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Specialty: Neuroscience
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Total 250 results found since Jan 2013.

Integration of an Actor-Critic Model and Generative Adversarial Networks for a Chinese Calligraphy Robot
Publication date: Available online 16 January 2020Source: NeurocomputingAuthor(s): Ruiqi Wu, Changle Zhou, Fei Chao, Longzhi Yang, Chih-Min Lin, Changjing ShangAbstractAs a combination of robotic motion planning and Chinese calligraphy culture, robotic calligraphy plays a significant role in the inheritance and education of Chinese calligraphy culture. Most existing calligraphy robots focus on enabling the robots to learn writing through human participation, such as human-robot interactions and manually designed evaluation functions. However, because of the subjectivity of art aesthetics, these existing methods require a l...
Source: Neurocomputing - January 16, 2020 Category: Neuroscience Source Type: research

Associations Between Two Single-Nucleotide Polymorphisms in NINJ2 Gene and Risk of Psychiatric Disorders
AbstractNINJ2 encodes a transmembrane protein that contributes in neurodevelopment and regeneration of neurons. Single-nucleotide polymorphisms (SNPs) within this gene have been associated with Alzheimer ’s disease, ischemic stroke, and multiple sclerosis. The rs11833579 and rs3809263 SNPs have been associated with risk of ischemic stroke in Iranian population. While theNINJ2 rs12425791 has been with risk of ischemic stroke in East Asian population, the rs11833579 has not been associated with this condition either in East Asian population or Chinese Han population. In the current project, we genotyped rs11833579 and rs38...
Source: Journal of Molecular Neuroscience - December 22, 2019 Category: Neuroscience Source Type: research

Association of serum growth differentiation factor 15 level with acute ischemic stroke in a Chinese population
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Source: International Journal of Neuroscience - September 5, 2019 Category: Neuroscience Authors: Xiaoyu Dong Jianfei Nao Source Type: research

SSNet: Structure-Semantic Net for Chinese Typography Generation based on Image Translation
Publication date: Available online 30 August 2019Source: NeurocomputingAuthor(s): Jianwei Zhang, Danni Chen, Guoqiang Han, Guanzhao Li, Junting He, Zhenmei Liu, Zhihui RuanAbstractThe abundant complex Chinese characters often lead to the high cost of time and labor in its typography production, which cannot meet various demands of typohraphies in daily life. Image translation methods are becoming the mainstream of typography generation to facilitate typography production. Nevertheless, current translation methods do not take the Chinese semantics and structure into account. In this paper, we propose a method called Structu...
Source: Neurocomputing - August 31, 2019 Category: Neuroscience Source Type: research

Association of COL4A2 Gene Polymorphisms with Lacunar Stroke in Xinjiang Han Populations
This study demonstrates that the COL4A2 gene could play a role in the pathogenesis of lacunar stroke in the Han population of China.
Source: Journal of Molecular Neuroscience - August 10, 2019 Category: Neuroscience Source Type: research

Dl-3-N-Butylphthalide Alleviates the Blood–Brain Barrier Permeability of Focal Cerebral Ischemia Reperfusion in Mice
In conclusion, NBP exerts neuroprotective effects through attenuating cerebral infarct volume and neurological deficit score, reducing cerebral edema and BBB permeability. The neuroprotective effect of NBP is possibly related to its ability to improve blood flow in cerebral ischemic areas. NBP may turn into a novel treatment drug to prevent BBB dysfunction in ischemic stroke.
Source: Neuroscience - June 26, 2019 Category: Neuroscience Source Type: research

Protective effect of gastrodin against methamphetamine-induced autophagy in human dopaminergic neuroblastoma SH-SY5Y cells via the AKT/mTOR signaling pathway
This study investigates whether METH induces autophagy in the human dopaminergic neuroblastoma cell line SH-SY5Y, then examines the neuroprotective effects of gastrodin against autophagy in METH-treated SH-SY5Y cells. The effects of METH on the protein expressions of autophagy-related genes (LC3B and Beclin-1) were evaluated with and without gastrodin. The presence of autophagosomes in the METH-induced treatment with and without gastrodin is revealed through transmission electron microscopy. Pharmacological intervention was employed to study the role of the AKT/mTOR signaling pathway in the gastrodin-mediated neuroprotecti...
Source: Neuroscience Letters - May 24, 2019 Category: Neuroscience Source Type: research

