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Procedure: Gastroschisis Repair

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Total 540 results found since Jan 2013.

Contemporary applications of frontal sinus trephination: A systematic review of the literature
Our objective was to perform a systematic review of the literature on contemporary indications and outcomes for frontal sinus trephination and present an illustrative case of an endoscopically assisted repair of a subcutaneous frontal sinus fistula by trephination technique. PubMed and Ovid databases were used as data sources. A systematic review of the English literature was completed to review reports of frontal trephination from 1980 to 2014. Articles meeting inclusion criteria for inflammatory and noninflammatory indications were reviewed. Articles were systematically reviewed and graded by evidence‐based medicine le...
Source: The Laryngoscope - February 1, 2015 Category: ENT & OMF Authors: Alpen B. Patel, Rachel B. Cain, Devyani Lal Tags: Allergy/Rhinology Source Type: research

Employment of Synthetic Patch With Augmentation of the Long Head of the Biceps Tendon in Irreparable Lesions of the Rotator Cuff: Our Technique Applied to 60 Patients
Conclusions: The results of our study suggest that employing this surgical technique in patients (appropriately selected) with an irreparable rotator cuff tear can lead to pain relief and improved clinical outcome.
Source: Techniques in Hand and Upper Extremity Surgery - February 26, 2015 Category: Surgery Tags: Techniques Source Type: research

Holding the inflammatory system in check: NLRs keep it cool.
This report aims to review the literature regarding several members of the nucleotide-binding domain, leucine-rich repeat-containing receptor (NLR) family of pattern recognition sensors/receptors that serve as checkpoints for inflammation. Understanding the negative regulation of inflammation is highly relevant to the development of therapeutics for inflammatory as well as infectious diseases. PMID: 25750733 [PubMed]
Source: F1000 Medicine Reports - March 12, 2015 Category: Biomedical Science Tags: F1000Prime Rep Source Type: research

Failure pressures of three rhinologic dural repairs in a porcine ex vivo model
ConclusionThe BP repair showed significantly higher tolerances for pressure than the other 2 repairs. The BP repair was the only technique that withstood adult physiologic supine cerebrospinal fluid (CSF) pressure.
Source: International Forum of Allergy and Rhinology - March 1, 2015 Category: Allergy & Immunology Authors: Ryan P. Lin, Erik Kent Weitzel, Philip G. Chen, Kevin Christopher McMains, Jacob Majors, Leonid Bunegin Tags: ORIGINAL ARTICLE Source Type: research

IL‐33 drives airway hyper‐responsiveness through IL‐13‐mediated mast cell: airway smooth muscle crosstalk
ConclusionIL‐33 directly promotes mast cell activation and ASM wound repair but indirectly promotes ASM contraction via upregulation of mast cell‐derived IL‐13. This suggests that IL‐33 may present an important target to modulate mast cell–ASM crosstalk in asthma.
Source: Allergy - March 16, 2015 Category: Allergy & Immunology Authors: D. Kaur, E. Gomez, C. Doe, R. Berair, L. Woodman, R. Saunders, F. Hollins, F.R. Rose, Y. Amrani, R. May, J. Kearley, A. Humbles, E.S. Cohen, C.E. Brightling Tags: Original Article Source Type: research

IL-17 and neutrophils: unexpected players in the type 2 immune response.
Abstract The study of immunity to helminth infection has been central to understanding the function of type 2 cytokines and their targets. Although type 2 cytokines are considered anti-inflammatory and promote tissue repair, they also contribute to allergy and fibrosis. Here, we utilise data from helminth infection models, to illustrate that IL-17 and neutrophils, typically associated with pro-inflammatory responses, are intimately linked with type 2 immunity. Neutrophils work with IL-4Rα-activated macrophages to control incoming larvae but this comes at a cost of enhanced tissue damage. Chitinase like proteins (...
Source: Current Opinion in Immunology - March 17, 2015 Category: Allergy & Immunology Authors: Allen JE, Sutherland TE, Rückerl D Tags: Curr Opin Immunol Source Type: research

Chemokine receptors and their therapeutic opportunities in diseased lung: Far beyond leukocyte trafficking
Chemokine receptors and their chemokine ligands, key mediators of inflammatory and immune cell trafficking, are involved in the regulation of both physiological and pathological processes in the lung. The discovery that chemokine receptors/chemokines, typically expressed by inflammatory and immune cells, are also expressed in structural lung tissue cells suggests their role in mediating the restoration of lung tissue structure and functions. Thus, chemokine receptors/chemokines contribute not only to inflammatory and immune responses in the lung but also play a critical role in the regulation of lung tissue repair, regener...
Source: AJP: Lung Cellular and Molecular Physiology - April 1, 2015 Category: Respiratory Medicine Authors: Tomankova, T., Kriegova, E., Liu, M. Tags: REVIEWS Source Type: research

mutations associated with immunodeficiency, granuloma, and autoimmune regulator–dependent autoimmunity
PRKDC encodes for DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a kinase that forms part of a complex (DNA-dependent protein kinase [DNA-PK]) crucial for DNA double-strand break repair and V(D)J recombination. In mice DNA-PK also interacts with the transcription factor autoimmune regulator (AIRE) to promote central T-cell tolerance.
Source: Journal of Allergy and Clinical Immunology - April 1, 2015 Category: Allergy & Immunology Authors: Anne-Laure Mathieu, Estelle Verronese, Gillian I. Rice, Fanny Fouyssac, Yves Bertrand, Capucine Picard, Marie Chansel, Jolan E. Walter, Luigi D. Notarangelo, Manish J. Butte, Kari Christine Nadeau, Krisztian Csomos, David J. Chen, Karin Chen, Ana Delgado, Source Type: research

