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Drug: Melatonin
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Total 16 results found since Jan 2013.
Photoperiodic modulation of melatonin receptor and immune genes in migratory redheaded bunting
Comp Biochem Physiol A Mol Integr Physiol. 2023 Jan 29:111381. doi: 10.1016/j.cbpa.2023.111381. Online ahead of print.ABSTRACTThe transcriptional regulation of innate immune function across annual life history states (LHS) remains obscure in avian migrants. We, therefore, investigated this in a migratory passerine songbird, redheaded bunting (Emberiza bruniceps), which exhibits long-distance vernal migration from India to Central Asia. We exposed the birds (N = 10) to differential photoperiodic conditions to induce a non-migratory (NM), pre-migratory (PM), migratory (MIG), and refractory (REF) state, and performed gene exp...
Source: Comparative Biochemistry and Physiology. Part A, Molecular and integrative physiology. - February 1, 2023 Category: Physiology Authors: Jyoti Tiwari Sayantan Sur Asma Naseem Sangeeta Rani Shalie Malik Source Type: research
Night melatonin levels affect cognition in diurnal animals: Molecular insights from a corvid exposed to an illuminated night environment
This study investigated the role of nocturnal melatonin secretion in the cognitive performance of diurnal animals. An initial experiment measured the cognitive performance in Indian house crows treated for 11 days with 12 h light at 1.426 W/m2 (∼150 lux) coupled with 12 h of 0.058 W/m2 (∼6-lux) dim light at night (dLAN) or with absolute darkness (0 lux dark night, LD). dLAN treatment significantly decreased midnight melatonin levels and negatively impacted cognitive performance. Subsequently, the role of exogenous melatonin (50 μg; administered intraperitoneally half an hour before the night began) was assessed on the...
Source: Environmental Pollution - June 17, 2022 Category: Environmental Health Authors: Amaan Buniyaadi Abhilash Prabhat Sanjay Kumar Bhardwaj Vinod Kumar Source Type: research
Dopamine Gene Polymorphism, Biochemical and Oxidative Stress Parameters in Geriatric Population with and Without Depression: A Pilot Study
Indian J Clin Biochem. 2022 Jan;37(1):69-76. doi: 10.1007/s12291-020-00928-z. Epub 2021 Jan 3.ABSTRACTDopamine transporter takes released dopamine back into presynaptic terminals and has been implicated in several aging disorders including depression. The present study was designed to demonstrate dopamine gene polymorphism, its circulatory levels, biochemical and oxidative stress parameters in geriatric population with and without depression. Thirty geriatric patients with depression and thirty age and sex matched normal controls were genotyped for Dopamine Active Transporter (DAT TaqA1 and DAT VNTR) gene polymorphisms usi...
Source: Clinical Biochemistry - February 7, 2022 Category: Biochemistry Authors: Raza Abbas Mahdi Israr Ahmad Talha Jilani Jamal Akhtar Ansari Farzana Mahdi Abbas Ali Mahdi Tabrez Jafar Source Type: research
Stress associated ovarian dysfunctions in a seasonal breeder, Funambulus pennanti: Role of glucocorticoids and possible amelioration by melatonin
Gen Comp Endocrinol. 2021 Dec 7:113962. doi: 10.1016/j.ygcen.2021.113962. Online ahead of print.ABSTRACTStudies have shown that stress caused by lack of physical activity disrupts the normal pattern of glucocorticoid secretion which adversely affects the reproductive axis. We studied the effect of chronic movement restriction on ovarian responses in the Indian Palm Squirrel Funambulus pennanti, a highly active diurnal rodent. Physical restraint of squirrels induced stress that led to a significant increase in plasma cortisol, corticosterone and decreased 17β-estradiol level leading to follicular atresia. Ovarian Reactive ...
Source: General and Comparative Endocrinology - December 10, 2021 Category: Endocrinology Authors: Jayita Pal Chowdhury Chandana Haldar Source Type: research
A Randomized Controlled Trial of High Rate rTMS Versus rTMS and Amitriptyline in Chronic Migraine
CONCLUSION: Combination of rTMS and amitriptyline is safe and more effective in CM compared to rTMS alone.PMID:34554691
Source: Pain Physician - September 23, 2021 Category: Anesthesiology Authors: Jayantee Kalita Sumit Kumar Varun K Singh Usha K Misra Source Type: research
Gonadotropin inhibitory hormone receptors (GnIHRs): Molecular characterization and synergistic effect of different drugs in Indian major carp, Labeo catla
Gen Comp Endocrinol. 2021 Sep 13:113904. doi: 10.1016/j.ygcen.2021.113904. Online ahead of print.ABSTRACTAfter the discovery of Gonadotropin-inhibitory hormone (GnIH) in birds in 2000, it showed different roles in different vertebrate classes and even in different species of same classes. In birds and mammals, GnIH inhibits the expression of gonadotropins during reproduction, while in fishes it exerts both inhibitory and stimulatory effect on reproduction. The current study evaluates the role of GnIH during reproduction in Labeo catla. The partial cDNA sequence of GnIHR1 and GnIHR3 receptor genes was identified by degenera...
Source: General and Comparative Endocrinology - September 16, 2021 Category: Endocrinology Authors: Pravesh Kumar None K S Wisdom Roshan Kumar Ram Pathakota Gireesh-Babu Sunil Kumar Nayak None N S Nagpure Rupam Sharma Source Type: research
Melatonin contributes to the hypertrophic differentiation of mesenchymal stem cell-derived chondrocytes via activation of the Wnt/beta-catenin signaling pathway : Melatonin promotes MSC-derived chondrocytes hypertrophy
CONCLUSIONS: The current findings demonstrate that melatonin enhances the hypertrophic differentiation of MSC-derived chondrocytes through the Wnt signaling pathway. Our findings add evidence to the role of melatonin in promoting bone development and highlight the positive effects of melatonin on terminal differentiation of chondrocytes.PMID:34419165 | DOI:10.1186/s13287-021-02536-x
Source: Cell Research - August 22, 2021 Category: Cytology Authors: Xuan Wang Tianwei He Lei He Bu Yang Zhongyu Liu Mao Pang Peigen Xie Liangming Zhang Limin Rong Source Type: research
Myopia, Melatonin and Conjunctival Ultraviolet Autofluorescence: A Comparative Cross-sectional Study in Indian Myopes
CONCLUSION: This study demonstrates an inverse relationship between serum melatonin levels and degree of CUVAF in myopes. A novel link between serum melatonin, axial length and outdoor sun exposure is highlighted in the current study.PMID:33646852 | DOI:10.1080/02713683.2021.1894580
Source: Current Eye Research - March 1, 2021 Category: Opthalmology Authors: Saumya Kumar Noopur Gupta Thirumurthy Velpandian Vivek Gupta M Vanathi Praveen Vashist L Gowtham Rohit Saxena Radhika Tandon Source Type: research
