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Drug: Taxotere
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Total 54 results found since Jan 2013.
Nanoencapsulation of Docetaxel Induces Concurrent Apoptosis and Necroptosis in Human Oral Cancer Cells (SCC-9) via TNF- α/RIP1/RIP3 Pathway
Indian J Clin Biochem. 2023 Jul;38(3):351-360. doi: 10.1007/s12291-022-01055-7. Epub 2022 Aug 9.ABSTRACTHuman oral squamous cell carcinoma is the sixth most frequent malignant cancer, with an unacceptably high death rate that affects people's health. Albeit, there are several clinical approaches for diagnosing and treating oral cancer they are still far from ideal. We previously synthesised and characterised the docetaxel nanoformulation (PLGA-Dtx) and discovered that docetaxel nanoencapsulation may suppress oral cancer cells. The goal of this study was to figure out the mechanism involved in the suppression of oral cancer...
Source: Clinical Biochemistry - May 26, 2023 Category: Biochemistry Authors: Parul Gupta Arpita Singh Ajay Kumar Verma Surya Kant Anuj Kumar Pandey Anupam Mishra Puneet Khare Ved Prakash Source Type: research
Polymorphisms in solute carrier genes (SLC19A1, SLCO1B1, and SLCO1B3) predicts survival and toxicity in North Indian lung cancer patients undergoing platinum-based doublet chemotherapy
CONCLUSION: Our findings imply that Solute Carrier gene polymorphisms modulate the overall survival in lung cancer patients undergoing platin-based doublet chemotherapy, also these polymorphisms have a modifying impact on the associated adverse events/toxicity.PMID:35896189 | DOI:10.1111/jcpt.13748
Source: Clinical Lung Cancer - July 27, 2022 Category: Cancer & Oncology Authors: Parul Sharma Navneet Singh Siddharth Sharma Source Type: research
Structural, functional analysis and association of MSH6 rs1800932, rs1042821 polymorphisms with clinical outcome in North Indian lung cancer patients treated with platinum-based doublet chemotherapy
CONCLUSIONS: These results suggest that MSH6 rs1800932 rs1042821 polymorphisms are involved in increasing the overall survival of lung cancer patients, further confirmed by computational analysis.PMID:35868444 | DOI:10.1016/j.amjms.2022.07.005
Source: The American Journal of the Medical Sciences - July 22, 2022 Category: General Medicine Authors: Sidhartha Singh Navneet Singh Manoj Baranwal Siddharth Sharma Source Type: research
Combination therapy in metastatic castration sensitive prostate cancer: A Systematic review and network meta-analysis
Conclusion: Overall, abiraterone demonstrated better OS and FFS outcomes as compared to all the other combination strategies in this NMA.
Source: Indian Journal of Urology - July 1, 2022 Category: Urology & Nephrology Authors: Jatinder Kumar Muhammad Umar Alam Seyed Behzad Jazayeri Karthik Tanneru Soroush Bazargani Charu Shastri Shiva Gautam Shahriar Koochekpour Sanjeev Shukla Mark Bandyk Joseph Costa KC Balaji Source Type: research
< sup > 177 < /sup > Lu-PSMA-617 versus docetaxel in chemotherapy-na ïve metastatic castration-resistant prostate cancer: a randomized, controlled, phase 2 non-inferiority trial
CONCLUSION: 177Lu-PSMA-617 was demonstrated to be safe and non-inferior to docetaxel in the treatment of mCRPC and could, thus, be potentially employed earlier in the disease course rather than being solely reserved for advanced end-stage disease.CLINICAL TRIAL REGISTRATION: Clinical Trials Registry-India, CTRI/2019/12/022282.PMID:34842950 | DOI:10.1007/s00259-021-05618-3
Source: Molecular Medicine - November 29, 2021 Category: Molecular Biology Authors: Swayamjeet Satapathy Bhagwant Rai Mittal Ashwani Sood Chandan Krushna Das Ravimohan Suryanarayan Mavuduru Shikha Goyal Jaya Shukla Shrawan Kumar Singh Source Type: research
Clinico-epidemiological profile and treatment outcomes in patients with squamous cell carcinoma of the esophagus following docetaxel-based neoadjuvant chemotherapy: experience from a cancer care center in Northeast India
CONCLUSIONS: Preoperative chemotherapy with a taxane-based triple-drug regimen is a reasonable approach in squamous cell carcinoma of the esophagus, associated with improvement in complete pathological response rates, increases complete resection rates, with manageable toxicity.PMID:34674048 | DOI:10.1186/s43046-021-00094-0
Source: J Egypt Natl Canc In... - October 21, 2021 Category: Cancer & Oncology Authors: Partha Sarathi Roy Gaurav Kumar Sreya Mallik Satya Sadhan Sarangi Bhargab Jyoti Saikia Munlima Hazarika Abhijit Talukdar Source Type: research
Histiocytic and follicular dendritic cell sarcoma: Diagnostically challenging rare entities
CONCLUSION: FDCS and HS are under-recognized and easily prone to a wrong diagnosis. Therefore, considering these rare entities in differential diagnoses and inclusion of proper IHC biomarkers are necessary to avoid potential misdiagnosis.PMID:33851626 | DOI:10.4103/IJPM.IJPM_461_20
Source: Indian Journal of Pathology and Microbiology - April 14, 2021 Category: Pathology Authors: Sanjiban Patra Priti Trivedi Kanwalpreet Kaur Source Type: research
