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Total 456 results found since Jan 2013.
Adult-onset leukodystrophy with vanishing white matter: a case series of 19 patients
ConclusionsAO-LVWM presents varying clinical manifestations at onset, including stroke-like events. WM rarefaction is the most consistent diagnostic clue even in the latest onset cases. Spectroscopy and electrophysiological features are compatible with axon, rather than myelin, damage. Cerebral glucose metabolic abnormalities and retinal alterations can be present. LVWM might also be caused by a digenic inheritance affecting the eIF2B complex.
Source: Journal of Neurology - May 12, 2023 Category: Neurology Source Type: research
Overview of the role of robots in upper limb disabilities rehabilitation: a scoping review
ConclusionsOur findings show that robots can improve musculoskeletal functions (musculoskeletal strength, sensation, perception, vibration, muscle coordination, less spasticity, flexibility, and range of motion) and empower people by providing a variety of rehabilitation capabilities.
Source: Archives of Public Health - May 8, 2023 Category: International Medicine & Public Health Source Type: research
Late-onset fabry disease due to the p.Phe113Leu variant: the first italian cluster of five families
ConclusionThis study demonstrates that a cluster of subjects with p.Phe113Leu pathogenic variant is also present in Southern Italy. Disease manifestations are frequent in both sexes and may occur early in life. Cardiac involvement represents the core manifestation, but neurological and renal involvement is also frequent, suggesting that extra-cardiac complications deserve clinical attention.
Source: Metabolic Brain Disease - April 25, 2023 Category: Neurology Source Type: research
IJERPH, Vol. 20, Pages 5224: Assessing the Social and Environmental Impact of Healthcare Technologies: Towards an Extended Social Return on Investment
This study provides a model for combining economic, social and environmental outcomes that, besides contributing to theory, could be useful for decision-making.
Source: International Journal of Environmental Research and Public Health - March 22, 2023 Category: Environmental Health Authors: Maria Pinelli Stefania Manetti Emanuele Lettieri Tags: Article Source Type: research
The effect of robot-assisted walking in different modalities on cardiorespiratory responses and energy consumption in patients with subacute stroke
DISCUSSION: By decreasing GF and BWS values during robot-assisted walking, adequate cardio-metabolic and energy response in both subacute stroke patients and healthy individuals could be achieved. These results show us that it is important to consider the cardiorespiratory function of the patient when choosing training protocols.PMID:36884354 | DOI:10.1080/01616412.2023.2188520
Source: Neurological Research - March 8, 2023 Category: Neurology Authors: Ahmet Mert Say ın Neslihan Duruturk Birol Balaban S üleyman Korkusuz Source Type: research
Your native tongue holds a special place in your brain, even if you speak 10 languages
This study “contributes to our understanding of how our brain learns new things,” says Augusto Buchweitz, a cognitive neuroscientist at the University of Connecticut, Storrs, who was not involved in the work. “The earlier you learn something, the more your brain [adapts] and probably uses less resources.”
Scientists have largely ignored what’s going on inside the brains of polyglots—people who speak more than five languages—says Ev Fedorenko, a cognitive neuroscientist at the Massachusetts Institute of Technology who led the new study. “There’s oodles of work on individuals whose language systems are...
Source: Science of Aging Knowledge Environment - February 3, 2023 Category: Geriatrics Source Type: research
Correlates of participation six months after stroke in an Italian population: results from the RIPS (Post-Stroke Intensive Rehabilitation) Study
CONCLUSIONS: In our cohort of patients addressing postacute stroke rehabilitation, prestroke participation levels were on average good, while they were severely reduced six months after stroke for all the considered items except reading and making trips. Higher FAI at follow-up was independently associated with a higher functional level and no cognitive impairment at follow-up, with lower stroke severity in the postacute phase, as well as a higher anamnestic participation score.CLINICAL REHABILITATION IMPACT: Our results suggest that investigating prestroke participation may be highly relevant to predict, and possibly addr...
