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Data Doesn ’t Support New COVID-19 Booster Shots for Most, Says Vaccine Expert
In a perspective published Jan. 11 in the New England Journal of Medicine, vaccine expert Dr. Paul Offit says it’s time to rethink booster recommendations.
In the third year of the pandemic, the population’s immune situation is vastly different from what it was in 2019 when SARS-CoV-2 emerged. Now, most people have been vaccinated against the virus, been infected with it (once or multiple times), or both. And the latest data show that the newest booster shot, which targets the Omicron BA.4/5 strain and original virus variants in a bivalent formulation, isn’t that much more effective in generating virus-fi...
Source: TIME: Health - January 11, 2023 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news
Monkeypox (Mpox) requires continued surveillance, vaccines, therapeutics and mitigating strategies
We describe here the vaccines and drugs available for the prevention and treatment of MPXV infections. However, although their efficacy against monkeypox (mpox) has been established in animal models, little is known about their efficacy in the current outbreak setting. The continuing opportunity for transmission raises concerns about the potential for evolution of the virus and for expansion beyond the current risk groups. The priorities for action are clear: 1) more data on the efficacy of vaccines and drugs in infected humans must be gathered; 2) global collaborations are necessary to ensure that government authorities w...
Source: Vaccine - April 23, 2023 Category: Allergy & Immunology Authors: Rachel L Roper Alfredo Garzino-Demo Carlos Del Rio Christian Br échot Robert Gallo William Hall Jos é Esparza Marvin Reitz Raymond F Schinazi Mark Parrington James Tartaglia Marion Koopmans Jorge Osorio Andreas Nitsche Tan Boon Huan James LeDuc Antoine Source Type: research
Drugged Water: A New Global Pandemic Hiding in Plain Sight?
Credit: WHOBy Baher KamalMADRID, Apr 13 2022 (IPS) People around the world are unknowingly being exposed to water laced with antibiotics, which could spark the rise of drug-resistant pathogens and potentially fuel another global pandemic, warns a new report.
The study, elaborated by the United Nations Environment Programme (UNEP), found that, globally, not enough attention is being focused on the threat posed by antimicrobial resistance with most antibiotics being excreted into the environment via toilets or through open defecation.
Already in 2015, 34.8 billion daily doses of antibiotics were consumed, with up to 90 perce...
Source: IPS Inter Press Service - Health - April 13, 2022 Category: International Medicine & Public Health Authors: Baher Kamal Tags: Development & Aid Environment Global Headlines Health TerraViva United Nations Water & Sanitation Source Type: news
Monkeypox (Mpox) requires continued surveillance, vaccines, therapeutics and mitigating strategies
We describe here the vaccines and drugs available for the prevention and treatment of MPXV infections. However, although their efficacy against monkeypox (mpox) has been established in animal models, little is known about their efficacy in the current outbreak setting. The continuing opportunity for transmission raises concerns about the potential for evolution of the virus and for expansion beyond the current risk groups. The priorities for action are clear: 1) more data on the efficacy of vaccines and drugs in infected humans must be gathered; 2) global collaborations are necessary to ensure that government authorities w...
Source: Vaccine - April 21, 2023 Category: Allergy & Immunology Authors: Rachel L Roper Alfredo Garzino-Demo Carlos Del Rio Christian Br échot Robert Gallo William Hall Jos é Esparza Marvin Reitz Raymond F Schinazi Mark Parrington James Tartaglia Marion Koopmans Jorge Osorio Andreas Nitsche Tan Boon Huan James LeDuc Antoine Source Type: research
A Novel Thermal Method to Inactivate Rotavirus for Use in Vaccines
Rotavirus is a highly contagious, diarrhea-inducing pathogen that annually causes approximately 250,000 deaths worldwide and millions of hospitalizations, especially afflicting infants and young children. One strategy to combat this virus is through vaccination. Continuing safety and efficacy concerns with the currently existing live, oral vaccines against rotavirus have led researchers to search for alternative treatment approaches, such as vaccines containing inactivated rotavirus.This technology describes a method for inactivating rotavirus. Traditional inactivation strategies use chemicals that reduce antigenicity (by ...
Source: NIH OTT Licensing Opportunities - January 16, 2018 Category: Research Authors: ajoyprabhu3 Source Type: research
Strategies Towards Protease Inhibitors for Emerging Flaviviruses.
Authors: Nitsche C
Abstract
Infections with flaviviruses are a continuing public health threat. In addition to vaccine development and vector control, the search for antiviral agents that alleviate symptoms in patients are of considerable interest. Among others, the flaviviral protease NS2B-NS3 is a promising drug target to inhibit viral replication. Flaviviral proteases share a high degree of structural similarity and substrate-recognition profile, which may facilitate a strategy towards development of pan-flaviviral protease inhibitors. However, the success of various drug discovery attempts during the last decad...
