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Vaccination in pediatric acquired inflammatory immune-mediated neuromuscular disorders
CONCLUSION: s: There are no strong evidence supporting relationship between vaccination with different pediatric vaccines and development of first episodes or reccurrences of GBS, Bell's palsy, optic neuritis (ON), juvenile MG, CIDP, and IM. The vaccination and revaccination with inactivated vaccines is considered safe in children with medical history of GBS, Bell's palsy, ON, MG and IM. Caution when immunization against influenza, quadrivalent conjugated meningococcal vaccine (MCV4) and pneumococcal disease and avoiding tetanus toxoid immunization in CIDP patients is suggested. Patients with immune mediated acquired NMD s...
Source: European Journal of Paediatric Neurology - January 8, 2022 Category: Neurology Authors: Nina Bari ši? Daniel Turudi ? Lorna Stemberger Mari ? Goran Te šovi? Source Type: research

Vaccination and childhood epilepsies
CONCLUSIONS: There is no evidence that vaccinations cause epilepsy in healthy populations. Vaccinations do not cause epileptic encephalopathies but may be non-specific triggers to seizures in underlying structural or genetic etiologies. The first seizure in DS may be earlier in vaccinated versus non-vaccinated patients, but developmental outcome is similar in both groups. Children with a personal or family history of FS or epilepsy should receive all routine vaccinations. This recommendation includes DS. The known risks of the infectious diseases prevented by immunization are well established. Vaccination should be deferre...
Source: European Journal of Paediatric Neurology - December 18, 2021 Category: Neurology Authors: Dana Craiu Zvonka Rener Primec Lieven Lagae Federico Vigevano Eugen Trinka Nicola Specchio Sophia Bakhtadze Cristina Cazacu Tanja Golli Sameer M Zuberi Source Type: research

Uptake and Attitudes About Immunizations in People With Multiple Sclerosis
Conclusion Vaccination uptake is lower than desired in the MS population compared with existing recommendations, including for seasonal influenza. Misconceptions about the safety of vaccination in the context of MS and personal preference appear to play important roles in vaccination choices, highlighting the importance of education about these issues.
Source: Neurology Clinical Practice - August 9, 2021 Category: Neurology Authors: Marrie, R. A., Kosowan, L., Cutter, G. R., Fox, R., Salter, A. Tags: Multiple sclerosis, All epidemiology Research Source Type: research

The Value of 3T MRI in Acute Transverse Myelitis
An 11 year old girl presented with 18 hours of right leg weakness and left leg numbness. Past medical history was significant for a two day viral gastroenteritis 25 days prior and vaccinations 24 days prior (Tetanus, diphtheria, and pertussis; human papilloma virus; influenza; and meningococcal). Initial exam pertinent findings were right leg weakness (0/5 proximally and 3/5 distally), absent left leg temperature sense to the groin area without anesthesia or left hemibody sensory level, and inconsistent decreased right patellar reflex and extensor plantar response.
Source: Pediatric Neurology - August 11, 2014 Category: Neurology Authors: Erica Austin, Daniel Arndt, Branford Betz Source Type: research

The Value of 3-T Magnetic Resonance Imaging in Acute Transverse Myelitis
An 11-year-old girl presented with 18 hours of right leg weakness and left leg numbness. Past medical history was significant for a 2-day viral gastroenteritis 25 days prior and vaccinations 24 days prior (tetanus, diphtheria, and pertussis; human papilloma virus; influenza; and meningococcal). Initial examination findings included right leg weakness (0/5 proximally and 3/5 distally), absent left leg temperature sensation to the groin area without anesthesia or left hemibody sensory level, and inconsistent decreased right patellar reflex and extensor plantar response.
Source: Pediatric Neurology - August 11, 2014 Category: Neurology Authors: Erica Austin, Daniel Arndt, Bradford Betz Tags: Visual Diagnosis Source Type: research

CLINICAL PROFILE AND OUTCOME OF ADULT TETANUS IN OGHARA, DELTA STATE , NiGERIA (P1.309)
CONCLUSION:Tetanus is life-threatening disease with high case fatality that is still a major health in our environment. There is need to provide better vaccination coverage for all including booster doses for adult males and to improve on medical intensive care facilities and training.Disclosure: Dr. Obiabo has received personal compensation for activities with Novartis as a speaker.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Obiabo, Y. Tags: Other Bacterial Infections Source Type: research

Vaccine Boosts Glioblastoma SurvivalVaccine Boosts Glioblastoma Survival
A novel combination of cytomegalovirus-targeted dendritic cell vaccine and tetanus preconditioning shows a significant increase in survival and improved immune response in glioblastoma. Medscape Medical News
Source: Medscape Neurology and Neurosurgery Headlines - May 12, 2016 Category: Neurology Tags: Neurology & Neurosurgery News Source Type: news

Tetanus, Botulism, and Diphtheria
This article reviews the pathophysiology, epidemiology, clinical manifestations, diagnosis, and treatment of tetanus, botulism, and diphtheric neuropathy. RECENT FINDINGS Tetanus is most common in lower-income settings, but rare cases are seen in higher-income settings because of the inadequate maintenance of vaccination status. Foodborne botulism remains rare, but botulism can also be caused by IV drug use (wound botulism) and medical use of botulinum toxin (iatrogenic botulism); botulinum toxin has also been considered a potential agent of bioterrorism. Diphtheric neuropathy is rare but has been seen in recent epidemi...
Source: CONTINUUM: Lifelong Learning in Neurology - October 1, 2018 Category: Neurology Tags: Review Articles Source Type: research

Immunomodulation through vaccination as a promising therapeutic strategy to mitigate malaria-related neurocognitive sequelae
Brain Behav Immun. 2023 Jan 16:S0889-1591(23)00007-7. doi: 10.1016/j.bbi.2023.01.007. Online ahead of print.ABSTRACTMalaria, an ancient infectious parasitic disease, is caused by protozoa of the genus Plasmodium, whose erythrocytic cycle is accompanied by fever, headache, sweating and chills and a systemic inflammation that can progress to severe forms of disease, including cerebral malaria. Approximately 25% of survivors of this syndrome develop sequelae that may include neurological, neurocognitive, behavioral alterations and poor school performance. Furthermore, some outcomes have also been recorded following episodes o...
Source: Brain, Behavior, and Immunity - January 19, 2023 Category: Neurology Authors: Pamela Rosa-Gon çalves Luciana Pereira de Sousa Fl ávia Lima Ribeiro-Gomes Leonardo Jos é de Moura Carvalho Cl áudio Tadeu Daniel-Ribeiro Source Type: research