Source: European Journal of Physical and Rehabilitation Medicine - February 1, 2023 Category: Rehabilitation Authors: Chiara Castagnoli Silvia Pancani Teresa Barretta Leonardo Pellicciari Silvia Campagnini Benedetta Basagni Camilla Gucci Alessandro Sodero Erika Guolo Bahia Hakiki Antonello Grippo Andrea Mannini Claudio Macchi Francesca Cecchi Source Type: research
Unlucky numbers: Fighting murder convictions that rest on shoddy stats
LEIDEN, THE NETHERLANDS—
When a Dutch nurse named Lucia de Berk stood trial for serial murder in 2003, statistician Richard Gill was aware of the case. But he saw no reason to stick his nose into it.
De Berk was a pediatric nurse at Juliana Children’s Hospital in The Hague. In 2001, after a baby died while she was on duty, a colleague told superiors that De Berk had been present at a suspiciously high number of deaths and resuscitations. Hospital staff immediately informed the police. When investigators reexamined records from De Berk’s shifts, they found 10 suspicious incidents. Three other hospitals where D...
Source: Science of Aging Knowledge Environment - January 19, 2023 Category: Geriatrics Source Type: research
The impact of COVID-19 on myocardial infarctions, strokes and out-of-hospital cardiopulmonary arrests: an observational retrospective study on time-sensitive disorders in the Friuli Venezia Giulia region (Italy)
AbstractThe COVID-19 global pandemic has changed considerably the way time-sensitive disorders are treated. Home isolation, people ’s fear of contracting the virus and hospital reorganisation have led to a significant decrease in contacts between citizens and the healthcare system, with an expected decrease in calls to the Emergency Medical Services (EMS) of the Friuli-Venezia Giulia (FVG) region. However, mortality in clinic al emergencies like acute ST-elevation myocardial infarction (STEMI), stroke and out-of-hospital cardiopulmonary arrest (OHCA) remained high. An observational retrospective cross-sectional study was...
Source: International Journal of Emergency Medicine - December 29, 2022 Category: Emergency Medicine Source Type: research
IJERPH, Vol. 19, Pages 16741: 1000 Days: The & ldquo;WeCare Generation & rdquo; Program & mdash;The Ultimate Model for Improving Human Mental Health and Economics: The Study Protocol
Discussion: An overall rate of return on investment (ROI) statistically significant 13.0% per annum with an associated benefit/cost ratio (BCR) of 6.3 is expected as the primary outcome of the “WeCare Generation” program. Our proposed model predicts a new medical paradigm aiming to empower new generations, with a strong return on economy and health.
Source: International Journal of Environmental Research and Public Health - December 13, 2022 Category: Environmental Health Authors: Orlando Uccellini Andrea Benlodi Emanuele Caroppo Loredana Cena Gianluca Esposito Isabel Fernandez Maria Ghazanfar Antonio Imbasciati Francesco Longo Marianna Mazza Giuseppe Marano Renata Nacinovich Antonio Pignatto Arthur Rolnick Marco Trivelli Elena Spa Tags: Article Source Type: research
How the work of respiratory physiotherapists changes the tracheostomy management and decannulation in a NICU department: an Italian experience
We described the number of decannulations, the length of stay in NICU and decannulation time; the diagnosis of decannulated patients and the number of deaths. 928 total patients were analysed: 468 in P1, 460 in P2. Total length of stay or number of deaths did not change significantly between the two periods, while the number of decannulated patients before the discharge was higher in P2 143 (64%), compared with P1 79 (36%) p<0.001. More patients with neurological pathologies involving possible swallowing disorders, such as cerebral haemorrhage, head trauma and stroke, have been successfully decannulated in P2 than in P1...
Source: Monaldi Archives for Chest Disease - November 25, 2022 Category: Respiratory Medicine Authors: Davide Papi Giulia Montigiani Luca Bucciardini Source Type: research
