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Vaccination: Cancer Vaccines

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Addressing disparities in cancer care and incorporating precision medicine for minority populations
J Natl Med Assoc. 2023 Mar 29:S0027-9684(23)00030-5. doi: 10.1016/j.jnma.2023.02.001. Online ahead of print.ABSTRACTCancer incidence and outcomes vary considerably between racial and ethnic groups. Non-Hispanic (NH) Blacks are disproportionately burdened with the most common cancer types, having the highest death rate of any group. Racial health disparities are complex and have been identified at each step of the cancer care continuum, encompassing patient and provider factors and health care system processes. The higher cancer mortality among NH Blacks may reflect underuse of prevention strategies such as vaccination and ...
Source: Journal of the National Medical Association - March 31, 2023 Category: General Medicine Authors: Robert Winn Karen Winkfield Edith Mitchell Source Type: research

What Are Treatments for Recurrent Respiratory Papillomatosis?
Discussion Human papilloma virus (HPV) is a member of the Papillomaviridae virus family with over a 150 different subtypes. HPV can cause cervical, genital and respiratory tract papillomas. HPV is often benign but can cause anogenital, cervical and head and neck cancers. Recurrent respiratory papillomatosis (RRP) is uncommon but can cause significant morbidity while awaiting the body’s immune system to respond. There is a juvenile and adult form, and the incidence varies between 2-4/100,000 in the pediatric population. The juvenile form frequently occurs between 3.6-6 years of age and in general the younger the patie...
Source: PediatricEducation.org - July 31, 2023 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Awareness, knowledge and beliefs about HPV, cervical cancer and HPV vaccines among nurses in Cameroon: An exploratory study
Conclusion: Despite high awareness about HPV, more education about the virus, cervical cancer and the vaccine are required to further increase nurses’ willingness to recommend the vaccine and strengthen strategies for reaching adolescents through nurses in Cameroon.
Source: International Journal of Nursing Studies - February 11, 2013 Category: Nursing Authors: Richard G. Wamai, Claudine Akono Ayissi, Geofrey O. Oduwo, Stacey Perlman, Edith Welty, Thomas Welty, Simon Manga, Monica A. Onyango, Javier Gordon Ogembo Tags: Education and Professional Development Source Type: research

Adoptive T-cell Transfer Therapy and Oncogene-Targeted Therapy for Melanoma: The Search for Synergy.
Abstract The clinical strengths of immunotherapy and small-molecule inhibitors targeting the mitogen-activated protein kinase (MAPK) pathway appear to be largely complementary for the treatment of advanced melanoma. In current practice, most patients with BRAF V600 mutant melanomas will see both modalities. Several in vitro and in vivo studies suggest that combining immunotherapy with MAPK inhibition may have synergistic effects. First, mouse models show that adoptive cell therapy (ACT) can be enhanced by vaccination. Rapid tumor destruction by vemurafenib could provide a vaccine-like stimulus to adoptively transf...
Source: Clinical Cancer Research - October 1, 2013 Category: Cancer & Oncology Authors: Kwong ML, Neyns B, Yang JC Tags: Clin Cancer Res Source Type: research

Culturally Appropriate Photonovel Development and Process Evaluation for Hepatitis B Prevention in Chinese, Korean, and Vietnamese American Communities
Asian Americans have disproportionately high prevalence of chronic hepatitis B virus infection in the United States and yet have low hepatitis B screening and vaccination rates. We developed three photonovels specifically designed for Chinese, Korean, and Vietnamese Americans and evaluated their cultural relevance and effectiveness in increasing self-efficacy and intention to have a hepatitis B screening. Photonovels’ storylines were drawn from focus group themes, and lay people from each community played actors/actresses in community settings. Photonovels were pilot tested, revised, and distributed in a hepatitis B ...
Source: Health Education - November 12, 2013 Category: Health Management Authors: Lee, S., Yoon, H., Chen, L., Juon, H.-S. Tags: Articles Source Type: research

Oncology nurses' knowledge of survivorship care planning: the need for education.
Conclusions: Oncology nurses at an academic comprehensive cancer center reported gaps in knowledge consistent with previous studies about knowledge of survivorship care.Implications for Nursing: The Institute of Medicine has challenged oncology providers to address cancer survivorship care planning. Gaps in cancer survivorship knowledge are evident and will require focused education for this initiative to be successful. PMID: 24578084 [PubMed - in process]
Source: Oncology Nursing Forum - March 1, 2014 Category: Nursing Authors: Lester JL, Wessels AL, Jung Y Tags: Oncol Nurs Forum Source Type: research

The Effectiveness of a Facebook-Assisted Teaching Method on Knowledge and Attitudes About Cervical Cancer Prevention and HPV Vaccination Intention Among Female Adolescent Students in Taiwan
Conclusions. School-based cervical cancer prevention education can be effective. The Facebook-assisted discussion method was more effective than the in-person discussion. Providing the human papillomavirus vaccine free of charge would increase female adolescents’ intention to be vaccinated.
Source: Health Education - May 25, 2015 Category: Health Management Authors: Lai, C.-Y., Wu, W.-W., Tsai, S.-Y., Cheng, S.-F., Lin, K.-C., Liang, S.-Y. Tags: Articles Source Type: research

Abstract IA07: In search of racial disparities in HPV vaccination
Background: Racial disparities in cervical cancer deaths are longstanding, with African American and Latina women more likely to die from the disease. The advent of HPV vaccine created an opportunity to reduce or end these disparities, but only if uptake was either uniformly high across all females or higher among minority than non-minority females. Thus, interest in racial disparities in HPV vaccine coverage has been understandably high.Findings: Data from several sources show racial disparities and "reverse disparities" in HPV vaccination coverage. First, the most reliable national data are from the National Immunization...
Source: Cancer Epidemiology Biomarkers and Prevention - September 30, 2015 Category: Cancer & Oncology Authors: Brewer, N. T., Moss, J. L., Reiter, P. L. Tags: Vaccines and Immunoprevention: Oral Presentations - Invited Abstracts Source Type: research