Association of miR-122, miR-124 miR-126 and miR-143 gene polymorphisms with ischemic stroke in the northern Chinese Han population
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Source: International Journal of Neuroscience - May 14, 2019 Category: Neuroscience Authors: Ruixia Zhu Xu Liu Zhiyi He Source Type: research

Morphological and Whole-Word Semantic Processing Are Distinct: Event Related Potentials Evidence From Spoken Word Recognition in Chinese
In conclusion, the present study provides electrophysiological evidence of the dissociation of morphological and whole-word semantic processing in Chinese spoken word processing. The results identified a central-anterior morphological N400 effect when morphemic meaning conflicts with whole-word semantics, in addition to a classic semantic N400 effect with significantly reduced amplitude in central-parietal areas. Our results also showed that the morphological N400 effect is negatively correlated with reading ability. These results demonstrate the important role of morphological processing in Chinese spoken word recognition...
Source: Frontiers in Human Neuroscience - April 16, 2019 Category: Neuroscience Source Type: research

Collectivism Is Associated With Greater Neurocognitive Fluency in Older Adults
This study aimed to evaluate the impact of self-construal on neurocognitive functions in older adults. A total of 86 community-dwelling older adults 60 years and older were assessed with three common self-report measures of self-construal along individualism and collectivism (IC). A cognitive battery was administered to assess verbal and non-verbal fluency abilities. Latent profile analysis (LPA) was used to categorize individuals according to IC, and one-way analyses of covariance (ANCOVA), including relevant covariates (e.g., ethnicity, gender, linguistic abilities), were used to compare neurocognitive functions between ...
Source: Frontiers in Human Neuroscience - April 10, 2019 Category: Neuroscience Source Type: research

Association of miR-122, miR-124 miR-126 and miR-143 gene polymorphisms with ischemic stroke in the northern Chinese Han population
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Source: International Journal of Neuroscience - March 20, 2019 Category: Neuroscience Authors: Ruixia Zhu Xu Liu Zhiyi He Source Type: research

Astragaloside IV Protects Primary Cerebral Cortical Neurons from Oxygen and Glucose Deprivation/Reoxygenation by Activating the PKA/CREB Pathway
Publication date: Available online 30 January 2019Source: NeuroscienceAuthor(s): Bingjie Xue, Jisheng Huang, Bo Ma, Bin Yang, Dennis Chang, Jianxun LiuAbstractStroke is one of the major leading causes of death and disability worldwide, and post-stroke cognitive impairment is a major contributor to this disability. Astragaloside IV (AST-IV) is a primary bioactive compound of Radix Astragali, which is widely used in traditional Chinese medicine to treat stroke. AST-IV was found to possess cognition-enhancing properties against ischemic stroke; however, the mechanisms underlying this effect remain largely elusive. Mitochondri...
Source: Neuroscience - January 30, 2019 Category: Neuroscience Source Type: research

L-NBP, a multiple growth factor activator, attenuates ischemic neuronal impairments possibly through promoting neuritogenesis
Publication date: Available online 7 January 2019Source: Neurochemistry InternationalAuthor(s): Yuming Zhao, Dongmei Liu, Jiang Li, XiaoJie Zhang, Xiaoliang WangAbstractIn China, L-3-n-butylphthalide (L-NBP) showed promising pharmacological actions in stroke treatment. Analyzing the characteristics of L-NBP might provide valuable hints for new drug design. The current study is aimed to determine the effects of L-NBP on neuritogenesis and further to elucidate the neuronal protection against stroke impairment in vitro. L-NBP was applied to rat pheochromocytoma PC12 cells and cultured rat cortical neurons under the normoxic...
Source: Neurochemistry International - January 7, 2019 Category: Neuroscience Source Type: research

HDAC9 Polymorphisms Predict Susceptibility, Severity, and Short-Term Outcome of Large Artery Atherosclerotic Stroke in Chinese Population
This study aimed to investigate whether these two polymorphisms were associated with susceptibility, severity, and short-term outcome of LAA stroke in a southern Chinese Han population. rs2074633 and rs28688791 were genotyped using SNPscan technology in 1011 LAA stroke patients and 1121 healthy controls. Stroke severity on admission and short-term outcome were, respectively, assessed by the National Institute of Health Stroke Scale (NIHSS) score on admission and modified Rankin Scale score at 3  months after stroke onset. rs2074633 (P = 0.039) and rs28688791 (P = 0.025) were associated with risk of LAA stroke. In ...
Source: Journal of Molecular Neuroscience - December 18, 2018 Category: Neuroscience Source Type: research