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Interpretation of Post-Pneumococcal Vaccine Antibody Levels: Concerns and Pitfalls
Publication date: Available online 27 December 2018Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Caitlin MG. McNulty, James T. Li
Source: The Journal of Allergy and Clinical Immunology: In Practice - December 28, 2018 Category: Allergy & Immunology Source Type: research

Severe Necrotic Reaction to 23-Valent Polysaccharide Pneumococcal Vaccine in a Patient With STAT3 Deficiency
Publication date: Available online 15 February 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Mervin Piñones, Cecilia Vizcaya, Guillermo Pérez-Mateluna, Rodrigo Hoyos-Bachiloglu, Arturo Borzutzky
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 16, 2019 Category: Allergy & Immunology Source Type: research

Expecting the Unexpected: Complement screening in the meningococcal vaccination era
Publication date: Available online 20 February 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Priscilla H. Wong, Rachel U. Lee
Source: The Journal of Allergy and Clinical Immunology: In Practice - February 21, 2019 Category: Allergy & Immunology Source Type: research

Interpretation of post–pneumococcal vaccine antibody levels: Concerns and pitfalls
Publication date: March 2019Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 7, Issue 3Author(s): Caitlin M.G. McNulty, James T. Li
Source: The Journal of Allergy and Clinical Immunology: In Practice - March 4, 2019 Category: Allergy & Immunology Source Type: research

Sex differences in antibody responses to the 23-valent pneumococcal polysaccharide vaccination
Ann Allergy Asthma Immunol. 2021 Jul 20:S1081-1206(21)00512-3. doi: 10.1016/j.anai.2021.07.013. Online ahead of print.NO ABSTRACTPMID:34298171 | DOI:10.1016/j.anai.2021.07.013
Source: Annals of Allergy, Asthma and Immunology - July 23, 2021 Category: Allergy & Immunology Authors: Sergio E Chiarella Sarah M Jenkins Miguel A Park Roshini S Abraham Avni Y Joshi Source Type: research

An Enzyme-Linked ImmunoSpot Assay (ELISPOT) to Assess Pneumovax ® Response when on Intravenous Immunoglobulin
CONCLUSION: Our pilot study suggests an optimized ELISPOT protocol has utility to assess the P23-specific antibody response after vaccination. Our ELISPOT assay seemed reliable for patients on IVIG and may help differentiate true CVID patients from those with a less stringent diagnosis while on IVIG.PMID:34391898 | DOI:10.1016/j.anai.2021.08.003
Source: Annals of Allergy, Asthma and Immunology - August 15, 2021 Category: Allergy & Immunology Authors: Neema Izadi Vijaya Knight Matthew Strand Harry R Hill Lisa K Peterson Pia J Hauk Source Type: research

Pediatric health care professionals ’ vaccine knowledge, awareness and attitude: a survey within the Italian Society of Pediatric Allergy and Immunology
ConclusionsOur results indicate that pHCPs ’ attitude and confidence in regards to vaccines remain suboptimal. Current COVID-19 pandemic and the rapid development of vaccines could increase vaccine hesitancy. Due to the documented pHCPs’ influence in the parental decision, educational interventions are needed to improve their level of kn owledge and counselling skills in order to address parental vaccine hesitancy and to maintain continuity of immunization services.
Source: Italian Journal of Pediatrics - September 9, 2021 Category: Pediatrics Source Type: research

Specific antibody deficiency: Pearls and pitfalls for diagnosis
CONCLUSION: Clinical evaluations in individuals with self-reported recurrent acute sinusitis or lower respiratory infections need to document an infectious etiology with pyogenic bacteria and must rule out an underlying primary airway inflammatory disorder before consideration is made regarding the presence of an immune deficiency. In addition, decision making regarding diagnosis and treatment of patients being evaluated for humoral immunodeficiency should not hinge solely on the strict application of defined cutoffs for "normal" response to a single polysaccharide vaccine, but rather a global assessment of humoral immune ...
Source: Annals of Allergy, Asthma and Immunology - June 7, 2022 Category: Allergy & Immunology Authors: Monica G Lawrence Larry Borish Source Type: research

A Critical View of Specific Antibody Deficiencies
Ricardo U. Sorensen1,2,3* 1Professor Emeritus of Pediatrics, Department of Pediatrics, Louisiana State University Health Science Center, New Orleans, LA, United States 2Louisiana Primary Immunodeficiency Network, New Orleans, LA, United States 3Honorary Professor, Faculty of Medicine, University of La Frontera, Temuco, Chile In thisopinion manuscript the author postulates that the present definition of Specific Antibody Deficiency (SAD) needs to be revised and expanded. It is presently defined as a syndrome of low IgG antibody responses to purified Streptococcus pneumoniae capsular polysaccharides vaccine...
Source: Frontiers in Immunology - April 30, 2019 Category: Allergy & Immunology Source Type: research

Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta Syndrome
This study was carried out after written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. The protocol was approved by the Stanford University and UCLA Institutional Review Boards. Author Contributions MB provided patient care and obtained IRB approval. RO prepared histology images. MB, TT, and RB designed the research. TT and LP conducted experiments and analyzed data. MB made the molecular model. MB and TT wrote the manuscript. Funding Funding for this work came from the Jeffrey Modell Foundation and from the NIH/NIGMS (R01 GM110482 to MB)....
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research

Keeping Athletes Healthy at the 2020 Tokyo Summer Games: Considerations and Illness Prevention Strategies
Conclusion It is apparent that athletes will be exposed to various stressors during both the preparatory and competition phases of the Summer Games. Athletes residing in the southern hemisphere appear to be at increased risk for illness during the preparatory phase, while female, Paralympic, water-sport and multi-competition/event athletes may be more susceptible to illness during the competition phase of the Summer Games. To maintain athlete health, illness prevention strategies should be targeted to stressors and at-risk athletes. Keeping athletes healthy will contribute to optimal Olympic and Paralympic athletic perfor...
Source: Frontiers in Physiology - April 16, 2019 Category: Physiology Source Type: research

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