiscussionThe incidence of orolingual angioedema was very low in our series. Although OA is usually mild, anaphylactoid reactions may rarely occur, because of the variable degree of activation of the complement system and kinin cascade caused by alteplase. In such instances, admission to neurointensive care may be required. Specific bradykinin antagonists or drugs that target the kallikrein-kinin system are beginning to be used in the more severe cases. Thus, doctors and nurses caring for acute stroke patients need to be able to recognize and treat this complication.
Source: Neurological Sciences - August 6, 2018 Category: Neurology Source Type: research

Stroke-Like Presentation of Paraneoplastic Cerebellar Degeneration: a Single-Center Experience and Review of the Literature
We report herein incidence and clinical features of hyperacute onset PCD, a vertebrobasilar stroke mimic. We performed a retrospective analysis of all suspected PCD cases referred to the Udine University Hospital between 2009 and 2017. Our center provides the only neuroimmunology laboratory for three provinces of the Friuli-Venezia Giulia region, Italy (983,190 people as of January 1, 2017). Inclusion criteria were (1) abrupt onset of neurological symptoms; (2) initial consideration of a vascular etiology; (3) final diagnosis of “definite PCD.” We also carried out a systematic review of the literature in order to ident...
Source: The Cerebellum - August 28, 2019 Category: Neurology Source Type: research

The inter-rater reliability of the Italian version of Aphasia Rapid Test (ART) for acute ischemic stroke
ConclusionsThis study showed that the cross-cultural adaptation of the French version of the ART was successful in an Italian-speaking population.
Source: Neurological Sciences - September 14, 2019 Category: Neurology Source Type: research

Failure of Therapeutic Anticoagulation in COVID-19 Patients With Acute Ischemic Stroke. A Retrospective Multicenter Study
ConclusionsThe occurrence of an anticoagulation failure seems to be increased in the setting of COVID-19 infection, with worse clinical outcomes if compared to non-COVID-19 related ischemic strokes. We discuss the diagnostic and therapeutic implications of such evidence, suggesting that some arterial thrombotic complications might be either resistant to or independent of the anticoagulation effect.
Source: Frontiers in Neurology - March 4, 2022 Category: Neurology Source Type: research

Carotid artery stenting during endovascular thrombectomy for acute ischemic stroke with tandem occlusion: the Italian Registry of Endovascular Treatment in Acute Stroke
ConclusionsAmong AIS patients with TO, CAS during EVT was associated with a higher rate of successful reperfusion and a lower rate of 3  months’ mortality.
Source: Acta Neurologica Belgica - September 2, 2022 Category: Neurology Source Type: research

Acute stroke care in France: Survey in the 138 stroke units
CONCLUSION: There are still avenues for improvement in acute stroke care in France, especially concerning the number and regional repartition of I-SU beds, and access to reperfusion therapies.PMID:36336492 | DOI:10.1016/j.neurol.2022.07.010
Source: Revue Neurologique - November 6, 2022 Category: Neurology Authors: D Leys A Falcou J-L Mas Source Type: research