Source: Advances in Experimental Medicine and Biology - June 1, 2018 Category: Research Tags: Adv Exp Med Biol Source Type: research
A Novel Thermal Method to Inactivate Rotavirus for Use in Vaccines
Rotavirus is a highly contagious, diarrhea-inducing pathogen that annually causes approximately 250,000 deaths worldwide and millions of hospitalizations, especially afflicting infants and young children. One strategy to combat this virus is through vaccination. Continuing safety and efficacy concerns with the currently existing live, oral vaccines against rotavirus have led researchers to search for alternative treatment approaches, such as vaccines containing inactivated rotavirus.This technology describes a method for inactivating rotavirus. Traditional inactivation strategies use chemicals that reduce antigenicity (by ...
Source: NIH OTT Licensing Opportunities - January 16, 2018 Category: Research Authors: ott-admin Source Type: research
Cutaneous anthrax associated with handling carcasses of animals that died suddenly of unknown cause: Arua District, Uganda, January 2015 –August 2017
ConclusionsExposure to carcasses of animals that died suddenly was a likely risk factor for cutaneous anthrax in Arua District during 2015 –2017. The recommendations are investigation of anthrax burden in livestock, prevention of animal infections through vaccinations, safe disposal of the carcasses, public education on risk factors for infection and prompt treatment of illness following exposure to animals that died suddenly.
Source: PLoS Neglected Tropical Diseases - August 23, 2021 Category: Tropical Medicine Authors: Freda Loy Aceng Source Type: research
News at a glance: Webb telescope dinged, U.S.-Russia research paused, and NASA ’s UFO study
Table of contents
A version of this story appeared in Science, Vol 376, Issue 6599.
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ASTRONOMY
Star mapper provides Milky Way portrait
he European Space Agency’s Gaia satellite has now mapped almost 2 billion of the Milky Way’s stars, logging their positions, speeds, temperatures, and other parameters—and allowing astronomers to chart the Galaxy’s structure and evolution. Last week, operators released the third major trove of data, including lists of 800,000 binary stars, 10 million variable stars, and, within the Solar System, 156,000...
Source: Science of Aging Knowledge Environment - June 16, 2022 Category: Geriatrics Source Type: research
Knowledge, Attitude and Perception of Ebola Virus Disease among Secondary School Students in Ondo State, Nigeria, October, 2014
Conclusion
We recommended the promotion and sustainability of health messages focusing on the mode of transmission and preventive measures such as demonstration of hand-washing techniques, addressing myths and misconceptions; and promoting safe burial practices. The public health action that followed this survey was the commencement of school health education and training of students on prevention of EVD in Owo Local Government Area of Ondo State, Nigeria. This should be extended to other schools across Nigeria.
Competing Interests
The authors have declared that no competing interests exist.
Source: PLOS Currents Outbreaks - March 4, 2016 Category: Epidemiology Authors: plosyinka01 Source Type: research
A Mysterious Company Claims to Sell Sneeze-Filled Tissues for $80. Is It Real?
The package appeared one day, unbidden, on the desk of a TIME writer. Inside was a slick white box that housed a petri dish sealed with gold tape. In the dish was a crumpled tissue—and inside the tissue were, allegedly, the germs of a sick person who had sneezed into it.
Vaev Tissue, the only product of a new startup based in Los Angeles, costs $79.99, according to the company’s website. Its sole purpose is to give the user a cold virus. “We believe using a tissue that carries a human sneeze is safer than needles or pills,” read the note that came with the product, written by the founder of the comp...
Source: TIME: Health - January 18, 2019 Category: Consumer Health News Authors: Mandy Oaklander Tags: Uncategorized public health Source Type: news
Wuhan Coronavirus Infections Have Now Surpassed the Official Number of SARS Cases in China
Chinese officials confirmed Wednesday that the number of people infected by a new form of coronavirus in the country has reached 5,974, a total that surpasses the official cases tallied on the mainland during an outbreak of severe acute respiratory syndrome (SARS) in 2002 and 2003. SARS infected 5,237 people in mainland China, and killed almost 800 people across the world.
The new SARS-like form of coronavirus has killed 132 people in China. The disease, which is believed to have originated in a seafood market in the Chinese central city of Wuhan, has also spread to other countries, including the U.S., where five cases hav...
Source: TIME: Health - January 27, 2020 Category: Consumer Health News Authors: Sanya Mansoor and Amy Gunia Tags: Uncategorized China Infectious Disease onetime overnight Source Type: news
How Our Modern World Creates Outbreaks Like Coronavirus
“Everyone knows that pestilences have a way of recurring in the world,” observes Albert Camus in his novel The Plague. “Yet somehow we find it hard to believe in ones that crash down on our heads from a blue sky. There have been as many plagues as wars in history; yet plagues and wars always take people by surprise.”
Camus was imagining a fictional outbreak of plague in 1948 in Oran, a port city in northwest Algeria. But at a time when the world is reeling from a very real microbial emergency sparked by the emergence of a novel coronavirus in Wuhan, central China, his observations are as pertinent a...
Source: TIME: Health - February 7, 2020 Category: Consumer Health News Authors: Mark Honigsbaum Tags: Uncategorized 2019-nCoV health ideas Source Type: news