Angiogenic T cells are decreased in rheumatoid arthritis patients
Conclusions Disease-specific parameters, including disease activity, autoantibody profiles and IFNα levels, are associated with Tang decrease in RA, thus probably accounting for CVR.
Source: Annals of the Rheumatic Diseases - April 2, 2015 Category: Rheumatology Authors: Rodriguez-Carrio, J., Alperi-Lopez, M., Lopez, P., Alonso-Castro, S., Ballina-Garcia, F. J., Suarez, A. Tags: Immunology (including allergy), Obesity (nutrition), Connective tissue disease, Degenerative joint disease, Musculoskeletal syndromes, Rheumatoid arthritis Basic and translational research Source Type: research

Functional analysis of naturally occurring mutations and correlation with the clinical phenotype of ARTEMIS deficiency
The endonuclease ARTEMIS, which is encoded by the DCLRE1C gene, is a component of the nonhomologous end-joining pathway and participates in hairpin opening during the V(D)J recombination process and repair of a subset of DNA double-strand breaks. Patients with ARTEMIS deficiency usually present with severe combined immunodeficiency (SCID) and cellular radiosensitivity, but hypomorphic mutations can cause milder phenotypes (leaky SCID).
Source: Journal of Allergy and Clinical Immunology - April 25, 2015 Category: Allergy & Immunology Authors: Kerstin Felgentreff, Yu Nee Lee, Francesco Frugoni, Likun Du, Mirjam van der Burg, Silvia Giliani, Ilhan Tezcan, Ismail Reisli, Ester Mejstrikova, Jean-Pierre de Villartay, Barry P. Sleckman, John Manis, Luigi D. Notarangelo Source Type: research

ORMDL deregulation increases stress responses and modulates repair pathways in airways
Genome-wide association studies found that childhood asthma is highly associated with polymorphisms in a locus on chromosome 17q21, especially with the gene orosomucoid 1-like 3 (ORMDL3).1 Carriers of the asthma risk allele have increased ORMDL3 expression.2ORMDL3 is 1 of 3 members of the ORMDL family in mammals; it encodes an endoplasmic reticulum transmembrane protein that is implicated in diverse cellular processes. Elucidation of ORMDL3's functional relevance in asthma pathogenesis has been hindered by extensive similarities between all 3 ORMDL proteins (ORMDL1-3) as well as their strongly overlapping expression patterns.
Source: Journal of Allergy and Clinical Immunology - May 12, 2015 Category: Allergy & Immunology Authors: Kimberley Kallsen, Nicole Zehethofer, Ahmed Abdelsadik, Buko Lindner, Michael Kabesch, Holger Heine, Thomas Roeder Tags: Letter to the Editor Source Type: research

Radiation-sensitive severe combined immunodeficiency: The arguments for and against conditioning before hematopoietic cell transplantation—what to do?
Defects in DNA cross-link repair 1C (DCLRE1C), protein kinase DNA activated catalytic polypeptide (PRKDC), ligase 4 (LIG4), NHEJ1, and NBS1 involving the nonhomologous end-joining (NHEJ) DNA repair pathway result in radiation-sensitive severe combined immunodeficiency (SCID). Results of hematopoietic cell transplantation for radiation-sensitive SCID suggest that minimizing exposure to alkylating agents and ionizing radiation is important for optimizing survival and minimizing late effects. However, use of preconditioning with alkylating agents is associated with a greater likelihood of full T- and B-cell reconstitution com...
Source: Journal of Allergy and Clinical Immunology - June 5, 2015 Category: Allergy & Immunology Authors: Morton J. Cowan, Andrew R. Gennery Tags: Rostrum Source Type: research

Follistatin-like protein 1 regulates chondrocyte proliferation and chondrogenic differentiation of mesenchymal stem cells
Conclusions FSTL1 is a potent regulator of chondrocyte proliferation, differentiation and expression of ECM molecules. Our findings may lead to the development of novel strategies for cartilage repair and provide new disease-modifying treatments for OA.
Source: Annals of the Rheumatic Diseases - June 10, 2015 Category: Rheumatology Authors: Chaly, Y., Blair, H. C., Smith, S. M., Bushnell, D. S., Marinov, A. D., Campfield, B. T., Hirsch, R. Tags: Genetics, Immunology (including allergy), Degenerative joint disease, Musculoskeletal syndromes, Osteoarthritis Basic and translational research Source Type: research

Stimulatory effects of histamine on migration of nasal fibroblasts
ConclusionWe showed that histamine stimulates fibroblast migration in nasal fibroblasts. This effect appeared to be mediated by HR1 and HR4. However, because fibroblast migration also can be involved in scaring and fibrosis, more research is necessary to determine the effects of antihistamine on wound healing after sinus surgery.
Source: International Forum of Allergy and Rhinology - June 10, 2015 Category: Allergy & Immunology Authors: Sung‐Moon Hong, Il‐Ho Park, Ji‐Young Um, Jae‐Min Shin, Heung‐Man Lee Tags: ORIGINAL ARTICLE Source Type: research

8 Foods That Are Good For Your Skin
SPECIAL FROM Grandparents.com There's an endless supply of new skin care products hitting drugstores and specialty stores every day, but that doesn't mean you necessarily need them. Shopping for skin care can be both expensive and time consuming. And there's nothing more frustrating than bringing home a pricey cream only to discover that it doesn't even work. The next time you have a dry patch or irritation, forget going to the store. Instead, head straight for your own fridge or pantry. Odds are you already own some fantastic skin care ingredients—you may have even had them for breakfast. Citrus Fruits Vitamin C is a...
Source: Healthy Living - The Huffington Post - June 21, 2015 Category: Consumer Health News Source Type: news