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Total 105 results found since Jan 2013.
Relationship between antibiotic resistance with class 1 integron and SmeDEF efflux pump encoding genes in clinical isolates of Stenotrophomonas maltophilia
J Appl Genet. 2023 Aug 14. doi: 10.1007/s13353-023-00776-6. Online ahead of print.ABSTRACTStenotrophomonas maltophilia is an emerging multidrug-resistant organism with an increasing frequency of hospital-acquired infections predominantly in developing countries. The purpose of this study was to determine the antibiotic resistance and frequency of the smeD, class 1 integron, and sul1 genes in clinical isolates of S. maltophilia in two Iranian provinces. From January 2020 to September 2021, 38 clinical isolates of S. maltophilia were collected from patients in hospitals in Tabriz and Sanandaj provinces of Iran. S. maltophili...
Source: J Appl Genet - August 13, 2023 Category: Genetics & Stem Cells Authors: Soheila Bafandeh Zamanpour Rasoul Yousefi Mashouf Himen Salimizand Mohsen Nazari Mohammad Yousef Alikhani Safar Farajnia Source Type: research
The increasing antimicrobial resistance of < em > Shigella < /em > species among Iranian pediatrics: a systematic review and meta-analysis
CONCLUSION: Our findings revealed that ciprofloxacin is an effective drug for shigellosis in Iranian children. The substantially high prevalence estimation proposes that the first- and second-line treatments for shigellosis are the major threat to public health and active antibiotic treatment policies are essential.PMID:36794800 | DOI:10.1080/20477724.2023.2179451
Source: Pathogens and Global Health - February 16, 2023 Category: International Medicine & Public Health Authors: Amirhossein Baharvand Leila Molaeipour Sogol Alesaeidi Reyhane Shaddel Noushin Mashatan Taghi Amiriani Melika Kiaei Sudkolaei Sara Abbasian Bashar Zuhair Talib Al-Naqeeb Ebrahim Kouhsari Source Type: research
Distribution of Virulence Genes in < em > Campylobacter < /em > spp. Isolated from < em > Agaricus < /em > Mushrooms in Iran
In this study, 740 Agaricus mushroom samples were gathered randomly from various markets from June 2020 to December 2020. Confirmation of Campylobacter spp. using biochemical analyses and 23S rRNA-based PCR was performed. The agar dilution technique was used to determine resistance to antibiotics using gentamicin (GM10μg), ciprofloxacin (CIP5μg), nalidixic acid (NA30μg), tetracycline (TE30μg), ampicillin (AM10μg), amoxicillin+ clavulanic acid (AMC30μg), erythromycine (E15μg), azithromycin (AZM15μg), clindamycin (CC2μg), and chloramphenicol (C30μg). Multiplex PCR was utilized to determine the prevalence of the rec...
Source: Biomed Res - February 10, 2023 Category: Research Authors: Maryam Sadat Emami Amir Shakerian Reza Sherafati Chaleshtori Ebrahim Rahimi Source Type: research
< em > In Silico < /em > Design and In Vitro Evaluation of Some Novel AMPs Derived From Human LL-37 as Potential Antimicrobial Agents for Keratitis
In this study, a novel decapeptide (Catoid) and its dimer (Dicatoid) based on human cathelicidin (LL-37) have been designed by bioinformatics tools to be used in the treatment of bacterial keratitis. After the selection and synthesis of peptide sequences, their antimicrobial activities against the standard and resistant strains of Pseudomonas aeruginosa and Staphylococcus aureus were evaluated. This test was performed with LL-37, gentamicin, ciprofloxacin, amikacin, and penicillin for a more accurate comparison. Furthermore, the cytotoxicity levels of the specified compounds on fibroblast cells and bovine corneal endotheli...
Source: Cell Research - January 30, 2023 Category: Cytology Authors: Arsalan Pashapour Soroush Sardari Parastoo Ehsani Source Type: research
Role of MexAB-OprM efflux pump in the emergence of multidrug-resistant clinical isolates of Pseudomonas aeruginosa in Mazandaran province of Iran
CONCLUSION: We found that increasing the expression of the mexB gene can cause the emergence of multidrug-resistant strains by increasing the minimum inhibitory concentration of the antibiotics. Then, we need to evaluate the resistance mechanisms separately in different area of a country to improve the antibiotic stewardship.PMID:36626068 | DOI:10.1007/s11033-022-08230-2
Source: Molecular Biology Reports - January 10, 2023 Category: Molecular Biology Authors: Leila Ahmadian Mohammad Reza Haghshenas Bahman Mirzaei Younes Khalili Hamid Reza Goli Source Type: research
Prevalence and distribution of antimicrobial resistance in effluent wastewater from animal slaughter facilities: A systematic review
Environ Pollut. 2022 Dec 20:120848. doi: 10.1016/j.envpol.2022.120848. Online ahead of print.ABSTRACTThe extensive use of antibiotics in food animal production and disposal of untreated wastewater from food animal slaughter facilities may create a shift in microbiomes of different ecosystems by generating reservoirs of antimicrobial resistance along the human-animal-environmental interface. This epidemiological problem has been studied, but its magnitude and impact on a global scale is poorly characterised. A systematic review was done to determine global prevalence and distribution patterns of antimicrobial resistance in ...
Source: Environmental Pollution - December 23, 2022 Category: Environmental Health Authors: Leo Foyle Matthew Burnett Abbey Creaser Rachel Hens Julia Keough Lauren Madin Ruby Price Hayley Smith Samuel Stone Robert T Kinobe Source Type: research
Antimicrobial resistance patterns and virulence gene profiles of Salmonella enteritidis and Salmonella typhimurium recovered from patients with gastroenteritis in three cities of Iran
This study evaluated distribution of virulence factors and antibiotic resistance in clinical isolates of Salmonella enteritidis and Salmonella typhimurium in three cities of Iran. Altogether 48 S. enteritidis and S. typhimurium isolates were collected from patients at certain Iranian hospitals between May 2018 and September 2021. Antimicrobial susceptibility testing was performed by disk diffusion and broth microdilution methods. The presence of antibiotic-resistance genes (bla TEM, bla SHV, bla CTX-M, bla NDM, strA, strB, aadA1, tetA, tetB, floR, sul1, sul2, dfrA), integrons (classe 1 and 2), and virulence-associated gene...
Source: Acta Microbiologica et Immunologica Hungarica - November 12, 2022 Category: Microbiology Authors: Javad Yasbolaghi Sharahi Ali Hashemi Seyyed Mohammad Javad Mousavi Abazar Pournajaf Soheila Moradi Bidhendi Source Type: research
