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Therapy: Alternative and Complementary Therapies

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Total 320 results found since Jan 2013.

The Role of Cobalamin on Interleukin 10, Osteopontin, and Related MicroRNAs in Multiple Sclerosis
Iran J Allergy Asthma Immunol. 2022 Jun 18;21(3):332-343. doi: 10.18502/ijaai.v21i3.9806.ABSTRACTMultiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system (CNS). Considering how vitamin B12 or cobalamin affects the immune system, especially inflammation and the formation of the myelin sheath, it appears as a complementary therapy for MS by affecting some signaling pathways. Recently diagnosed MS patients were divided into two groups (n=30). One group received interferon-beta (IFN-β or Avonex), and another received IFN-β+B12 for six months. Blood samples were taken before and after treatments...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 13, 2022 Category: Allergy & Immunology Authors: Mohammad Sadegh Hesamian Vahid Shaygannejad Marjan Golabi Omid Mirmosayyeb Alireza Andalib Nahid Eskandari Source Type: research

Guidelines for the Management of Atopic Dermatitis in Children: A Systematic Review
Conclusions: Most guidelines were recommended for use with revision. No significant changes were observed in the primary management of atopic dermatitis in children compared to previous evidence. New biological agents and complementary alternative medicine are increasingly available, but the evidence for the treatment of atopic dermatitis in children is still limited.Int Arch Allergy Immunol
Source: International Archives of Allergy and Immunology - November 2, 2022 Category: Allergy & Immunology Source Type: research

Neutrophilic asthma at an inhibitory checkpoint: A  PD-1–targeted approach
In this issue of the Journal of Allergy and Clinical Immunology, Helou et  al1 provide compelling evidence that programmed cell death protein 1 (PD-1) plays a protective role in an established murine model of acute steroid-resistant neutrophilic asthma.2 Neutrophilic asthma models in mice serve to examine the mechanisms leading to “non–type 2” (non-T2) asthma, in w hich there is an absence of T2 features such as airway eosinophilia. Non-T2 asthma tends to be less responsive to corticosteroids, revealing a need to better understand the mechanism of potential alternative therapies against the immune response that lead...
Source: Journal of Allergy and Clinical Immunology - December 1, 2022 Category: Allergy & Immunology Authors: Nyssa B. Samanas, Ryan C. Murphy, Irina Miralda, Teal S. Hallstrand, Adrian M. Piliponsky Tags: Editorial Source Type: research

Allegations of Failure to Obtain Informed Consent in Otolaryngology: Evidenced-Based Recommendations for Sinus Surgeons
CONCLUSIONS: Failure to obtain informed consent is an important factor in medical malpractice litigation. This report identifies specific, actionable recommendations aimed at protecting sinus surgeons from liability and ensuring that patients are better informed.PMID:36591908 | DOI:10.1177/19458924221148566
Source: American Journal of Rhinology and Allergy - January 2, 2023 Category: ENT & OMF Authors: Christian G Fritz Dominic J Romeo Anne S Lowery Karthik Rajasekaran Source Type: research

Oral JAK Inhibitors for Atopic Dermatitis
Ann Allergy Asthma Immunol. 2023 Jan 31:S1081-1206(23)00075-3. doi: 10.1016/j.anai.2023.01.020. Online ahead of print.ABSTRACTAtopic dermatitis (AD) is one of the most common inflammatory skin conditions. The pathogenesis of AD involves skin barrier disruption and immune activation of T-helper (Th)2 and Th22, as well as varying degrees of Th1 and Th17 activation in various patient subtypes. Although AD is mainly driven by Th2, the molecular and clinical heterogeneity of AD underscores the need for more efficacious treatments that target multiple immune axes. Janus kinase (JAK) inhibitors are novel therapeutics that broadly...
Source: Annals of Allergy, Asthma and Immunology - February 3, 2023 Category: Allergy & Immunology Authors: Daniela Mikhaylov Benjamin Ungar Yael Renert-Yuval Emma Guttman-Yassky Source Type: research

Role of Mesenchymal Stem Cells and Short Chain Fatty Acids in Allergy: A Prophylactic Therapy for Future
Immunol Lett. 2023 Jun 2:S0165-2478(23)00096-2. doi: 10.1016/j.imlet.2023.06.002. Online ahead of print.ABSTRACTAllergic diseases are broadly classified as IgE-mediated type-I hypersensitivity immune reactions due to exposure to typically harmless substances known as allergens. These allergenic substances activate antigen presenting cells, which further triggers T-helper 2 cells immune response and class switch B-cells for synthesis of allergen-specific IgE, followed by classical activation of inflammatory mast cells and eosinophils, which releases preformed mediators involved in the cascade of allergic symptoms. However, ...
Source: Immunology Letters - June 4, 2023 Category: Allergy & Immunology Authors: Mrudula M Mohanan Radhakrishna Shetty Claus Heiner Bang-Berthelsen Kiran Kumar Mudnakudu-Nagaraju Source Type: research

Anti-inflammatory Effects of Ziziphus Jujube Mill on LPS-induced Acute Lung Injury in Mice
Iran J Allergy Asthma Immunol. 2023 Jun 16;22(3):281-289. doi: 10.18502/ijaai.v22i3.13056.ABSTRACTZiziphus Jujuba Mill (Z.J) is a well-known ethnomedical source of biologically active compounds with anti-inflammatory effects. However, its significance in acute lung injury (ALI) has never been studied. The present study aimed to explore whether Z.J could attenuate lipopolysaccharide (LPS)-induced inflammatory responses in an experimental model of ALI. Male BALB/c mice received an intratracheal administration of LPS (n=32) or phosphate buffer saline (PBS) (control, n=8). Within 1, 11, and 23 h post-LPS injection, mice were r...
Source: Iranian Journal of Allergy, Asthma and Immunology - July 31, 2023 Category: Allergy & Immunology Authors: Parastoo Shaban Niloofar Honari Nafiseh Erfanian Mehran Hosseini Hossein Safarpour Saeed Nasseri Source Type: research