Increasing Cervical Cancer and Human Papillomavirus Prevention Knowledge and HPV Vaccine Uptake through Mother/Daughter Education.
Authors: Obulaney PA, Gilliland I, Cassells H Abstract This evidence-based initiative assessed the impact of language-appropriate cervical cancer and human papillomavirus (HPV) prevention education on knowledge level and HPV vaccine uptake among mothers and their daughters. Forty-one mother/daughter dyads from a low-cost, faith-based clinic for the uninsured in southeastern Texas participated in the nurse practitioner-led cervical cancer prevention educational sessions. Spanish was the primary language for the majority of participating mothers. The project produced appreciable knowledge increase and HPV vaccine upt...
Source: Journal of Community Health Nursing - January 28, 2016 Category: Nursing Tags: J Community Health Nurs Source Type: research

Human Papillomavirus (HPV) Vaccination Motivators, Barriers, and Brochure Preferences Among Parents in Multicultural Hawai‘i: a Qualitative Study
Abstract The human papillomavirus (HPV) vaccine can prevent cervical and other cancers. Unfortunately, according to the National Immunization Survey—Teen 2014 data, completion of the HPV vaccine was only 38 % for 13- to 17-year-old girls and 31 % for 13- to17-year-old boys in the USA, and prevalence was similar in Hawai‘i. Parents’ acceptability of the HPV vaccine is critical for the vaccine uptake, and this can be increased by educational materials and interventions. However, HPV materials are not widely distributed in Hawai‘i. The purpose of this qualitative study was to identify HPV vaccination barrie...
Source: Journal of Cancer Education - March 7, 2016 Category: Cancer & Oncology Source Type: research

Pilot Test of Survey to Assess Dental and Dental Hygiene Student Human Papillomavirus-Related Oropharyngeal Cancer Knowledge, Perceptions, and Clinical Practices
AbstractThis was the first study to develop and pilot test an assessment tool for the examination of human papillomavirus (HPV)-related oropharyngeal cancer (OPC) knowledge, perceptions, and clinical practices of oral health students. An interdisciplinary team developed the tool using surveys that examined this topic in other populations. The tool was then pilot tested at two different dental programs. Results from the pilot informed revisions to the final version of the tool. Of the 46 student participants, 18 were first-year dental hygiene and 28 were first-year dental students. The majority of participants were female (...
Source: Journal of Cancer Education - January 13, 2017 Category: Cancer & Oncology Source Type: research

Prevention of HPV-Related Oral Cancer by Dentists: Assessing the Opinion of Dutch Dental Students
AbstractThe aim of this study is to assess dental students ’ opinions of the dentists’ role in primary prevention of human papillomavirus (HPV)-related oral cancer using a cross-sectional web-based survey. A questionnaire, containing questions about knowledge of HPV and oral cancer, confidence in head and neck examination and role of the dentist in prev enting HPV-related oral cancer, was sent to all students of the Academic Centre of Dentistry Amsterdam (n = 912). One hundred and twenty-six (n = 126) students completed the questionnaire. Significantly, more master students (75%) than bachelor students (54.3%) were...
Source: Journal of Cancer Education - July 24, 2017 Category: Cancer & Oncology Source Type: research

Awareness of HPV and Cervical Cancer Prevention Among University Health Sciences Students in Cyprus
The objective of this study was to evaluate the knowledge and awareness of health sciences university students in Cyprus regarding HPV and cervical cancer in order to better guide the future development of educational programs to improve cervical cancer prevention. This was a cross-sectional study of 178 university health sciences students in Cyprus using a validated questionnaire on HPV and cervical cancer prevention. Analysis of the completed questionnaires revealed moderate levels of knowledge and awareness with an overall mean score of 23.32 out of 33 on HPV and 8.12 out of 13 on cervical cancer, a score of 9.25 out of...
Source: Journal of Cancer Education - April 9, 2018 Category: Cancer & Oncology Source Type: research

Cancers, Vol. 10, Pages 492: Recent Advances in Oncolytic Virotherapy and Immunotherapy for Glioblastoma: A Glimmer of Hope in the Search for an Effective Therapy?
nin To date, no targeted drugs, antibodies or combinations of chemotherapeutics have been demonstrated to be more efficient than temozolomide, or to increase efficacy of standard therapy (surgery, radiotherapy, temozolomide, steroid dexamethasone). According to recent phase III trials, standard therapy may ensure a median overall survival of up to 18–20 months for adult patients with newly diagnosed glioblastoma. These data explain a failure of positive non-controlled phase II trials to predict positive phase III trials and should result in revision of the landmark Stupp trial as a historical control for ...
Source: Cancers - December 5, 2018 Category: Cancer & Oncology Authors: Aleksei A. Stepanenko Vladimir P. Chekhonin Tags: Review Source Type: research

Exploring the Need of HPV Education Programs in Korean American Communities.
This study found a lack of knowledge about HPV and the vaccine, along with negative perceptions about the vaccine, affects HPV vaccination decision-making. Ineffective conversations and a lack of HPV vaccine recommendations by health care providers influenced by cultural beliefs were found to be another major barrier. These findings reveal new insights to guide the development of HPV education programs. PMID: 30793961 [PubMed - in process]
Source: Journal of Community Health Nursing - February 24, 2019 Category: Nursing Tags: J Community Health Nurs Source Type: research