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Vaccination: Malaria Vaccine
Countries: Ghana Health

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Total 28 results found since Jan 2013.

HBV Infection Is an Intermediate-Risk Disease, Whereas Anaemia Is a Mild-to-Moderate Public Health Problem in Young Ghanaian Adults: A Four-Year Retrospective Analysis of Students' Medical Records
CONCLUSION: Intentional preventative public health campaigns regarding anaemia, HBV, and HCV infection should, respectively, target females and young adult males to increase chances of making real change in behavioural attitudes in these at-risk groups.PMID:37475793 | PMC:PMC10356218 | DOI:10.1155/2023/9318984
Source: Biomed Res - July 21, 2023 Category: Research Authors: Samuel Amoah Andrew Nicholas Yartey Praise Fosu Adjei Margaret Owusu-Akyaw Joseph Boachie David Larbi Simpong Patrick Adu Source Type: research

Acceptance, availability, and feasibility of RTS, S/AS01 malaria vaccine: A review
ConclusionSeveral challenges need to be addressed to ensure the success of vaccination programs. From the acceptability perspective, issues such as inadequate community engagement, concerns about side effects, and issues with the delivery and quality of healthcare services can affect the acceptance of the vaccine. From the feasibility standpoint, factors such as lack of transportation or long distances to healthcare facilities and the perception of completion of the vaccination calendar can affect the feasibility of the vaccine. Lastly, the availability of the vaccine is also a major concern as it may not be readily availa...
Source: Immunity, Inflammation and Disease - June 14, 2023 Category: Allergy & Immunology Authors: Hassan Mumtaz, Abdullah Nadeem, Wajeeha Bilal, Farrukh Ansar, Saira Saleem, Qaisar Ali Khan, Tamara Tango, Christopher Farkouh, Naod F. Belay, Ravina Verma, Matthew Farkouh, Muhammad Saqib Tags: REVIEW ARTICLE Source Type: research

Genetic variations of Plasmodium falciparum circumsporozoite protein and the impact on interactions with human immunoproteins and malaria vaccine efficacy
This study examined polyclonal infections and the associations of parasite genetic variations with binding affinity to human leukocyte antigen (HLA). Multiplicity of infection was determined by amplicon deep sequencing of PfMSP1. Genetic variations in PfCSP were examined across 88 samples from Ghana and analyzed together with 1655 PfCSP sequences from other African and non-African isolates. Binding interactions of PfCSP peptide variants and HLA were predicted using NetChop and HADDOCK. High polyclonality was detected among infections, with each infection harboring multiple non-3D7 PfCSP variants. Twenty-seven PfCSP haploty...
Source: Infection, Genetics and Evolution - February 25, 2023 Category: Genetics & Stem Cells Authors: Cheikh Cambel Dieng Colby T Ford Anita Lerch Dickson Doniou Kovidh Vegesna Daniel Janies Liwang Cui Linda Amoah Yaw Afrane Eugenia Lo Source Type: research

Cost of introducing and delivering RTS,S/AS01 malaria vaccine within the malaria vaccine implementation program
This study estimates the incremental costs of introducing and delivering the malaria vaccine within routine immunization programs in the context of malaria vaccine pilot introduction, to help inform decision-making.METHODS: An activity-based, retrospective costing was conducted from the governments' perspective. Vaccine introduction and delivery costs supported by the donors during the pilot introduction were attributed as costs to the governments under routine implementation. Detailed resource use data were extracted from the pilot program expenditure and activity reports for 2019-2021. Primary data from representative he...
Source: Vaccine - January 29, 2023 Category: Allergy & Immunology Authors: Ranju Baral Ann Levin Chris Odero Clint Pecenka John Tanko Bawa Kwadwo Odei Antwi-Agyei Kwame Amponsa-Achaino Mike Nenani Chisema Rose Eddah Jalango Rouden Mkisi Scott Gordon Winthrop Morgan Farzana Muhib Source Type: research

Where is the 'C' in ANC and PNC: a multi-country survey of availability of Antenatal and Postnatal Care in low- and middle-income settings
CONCLUSIONS: Essential components of ANC and PNC are not in place. Focused attention on content is required if perinatal mortality and maternal morbidity during and after pregnancy are to be reduced.PMID:35106907 | DOI:10.1111/1471-0528.17106
Source: BJOG : An International Journal of Obstetrics and Gynaecology - February 2, 2022 Category: OBGYN Authors: Barbara Madaj Somasundari Gopalakrishnan Alexandre Quach Simone Filiaci Adama Traore Dankom Bakusa Mselenge Mdegela Abdul Wali Yousofzai Ahmed Javed Rahmanzai Grace Kodindo Jean-Pierre Gami Njiki Dounou Rostand Hamit Kessely Stephen Ayisi Addo Mercy Abbey Source Type: research

Towards large-scale identification of HLA-restricted T cell epitopes from four vaccine candidate antigens in a malaria endemic community in Ghana
In conclusion, CSP and AMA1 have relatively higher numbers of epitopes that trigger IFN-γ and granzyme B-secreting T cells in adults with life-long malaria parasite exposure compared to the other two antigens tested, and highlights the continued relevance of these two antigens as vaccine candidates.PMID:34969544 | DOI:10.1016/j.vaccine.2021.12.042
Source: Vaccine - December 31, 2021 Category: Allergy & Immunology Authors: Kwadwo Asamoah Kusi Ebenezer Addo Ofori Kwadwo Akyea-Mensah Eric Kyei-Baafour Augustina Frimpong Nana Aba Ennuson Maria Belmonte Harini Ganeshan Jun Huang Linda Eva Amoah Eileen Villasante Martha Sedegah Source Type: research

Estimated Rates of Intermittent Preventive Treatment During Pregnancy for Malaria Based on Population-based Survey Responses: Reliability of Recall Among Women with Antenatal Care Cards
Am J Trop Med Hyg. 2021 Jun 28:tpmd201296. doi: 10.4269/ajtmh.20-1296. Online ahead of print.ABSTRACTLarge household surveys performed to estimate coverage rates for various health interventions, including intermittent preventive treatment, depend on recall. Many studies question the validity of recalled data. Regarding vaccine coverage rates, it is standard practice to validate responses using medical history cards. To validate the coverage rates of intermittent preventive treatment during pregnancy reported by large household surveys, recalled coverage rates were compared with antenatal care card data in Benin, Ghana, Ma...
Source: Am J Trop Med Hyg - June 28, 2021 Category: Infectious Diseases Authors: Natasha Hansen Susan Youll Lia Florey Cameron Taylor Source Type: research